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Xi RenView profile

Assistant Professor

• Tissue Engineering
• Regenerative Medicine
• Biomanufacturing
• +7 more

Xi (Charlie) Ren is an Assistant Professor in the Department of Biomedical Engineering at Carnegie Mellon University's College of Engineering. He leads the Ren Lab, focusing on tissue engineering, vascular regeneration, and biomanufacturing. He is affiliated with the Bioengineered Organs Initiative and the Manufacturing Futures Institute. Education: Ph.D. in Cell Biology, Peking University (2011) BS in Biological Science, Peking University (2005) His research centers on engineering functional tissues using decellularized scaffolds, DNA nanotechnology, and organoid systems. Key areas include vascular engineering, lung regeneration, bioorthogonal functionalization, and synthetic cell protection. His lab develops innovative platforms such as apical-out airway organoids and DNA-based cell armor. The recent publications (2025–2023) highlight a strong trend in leveraging DNA nanotechnology for intracellular delivery and cell ruggedization, chemoselective biomaterial modification, and advanced organoid and vascular engineering. Keywords across these works include tissue engineering, regenerative medicine, nanotechnology, and extracellular matrix dynamics. Scientific Awards: NSF CAREER Award NIH Bioengineering Partnerships with Industry (BPI) Grant American Heart Association Collaborative Sciences Award BMES-CMBE Rising Star Award Charles E. Kaufman Foundation Grant Dean’s Early Career Fellow at CMU Ren actively mentors graduate students, including NIH-funded Ph.D. student Dhruv Bhattaram. He has secured major grants from NIH, NSF, ARPA-H, and the Kaufman Foundation, often in collaboration with institutions like the University of Pittsburgh and NASA. His work has significant translational potential in regenerative medicine and organ transplantation. He leads research in the Ren Lab, contributing to the Bioengineered Organs Initiative and advancing 3D micro-ice printing and DNA nanotechnology applications in medicine.

Linda DagiView profile

Associate Professor

• Pediatric Ophthalmology
• Neuro-Ophthalmology
• Strabismus Surgery
• +3 more

Linda Dagi, MD, is an Associate Professor at Harvard Medical School and a key figure in the Department of Ophthalmology at Boston Children's Hospital. She serves as Director of multiple strabismus services and leads quality assurance initiatives in ophthalmology. Education: Harvard College (1978) Harvard Medical School (1983) Georgetown University Hospital internship/residency Boston Children's Hospital fellowship Research Focus: Pediatric and adult strabismus, craniofacial disorders like Apert and Crouzon syndromes, optic neuropathy in craniosynostosis, and surgical outcomes. Her work employs high-resolution orbital imaging and 3D modeling to refine surgical approaches. Publication Trends: Recent studies address nonacute esotropia , craniosynostosis-related optic atrophy , and 3rd-nerve palsy surgical techniques . Earlier works emphasize amblyopia treatment, thyroid eye disease, and pediatric pseudotumor cerebri. Labs & Teams: Collaborates with Boston Children's Hospital ophthalmology units, focusing on complex strabismus and craniofacial disorders. Supervises goal-determined outcome metrics for surgical quality improvement.

• Antimicrobial Peptides
• Urinary Tract Infections
• Innate Immunity
• +3 more

Judith Hall is a researcher at Newcastle University, focusing on antimicrobial peptides, innate immunity, and bacterial pathogenesis in the context of urinary tract infections (UTIs). She has collaborated extensively with experts like Dr. Catherine Mowbray, Professor Christopher Harding, and Dr. Phillip Aldridge, contributing to studies on Escherichia coli immune evasion, estrogen's role in mucosal defense, and the genetic regulation of antimicrobial responses. Key Research Areas: Antimicrobial peptides, host-pathogen interactions, UTI pathogenesis, hormonal immune modulation Methodologies: Molecular biology, clinical microbiology, immunological assays, bacterial population dynamics Her recent work (2022-2023) explores nitrofurantoin resistance evolution and toll-like receptor evasion mechanisms, while earlier studies (2016-2019) investigated the protective roles of hyaluronic acid, defensins, and L-form bacterial switching in recurrent UTIs. She has also contributed to methodological advancements in reconciling academic research assessments (2020). Publications from 2004-2016 highlight her work on defensin expression in human tissues, prostate-specific antigen's antimicrobial functions, and the molecular biology of avian proteins like AWAK and LEAP-2. Despite no explicit mention of awards or mentoring students in the provided data, her extensive co-authorship history underscores her role in collaborative biomedical research.

