Find Academic Supervisors

Richard GoodmanView profile

Professor

• Gene Expression Regulation
• Transcription Factors
• Molecular Biology
• +3 more

Richard Goodman is a Professor of Cell, Developmental and Cancer Biology and Biochemistry and Molecular Biology at Oregon Health & Science University, serving as a senior scientist at the Vollum Institute where he directed from 1990 to 2016. His research bridges molecular biology and neuroscience with focus on metabolic regulation of gene expression. His educational background includes: B.S. in Chemistry, Massachusetts Institute of Technology (1970) M.D., University of Pennsylvania (1976) Ph.D., University of Pennsylvania (1976) Dr. Goodman pioneered the characterization of the cAMP regulated enhancer (CRE) and identification of the CREB coactivator CBP. His lab conducts genome-wide analyses of transcription factor binding and investigates microRNA roles in neuronal plasticity, circadian rhythms, and metabolic regulation. Current work emphasizes activity-regulated genes and metabolic pathways in neuronal function. Analysis of his publication record reveals consistent innovation in molecular tools and conceptual advances. His lab developed fluorescent biosensors for metabolites like NAD+ and fructose-1,6-bisphosphate, enabling real-time metabolic imaging in neurons. Research spans from transcriptional mechanisms to in vivo synaptic plasticity, with microRNA regulation emerging as a unifying theme across neuronal development, circadian adaptation, and neurodegeneration. His scientific recognition includes: National Academy of Sciences, elected member (2002) Institute of Medicine, elected member (2005) Scientific Review Board, Howard Hughes Medical Institute (2008-2011) Dr. Goodman has mentored 14 graduate students and 29 fellows, many becoming independent investigators. His research is supported by sustained NIH funding for studies on transcriptional regulation, metabolic neuroscience, and microRNA mechanisms. Current grants focus on neuronal metabolism and activity-dependent gene expression. As a senior scientist at the Vollum Institute, he leads a multidisciplinary team developing cutting-edge metabolic imaging tools. His lab collaborates extensively across neuroscience and molecular biology departments, with ongoing projects examining glycolytic dynamics in neural circuits and microRNA-mediated regulation of synaptic function.

Benjamin SivyerView profile

Professor

• Visual Neuroscience
• neural circuits
• Electrophysiology
• +5 more

Dr. Benjamin Sivyer is a leading researcher in visual neuroscience specializing in retinal circuitry and neuronal dysfunction, particularly in the context of glaucoma. He directs the Sivyer Lab and serves as principal investigator on multiple NIH-funded research projects focused on understanding how eye diseases disrupt normal retinal processing. His research interests center on visual neuroscience, neural circuits, electrophysiology, and glaucoma. Dr. Sivyer employs an integrative approach combining multielectrode array systems, patch-clamp recordings, high-resolution confocal microscopy, behavioral studies, and transcriptomic analyses to investigate visual processing mechanisms in both healthy and diseased retinas. His work particularly focuses on how axon injury and diseases like glaucoma disturb normal retinal function. Dr. Sivyer's publication record demonstrates consistent contributions to understanding retinal ganglion cells, direction selectivity mechanisms, and glaucoma-related neurodegeneration. His recent work (2023-2025) shows increasing focus on molecular and spatial analysis techniques, neuroprotection in glaucoma, and advanced imaging methods for studying retinal structure and function. His research bridges fundamental neuroscience with clinical applications in ophthalmology. His scientific achievements include the NHMRC CJ Martin Biomedical Research Fellowship awarded in 2015. His current research is supported by multiple NIH grants including: NIH NEI 1R01EY034973 (2023-28) NIH NEI 1R01EY032564 (2022-27) NIH NEI 2R01 EY027202 (2022-26) NIH NEI U24EY033269 (2021-26) NIH NEI R01 EY030429 (2020-25) Dr. Sivyer's lab employs advanced techniques for visualizing and recording from retinal neurons to understand disease mechanisms. His research group investigates how retinal circuits process visual information and how these circuits are perturbed by disease, with particular emphasis on glaucoma as a model of retinal ganglion cell degeneration.