Vickery Trinkaus-RandallView profile

Professor

• Purinoreceptors
• EGFR receptors
• Confocal imaging
• +6 more

Vickery Trinkaus-Randall is a Professor in the Department of Biochemistry at Boston University. Her research focuses on cellular responses to injury, particularly in corneal wound healing and diabetic complications. University: Boston University Department: Biochemistry Email: vickery@bu.edu Her lab investigates corneal injury responses using pre-Type II diabetic models, emphasizing purinergic signaling , EGFR receptor dynamics , and pannexin protein roles . Key methods include confocal imaging , live calcium mobilization tracking , and MATLAB-based analysis of cytoskeletal changes. Recent publications reveal research trends in corneal biomechanics (substrate stiffness effects), hypoxia-induced matrix remodeling , and diabetic corneal innervation changes . Collaborative studies span respiratory allergy mechanisms and endothelial cell mechanotransduction . Scientific Awards: Educator of the Year 2025 Her work integrates in vitro , organ culture , and in vivo models to study soluble factor signaling and cell polarity regulation during wound repair. The lab employs advanced imaging technologies and quantitative analysis to explore these processes.

Eleanor CoffeyView profile

Researcher

• Neuroscience
• Proteomics
• Neurodegenerative Diseases
• +6 more

Eleanor Coffey is a Principal Researcher at the Faculty of Natural Sciences and Technology, Åbo Akademi University, and Vice Director of the University of Turku (2015–2024). She leads the Turku Life Sciences Centre's InFLAMES flagship, focusing on immune system research ecosystems. Her work spans neuroscience, proteomics, and neurodegenerative diseases with emphasis on Parkinson's disease biomarkers, neuroinflammation, and cell signaling mechanisms. Key contributions include identifying tau protein interactions, cerebrospinal fluid diagnostics, and JNK1 pathway roles in anxiety. Academy of Finland-funded project (2024–2028) to develop proteomic Parkinson's blood tests Michael J. Fox Foundation grants (2022–2027) for lysosomal monitoring and target advancement tools 2023–2027 EuroBioimaging infrastructure leadership Scientific honors include the Elias Tillandz Prize (2011) and Nordic Life Sciences Days recognition (2019). Her media visibility highlights Parkinson's blood-brain connection discoveries and novel depression treatment mechanisms.

• Applied Mathematics
• Computational Biology
• Mathematical Biology
• +6 more

Prof Anotida Madzvamuse is a Visiting Researcher at the School of Mathematical and Physical Sciences, University of Sussex. His research lies at the intersection of applied mathematics, computational biology, and biomedical engineering, focusing on mathematical and computational approaches to experimental sciences including cell motility, pattern formation, and pandemic modeling. He has led impactful collaborations with NHS trusts, local authorities, and industrial partners like IBIDI and CYTOO, and developed the HALOGEN Covid-19 Dashboard. Education: DPhil and MSc from University of Oxford, BSc from University of Zimbabwe His research interests span applied mathematics , computational biology , and cell motility , with specific focus on reaction-diffusion systems , cell migration modeling , and epidemic forecasting . Recent work includes pandemic analytics and multiscale modeling of biological processes. His publications demonstrate expertise in virtual element methods, pattern formation, and biomedical applications. Scientific awards include the Royal Society Wolfson Research Merit Award (2016-2021) and Theodore von Kaman Fellowship (2013). He has supervised numerous PhD/MSc students and secured grants from EPSRC, Royal Society, and EU Horizon2020.

Amanda CouttsView profile

Senior Lecturer

• Cancer Biology
• Molecular Biology
• Cell Signaling and Stress Response
• +3 more

Amanda Coutts is a Senior Lecturer in the School of Science & Technology at Nottingham Trent University. Her expertise spans molecular biosciences, with a focus on tumor cell survival, motility, and the integration of transcriptional regulation with stress response mechanisms. Role: Module Leader for Cell Culture and Antibody Technology (MSc flexi), Molecular Biology and Protein Structure (UG), and Cancer/Cell Signaling modules. Research: Investigates how transcriptional co-factors like JMY link cytoskeletal events to nuclear processes during stress, impacting p53 activity and cell survival. Scientific Contributions: She has authored key publications on actin nucleation, autophagy, and DNA damage response. Her work on JMY's role in hypoxia-driven cell motility and autophagosome formation has advanced understanding of cancer metastasis and cell survival pathways. External Engagement: Dr. Coutts serves as Associate Editor for Bioscience Reports and has held editorial roles for Methods in Molecular Biology and Cell Cycle Oscillators . She is Chair of the Oxford Branch of the British Science Association (2009-2016). Memberships: Royal Society for Biology, British Association for Cancer Research, European Association for Cancer Research, British Society for Cell Biology, Association for British Science Writers. Sponsors: Wellcome Trust funding for research on transcriptional co-factors in cancer.

Hui ChenView profile

Assistant Professor

• Stem Cells & Developmental Biology
• Embryonic Genome Regulation
• Biological Size Regulation
• +3 more

Hui Chen is an Assistant Professor in the Department of Biological Sciences at the University of South Carolina within the McCausland College of Arts and Sciences . The research focuses on understanding how cellular components orchestrate embryo development at the earliest stages, particularly the regulation of the early embryonic genome for spatiotemporal cell fate specification and novel mechanisms of biological size regulation in development and diseases. University: University of South Carolina College: McCausland College of Arts and Sciences Department: Biological Sciences Academic Rank: Assistant Professor Research Interests span Developmental Biology , Embryonic Genome Regulation , and Biological Size Control . Key areas include elucidating spatiotemporal patterning of zygotic genome activation, studying nuclear size regulation, and investigating how cellular dimensions integrate with differentiation. These studies utilize interdisciplinary technologies and have implications for developmental disorders and cancer. Publications highlight work on transcriptional dynamics in early embryogenesis, nuclear scaling mechanisms, and cancer cell migration. Articles are published in journals such as Current Biology , Developmental Cell , and bioRxiv , with a focus on developmental gene regulation and biomechanical constraints. Labs & Teams : The Chen Lab leverages model embryonic systems and cutting-edge technologies to explore fundamental principles of early development, aiming to inform strategies for addressing developmental disorders and cancer.

Chery A. WhippleView profile

Associate Professor

• Anatomy & Physiology
• Biology
• Environment
• +7 more

Chery A. Whipple is an Associate Professor at Colby-Sawyer College in the School of Arts & Sciences , where she teaches Biology, Microbiology, Genetics, Anatomy & Physiology, and Laboratory Techniques . She joined the faculty in 2017 after 12 years of cancer research at Dartmouth’s Norris Cotton Cancer Center. Education: B.S. in Biology (Lake Erie College), M.S. in Education (University of New Hampshire), Ph.D. in Genetics (University of New Hampshire), Postdoctoral Research (Dartmouth Medical School) Research Interests focus on cancer cell lines , particularly pancreatic and skin cancer , and the interaction between tumor cells and their microenvironment. She also investigates emerging groundwater contaminants using C. elegans and cell lines. Scientific Awards include grants from INBRE and NIH Science Education Partnership Award (SEPA), supporting undergraduate research initiatives and novel science education programs. Advising & Grants : Professor Whipple mentors undergraduate researchers and leads summer research courses via NH-INBRE . Her work on tumor-stromal communication and environmental toxicology is funded by federal and state grants. Labs & Teams : Collaborates with New Hampshire Academy of Science and NH-INBRE , involving students in field studies (e.g., tropical communities in Belize) and laboratory projects.