Laurence TrussellView profile

Professor

• Auditory Neuroscience
• Synaptic Physiology
• Neural Circuits
• +1 more

Laurence Trussell is a Professor and Interim Director of the Oregon Hearing Research Center at Oregon Health & Science University (OHSU), with concurrent appointment as a Scientist at the Vollum Institute. His research focuses on neural mechanisms of hearing, particularly brainstem circuitry and synaptic physiology in auditory processing. Education: Ph.D. in Biology, University of California, Los Angeles (1983) Research Interests: Dr. Trussell investigates how brainstem circuits encode acoustic signals and how synaptic physiology preserves auditory information. His seminal work demonstrates that timing-encoding neurons are molecularly specialized, reveals synaptic learning mechanisms at early sensory stages, and elucidates co-release of transmitters acting on single receptors. His research integrates molecular, biophysical, and circuit-level approaches to dissect auditory processing. Publication Trends: His 2013-2025 publications consistently explore dorsal cochlear nucleus physiology, emphasizing synaptic transmission mechanisms ( e.g. , glutamate dynamics, KCNQ channels), neural oscillations, electrical coupling, and cell-type-specific circuitry. Key themes include calcium channel nanodomains, inhibitory neuron subtypes, and multimodal integration, reflecting his focus on fundamental mechanisms of auditory signal processing from cellular to circuit levels. Advising and Grants: Publicly available information does not specify doctoral advisees or grant funding details, though his leadership of major research centers implies significant mentorship and extramural support. Labs and Teams: He directs research at the Oregon Hearing Research Center and Vollum Institute, leading teams studying auditory pathways through electrophysiology, imaging, and molecular techniques to decode hearing mechanisms and disorders.

Byung ParkView profile

Professor

• Biostatistics
• Oncology Clinical Trials
• Immunology
• +2 more

Byung Park serves as Professor of Biostatistics at the OHSU-PSU School of Public Health, Director of the Biostatistics Shared Resource (BSR) at Knight Cancer Institute, and Associate Director of the Biostatistics and Bioinformatics Core (BBC) at Oregon National Primate Research Center. With continuous service since 2002, he provides critical statistical leadership for oncology and primate research initiatives across Oregon Health & Science University. His educational foundation includes: B.A. (1990) from Sung Kyun Kwan University M.S. (1992) from Sung Kyun Kwan University Ph.D. (2002) from Oregon State University Dr. Park specializes in oncology clinical trial design and immunology analysis, maintaining 20+ years of collaboration with Knight Cancer Institute and Oregon National Primate Research Center. His research integrates biostatistical methods with translational studies in cancer biomarkers, aging neuroscience, and perinatal health, particularly investigating maternal smoking effects and vitamin C interventions. This work frequently employs advanced longitudinal modeling and multi-omics integration. His publication record reveals consistent contributions to high-impact journals, with recent emphasis on pancreatic cancer biomarkers, primate aging models, and perinatal epigenetic mechanisms. Collaborative projects span statistical methodology development for complex clinical endpoints and biomarker validation in diverse disease contexts. His scientific recognition includes: Jerome Lee Award from Oregon State University (2002) AACR Cancer Biostatistics Workshop Scholarship (2008) As active reviewer for Knight Cancer Institute's Clinical Research Review Committee and Data Safety Monitoring Committee, Dr. Park ensures methodological rigor in clinical trials. He mentors junior biostatisticians through his leadership roles while developing statistical frameworks for grant-funded research across OHSU. The Biostatistics Shared Resource under his direction supports over 100 cancer research projects annually, while the BBC at ONPRC provides bioinformatics infrastructure for primate studies, creating synergies between statistical innovation and biological discovery.

Tomohisa TodaView profile

Professor

• Neuroscience
• Epigenetics
• Aging Research
• +7 more

Professor Tomohisa Toda leads a research group at the Max Planck Center for Physics and Medicine in Erlangen, Germany, where he investigates the mechanisms that allow the brain to maintain neuronal function throughout life. His work focuses on understanding how neurons preserve their cellular identity and functionality over decades without significant cell renewal, with particular emphasis on epigenetic regulation and nuclear architecture. Dr. Toda's research program examines how epigenetic mechanisms regulate gene activity in neurons without altering DNA sequences, investigating these processes at multiple scales - from DNA modifications to nuclear stiffness and geometry. His team has made significant discoveries including the identification of long-lived RNAs (LL-RNAs) in the brain that challenge traditional views of RNA stability, and the role of nuclear structural proteins like Lamin B1 and nuclear pore proteins in adult hippocampal neurogenesis. The research trends across his publications reveal a consistent focus on the intersection of nuclear architecture, epigenetic regulation, and brain aging. His work spans molecular neuroscience, cell biology, and aging research, with particular emphasis on how physical properties of the cell nucleus serve as epigenetic information. Recent publications increasingly connect these fundamental mechanisms to age-related neurological disorders, particularly Alzheimer's disease. Dr. Toda actively engages with students and visitors at his institution, as evidenced by his recent hosting of students from Nuremberg for insights into research at the physics-medicine interface. His laboratory continues to advance understanding of neuronal longevity mechanisms that could inform future treatments for neurodegenerative conditions.