Patricia A MoweryView profile

Professor

• Biochemistry
• Cancer Biology
• Anti-cancer Agents
• +5 more

Patricia A Mowery is a Professor of Biology at Hobart and William Smith Colleges, where she has been a faculty member since 2007. She holds a Ph.D. in Biochemistry from the University of Wisconsin-Madison and has a multidisciplinary academic background that includes degrees in Sociology from Yale and the University of Chicago. Her research is primarily focused on the development of anti-cancer agents and the biochemical mechanisms underlying cancer cell toxicity. Ph.D., Biochemistry, University of Wisconsin-Madison (2003) B.S., Biochemistry, Indiana University (1997) M.A., Sociology, Yale University (1991) B.A., Sociology, University of Chicago (1989) Her research interests include anti-cancer agents, tubulin polymerization inhibition, protein interactions, and structure-function studies. She collaborates with chemists and molecular modelers to design and evaluate novel compounds that target cancer cell proliferation. Her work combines experimental biology with computational modeling to refine drug candidates for enhanced potency. The trends in her recent publications reflect a sustained focus on medicinal chemistry and cancer therapeutics, particularly in the design and evaluation of indole-substituted furanones and other small molecules that inhibit tubulin polymerization. Her research also extends into plant pathology, where she has studied the molecular mechanisms of Xylella fastidiosa, a bacterium responsible for Pierce’s disease in grapevines. Patricia Mowery actively mentors undergraduate researchers, as evidenced by the numerous student co-authors on her publications. She teaches a variety of courses, including Nutrition, Microbiology, Immunology, and senior seminars in virology and biochemistry. While no formal scientific awards are listed, her consistent publication record and collaborative research efforts highlight her contributions to the field. She has no listed grants in the provided text but maintains an active research program with ongoing publications and student involvement. Her lab emphasizes interdisciplinary collaboration, particularly with organic chemists and computational modelers, to advance the development of novel anti-cancer therapeutics. She is deeply integrated into the academic and research life of the Biology department at HWS.

Joshua D. CurrieView profile

Assistant Professor

• Regenerative Biology
• Developmental Biology
• Cell Biology
• +7 more

Joshua D. Currie is an Assistant Professor in the Department of Biology at Wake Forest University, where he leads the Currie Lab focused on regenerative and developmental biology. His lab is located at Wake Downtown in Winston-Salem, NC, within the Innovation Quarter, adjacent to the Wake Forest School of Medicine and the Wake Forest Institute for Regenerative Medicine (WFIRM), fostering interdisciplinary collaboration. Dr. Currie earned his Ph.D. from the University of North Carolina at Chapel Hill and completed postdoctoral research at the Center for Regenerative Therapies in Dresden, Germany. His research centers on understanding how tissues regenerate, using the Mexican axolotl ( Ambystoma mexicanum ) as a model system. He investigates the spatiotemporal coordination of cells during limb and tail regeneration, particularly the formation and function of the blastema—a mass of progenitor cells that rebuilds missing structures. His lab combines live imaging , CRISPR/Cas9 genome editing , ex vivo cell biology , and single-cell transcriptomics to uncover the molecular and cellular mechanisms of regeneration. A key goal is to compare regenerative processes in axolotls with fibrotic wound healing in mammals to identify therapeutic targets for improving human tissue repair. The recent publications of Dr. Currie reflect a strong trend in regeneration biology , cell dynamics , and molecular control of tissue morphogenesis . His work spans from fundamental cell biological mechanisms in Drosophila to cutting-edge regeneration studies in vertebrates, demonstrating a deep integration of model systems and methodologies. The interdisciplinary nature of his research bridges developmental biology, cell biology, and translational regenerative medicine. Scientific Awards: No awards explicitly mentioned in the text. Dr. Currie advises graduate and undergraduate researchers in his lab, though specific student names are not listed. His lab receives research funding that supports advanced imaging and molecular biology work, likely through federal or private grants, though specific grants are not detailed. He actively recruits new team members and emphasizes core values such as collaboration, rigor, and inclusivity. The Currie Lab is embedded in a vibrant research ecosystem at Wake Forest, with strong ties to regenerative medicine initiatives. The lab’s location in the Innovation Quarter enables close interaction with clinicians and engineers, enhancing the translational potential of their discoveries. The lab also promotes open science through shared resources and protocols.

Gunther WennemuthView profile

Professor

• Reproductive Biology
• Sperm Physiology
• Ion Channels
• +11 more

Prof. Dr. Gunther Wennemuth is a full Professor and Director of the Institute of Anatomy at the University of Duisburg-Essen , Faculty of Medicine, Germany. He leads a research group focused on reproductive biology, immunology, and cancer, with a strong emphasis on molecular mechanisms in sperm physiology and female reproduction. Full Professor, Institute of Anatomy, University of Duisburg-Essen (2013–present) Full Professor, Saarland University (2007–2012) Post-doctoral Research, University of Washington, Seattle (1998–2001) Post-doctoral Research, Philipps-University Marburg (2002–2006) Medical Internship, Philipps-University Marburg (1995–1997) His research interests span sperm physiology , particularly ion and proton channels (e.g., CatSper) regulating motility, hyperactivation, and sperm-egg communication. He employs cutting-edge digital holographic microscopy (DHM) to study 4D sperm trajectories. His work also includes female reproduction (oocyte aging, endometriosis), prostate cancer (microRNAs, neuroendocrine differentiation), and the role of CEACAMs in infection, inflammation, and cancer. His lab integrates photometry, electron microscopy, molecular biology, and protein biochemistry. The publication trends reveal a consistent focus on reproductive biology, with recent high-impact studies on CatSper structure, CEACAM signaling in immunity and cancer, sperm chirality, and environmental impacts on fertility. His work bridges basic science and translational applications, particularly in oncology and infertility. He has been awarded over 4 million euros in grants and has published more than 100 scientific papers. While no formal list of students is provided, his publications include numerous junior researchers and co-authors, suggesting active mentorship. His team includes scientists like Caroline Wiesehöfer and Jaroslaw Dankert. No scientific awards are listed in the provided text.

Tianyan GaoView profile

Professor

• Cancer Biology
• Signal Transduction
• Protein Phosphatases
• +9 more

Tianyan Gao is a Professor in the Department of Molecular and Cellular Biochemistry at the University of Kentucky, where she holds the William A. Marquard Chair in Cancer Research. She is also affiliated with the Markey Cancer Center. Her research focuses on protein phosphatases and their roles in cancer signaling pathways, particularly in colorectal cancer. Ph.D., Northwestern University, Chicago, IL B.S., Beijing Medical University, Beijing, China Postdoctoral Fellow, University of California, San Diego Dr. Gao's research centers on protein phosphorylation and dephosphorylation in cell signaling, with a strong emphasis on the PHLPP family of protein phosphatases. Her lab investigates how PHLPP regulates intestinal epithelial cell proliferation and apoptosis, and its role in suppressing tumorigenesis in colorectal cancer. She has also expanded her work to include PTPRF and mitochondrial regulation of metabolism in cancer. Her studies employ knockout mouse models and organoid systems to explore Wnt signaling, metabolic reprogramming, and chemoresistance. Her recent publications reveal a consistent focus on cancer metabolism, mitochondrial dynamics, and signaling pathways such as RAS/RAF, Wnt, and mTOR. These works highlight her integrative approach linking metabolic regulation with oncogenic signaling in colon and other cancers. William A. Marquard Chair in Cancer Research Dr. Gao has secured sustained research funding and leads a productive laboratory that investigates fundamental mechanisms of cancer progression. Her work has important implications for targeted therapies and chemoresistance. She collaborates extensively with researchers in metabolism, gastroenterology, and cancer biology. Her lab has contributed to understanding how metabolic interactions between adipocytes and cancer cells promote tumor growth. She leads research in multiple areas including mitochondrial retrograde signaling, ER stress, and neurotensin-mediated metabolic regulation. Her team uses advanced models such as genetically engineered mice and patient-derived organoids to study tumor-stroma interactions and stem cell functions in cancer.