• Neurodegenerative Diseases
• Molecular Neuroscience
• Stroke Research
• +4 more

Kert Mätlik is a neuroscientist specializing in molecular mechanisms of neurodegenerative diseases and stroke pathology. Affiliated with Tallinn University of Technology, he holds a Doctor's Degree from the University of Helsinki (2017) and a Master's Degree from Tallinn University of Technology (2005). His research focuses on neurotrophic factors, particularly MANF and CDNF proteins, and their therapeutic potential in neurological disorders. Education: Doctor's Degree (2017), University of Helsinki, Institute of Biotechnology Master's Degree (2005), Tallinn University of Technology Dr. Mätlik's research program investigates cell-type-specific responses in neurodegenerative conditions, with significant contributions to understanding Huntington's disease mechanisms and stroke recovery processes. His work employs advanced molecular techniques to profile specific neuronal populations in human brain tissue, revealing critical insights into selective neuronal vulnerability. Recent publications demonstrate his leadership in developing methodologies for isolating and analyzing nuclei from specific neuronal types in human cerebral cortex and striatum. Analysis of his publication trends shows a consistent focus on translational neuroscience, bridging molecular mechanisms with potential therapeutic applications. His work spans neurodegenerative diseases, stroke pathology, and pain mechanisms, with increasing emphasis on human tissue studies in recent years. Scientific Recognition: 2002 First Prize in National Student Research Competition Artur Linnu Scholarship in Gene Technology Dr. Mätlik maintains active research collaborations across international institutions, contributing to our understanding of neurotrophic factor signaling and developing novel approaches for treating neurological disorders. His current work continues to advance the field of cell-type-specific analysis in neurodegenerative disease research.

Maren SchrölkampView profile

Researcher

• Molecular Cardiology
• Membrane Proteins
• Cardiovascular Genetics
• +4 more

Maren Schrölkamp is an Academic employee with an MSc in Biochemistry at the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen. She is affiliated with the Molecular Cardiology and Membrane Proteins research group and maintains an active research profile with publications in high-impact journals such as Nature Communications, European Heart Journal, and Frontiers in Cell and Developmental Biology. Her ORCID profile (0000-0003-3522-6379) documents her scholarly contributions to biomedical research. Her research interests span multiple interconnected domains in biomedical sciences, with primary focus on Molecular Cardiology and Membrane Proteins . Her work explores cardiovascular genetics, proteomics of cardiac tissues, adipose stem cell biology in obesity, and epigenetic mechanisms in metabolic disorders. She has contributed to understanding the molecular basis of conditions including mitral valve prolapse, diabetes in pregnancy, and narcolepsy. Her research methodology frequently employs advanced techniques such as quantitative proteomics, transcriptomics, and genome-wide association studies. Analysis of her seven recent publications reveals a strong emphasis on molecular mechanisms underlying cardiovascular diseases, with growing interest in genetic and epigenetic factors. Her work shows increasing collaboration with international research teams, particularly evident in her 2022 European Heart Journal publication with 34 additional authors. The research spans basic science investigations of cellular mechanisms to clinical applications in cardiovascular genetics and metabolic disorders. Maren Schrölkamp has no publicly listed scientific awards in the provided information. Her research has been disseminated through multiple peer-reviewed publications with significant citation impact, including 84 citations for her Nature Communications paper on cardiac pacemaking mechanisms. While specific grant information is not provided in the text, her collaborative publications suggest participation in multi-institutional research projects. The diversity of her research topics indicates involvement in multiple research initiatives across cardiovascular biology, metabolic disorders, and sleep medicine. She is actively affiliated with the Molecular Cardiology and Membrane Proteins research group at the University of Copenhagen's Department of Biomedical Sciences. This research environment focuses on understanding the molecular mechanisms of cardiovascular function and disease, utilizing advanced proteomic and genomic techniques to investigate cardiac biology at the cellular and molecular levels.