• Molecular Pharmacology
• G-Protein Coupled Receptors (GPCRs)
• Metabolic Disorders
• +7 more

Sanja Bosnyak-Gladovic is a Research Fellow at the Neuromedicines Discovery Centre (NDC), Faculty of Pharmacy and Pharmaceutical Sciences, Monash University. Her work focuses on molecular mechanisms underlying metabolic and inflammatory diseases, with a strong emphasis on G-protein coupled receptors (GPCRs) and their role in diabetes, fibrosis, and immune regulation. Her research interests include Molecular Pharmacology , GPCR signaling , metabolic disorders , inflammation , immune cell migration , and organ fibrosis . She utilizes gene knockout models, RNA sequencing, and functional assays to explore therapeutic targets in diabetes and chronic tissue damage. The most recent publications highlight her contributions to understanding GPR21 in glucose homeostasis and immune function, receptor crosstalk in fibrotic pathways, and biased agonism in histamine receptors. These works span journals in pharmacology, endocrinology, nephrology, and immunology, indicating interdisciplinary impact. She actively collaborates with leading researchers in pharmacology and drug discovery, including Arthur Christopoulos, Patrick Sexton, and Roger Summers. Although no formal advising or grant information is listed, her sustained research output over more than a decade reflects deep engagement in translational science.

Jesse MagerView profile

Professor

• Developmental Biology
• Epigenetics
• Genomics
• +12 more

Jesse Mager is a Professor in the Department of Veterinary and Animal Sciences at the University of Massachusetts Amherst, where he also serves as Associate Vice Chancellor for Research Support Services. His research is centered on early mammalian development, with a focus on phenotypic analysis of knockout mouse models generated through the Knockout Mouse Project (KOMP2) and the International Mouse Phenotyping Consortium (IMPC). His research interests include developmental epigenetics, genome imprinting, chromatin remodeling, and gene function during preimplantation and gastrulation stages. He employs RNAi and epigenetic reporter systems to dissect the regulatory mechanisms governing early embryonic development. His lab has characterized over 200 knockout lines, identifying critical developmental checkpoints and epigenetic regulators. His recent publications reveal essential roles for genes involved in transcription (TAFs, POLR1D), RNA processing (Exosc1/2), chromatin regulation (RBBP4, KANSL3), and organelle function (Borcs6) in early embryogenesis. These studies highlight conserved mechanisms underlying mammalian development and disease. ZC3H4—a novel Cys-Cys-Cys-His-type zinc finger protein—is essential for early embryogenesis in mice Overlapping peri-implantation phenotypes of ZNHIT1 and ZNHIT2 despite distinct functions during early mouse development TATA-binding associated factors have distinct roles during early mammalian development Protein phosphatase 1 regulatory subunit 35 is required for ciliogenesis, notochord morphogenesis, and cell-cycle progression during murine development Loss of POLR1D results in embryonic lethality prior to blastocyst formation in mice Dr. Mager mentors several graduate and undergraduate students and teaches courses in genetics, developmental biology, and scientific communication. He actively collaborates with international consortia and shares data to advance functional annotation of the mammalian genome. His lab, located in the Integrated Sciences Building, is supported by institutional and collaborative research funding, enabling high-throughput phenotypic screening and molecular analysis of early embryonic lethality in mice.