• Metabolic Disorders
• Neuroendocrinology
• Immunology
• +3 more

Hannah Louise Zakariassen is a Postdoctoral Researcher at the University of Copenhagen's Faculty of Health and Medical Sciences, with dual affiliations in the Department of Biomedical Sciences (Nutritional Immunology group) and the Department of Veterinary and Animal Sciences (Graduate Programme for In Vivo Pharmacology and Experimental Animals). She is based at the Blegdamsvej 3 campus in Copenhagen. Her research focuses on the intersection of metabolism, neuroendocrinology, and immunology, with particular expertise in gut hormones, energy balance regulation, and mucosal immunology. Dr. Zakariassen's work bridges basic science with clinical applications, particularly in obesity and metabolic disorders. Analysis of her publication record reveals a strong focus on neurotensin signaling in weight maintenance, amylin/calcitonin receptor agonists for metabolic disease treatment, and the relationship between gut integrity and immune function. Her research employs both clinical trial data and sophisticated rodent models to investigate mechanisms of metabolic regulation. Her scientific contributions have attracted significant attention, with multiple publications receiving news coverage and substantial readership on academic platforms like Mendeley. Dr. Zakariassen collaborates extensively with leading researchers at the University of Copenhagen, including Hannelouise Kissow and Jens Juul Holst, indicating integration within prominent metabolic research groups at the institution.

Graham LieschkeView profile

Professor

• Haematology
• Blood cell development
• Leukocytes (neutrophils and macrophages)
• +10 more

Professor Graham Lieschke is a distinguished clinical and research haematologist at Monash University with a dual appointment as a clinical haematologist at the Royal Melbourne Hospital. Internationally recognized for his innovative research using zebrafish and mice models, he specializes in blood disorders and cancer, particularly focusing on leukocyte biology in inflammation and infection. His educational background includes: Medical science and medical degrees from the University of Melbourne (1983) Specialist clinical training in medical oncology at the Royal Melbourne Hospital (FRACP 1991) PhD at the Ludwig Institute for Cancer Research (Melbourne Branch) Postdoctoral training at the Whitehead Institute in Cambridge, Massachusetts, USA Professor Lieschke's research program centers on blood cell development and function, with particular emphasis on leukocytes (neutrophils and macrophages). His work exploits the unique strengths of the zebrafish model in genetics, embryology, and in vivo cell behavior visualization. Key research areas include developmental haematology, genetic causes of neutropenia, leukocyte dysfunction, and leukocyte functional biology in inflammation and infection. His clinical work involves multiple phase 1-3 clinical studies in the treatment and supportive care of leukaemia and lymphoma patients. Analysis of Professor Lieschke's recent publications reveals a strong focus on neutrophil and macrophage biology using zebrafish models. His research spans immunology, microbiology, and hematology, with particular emphasis on host-pathogen interactions, inflammatory responses, and genetic mechanisms of blood cell development. The work demonstrates an interdisciplinary approach combining genetics, cell biology, and clinical applications. Professor Lieschke has received numerous prestigious awards: John Maynard Hedstrom Research Fellowship of the Cancer Council of Victoria Howard Hughes Postdoctoral Research Fellowship for Physicians Wellcome Trust Senior Research Fellowship NHMRC Senior Research Fellowship Ludwig Institute's inaugural George Hodgson Medal for Medical Science 2004 Dame Roma Mitchell Churchill Fellowship As a laboratory head and principal investigator, Professor Lieschke has secured significant research funding through fellowships including NHMRC and Wellcome Trust awards. His research group has made substantial contributions to understanding granulopoiesis and leukocyte function. He has also been actively involved in clinical trials related to haematological malignancies and has co-edited influential books including "Zebrafish: Methods and Protocols" (2009). Professor Lieschke leads a research team focused on zebrafish models of blood disorders and has been instrumental in developing this model system for haematological research. He served as President of the International Zebrafish Society (2018-2019) and is actively involved in multiple professional societies including the Haematology Society of Australia and New Zealand and the American Society of Hematology.