Swiss Federal Institute of Technology in LausanneSwitzerland
Sara Gallini is an Assistant Professor at EPFL, leading the Gallini Lab within the ISREC Department of the School of Engineering (SV). Her research focuses on understanding how healthy and oncogenic cells compete in skin epithelium, aiming to identify therapeutic targets for skin cancer prevention. She holds a Tenure Track position and teaches in the Life Sciences Engineering program. Her lab employs advanced in vivo imaging and single-cell analysis techniques. Education details are not explicitly provided, but her career includes a postdoctoral fellowship with the HFSP. Her research integrates molecular, cellular, and systems-level approaches to study cancer initiation and tissue homeostasis, particularly in injury-driven dynamics. Lab Members: Includes PhD student Mustafa Öztürk and technical staff Mélanie Sipion. Key Research Themes: Oncogenic cell competition, epidermal regeneration, EGFR/ERK signaling, and therapeutic target discovery. Her lab collaborates with clinical teams and uses models like mouse skin to study tumor suppression mechanisms. Future work aims to leverage healthy cell dynamics for cancer treatment strategies. Contact: SV 2527 office, +41216936764, sara.gallini@epfl.ch .
Konstantinos Anastassiadis is a Professor at the Center for Molecular and Cellular Bioengineering (CMCB) of Dresden University of Technology , leading the Stem Cell Engineering group at the Biotechnology Center (BIOTEC) . His research focuses on unraveling molecular pathways regulating stem cell self-renewal and lineage commitment, with a strong emphasis on genetic engineering tool development and epigenetic mechanisms during cellular reprogramming. The lab utilizes mouse and human embryonic stem cells, neural stem cells, mesenchymal stromal cells, and induced pluripotent stem cells (iPSCs) in their investigations. Core Research Areas: Molecular regulation of stem cell fate Epigenetic mechanisms (e.g., UTX/UTY histone demethylases) Genetic engineering tool development (Flp, Dre, Vika recombinases, CRISPR protocols) Conditional immortalization systems for rare cell expansion Publications highlight his contributions to understanding: Role of histone methyltransferases (MLL1, MLL2, Setd1b) in hematopoiesis and cancer Epigenetic regulation during mouse development and spermatogenesis Genetic tools for protein tagging, transposon-mediated BAC transgenesis Interactions between stem cells and niche microenvironments Transcriptional and mechanical markers during reprogramming Collaborations span immunology , developmental biology , and bioinformatics . The lab actively participates in teaching activities at CMCB and maintains a focus on translational applications of stem cell research.
Michael Lampson is Professor of Biology at the University of Pennsylvania's School of Arts and Sciences, with secondary appointments in the Department of Cell and Developmental Biology. He serves as faculty in the Cell and Molecular Biology (CAMB) and Biochemistry and Molecular Biophysics (BMB) Graduate Groups, and is affiliated with the American Society for Cell Biology (ASCB). Ph.D., Cornell University, Weill Medical College, 2002 AB, Harvard College, 1994 Dr. Lampson's research program focuses on fundamental mechanisms of chromosome biology, with particular emphasis on cell division, centromere inheritance, and meiotic drive. His lab investigates how selfish genetic elements can violate Mendel's First Law through meiotic drive, the stability of centromere chromatin through the germline, and the role of repetitive satellite DNA in chromosome segregation. Using innovative approaches including mouse model systems, optogenetic tools, and biochemical techniques, his work bridges cell biology, genetics, and evolutionary biology to address questions with implications for reproductive biology, cancer, and genetic inheritance. Analysis of Dr. Lampson's recent publications reveals a strong focus on the intersection of centromere biology, meiotic drive, and chromosome segregation mechanisms. His work increasingly incorporates computational approaches alongside experimental systems to study evolutionary aspects of centromere function. The research demonstrates consistent innovation in methodology, particularly in developing optogenetic tools for precise manipulation of cellular processes. Key themes include the role of satellite DNA variation, mechanisms of non-Mendelian inheritance, and the stability of chromatin structures through cell division and development. Searle Scholar Award American Association for the Advancement of Science (AAAS) fellow Dr. Lampson's research is supported by multiple NIH grants including from NIGMS, NHGRI, NICHD, and NCI, as well as University of Pennsylvania funding sources including the University Research Foundation, Abramson Cancer Center, and several specialized research centers. He collaborates extensively with researchers across disciplines, including Ben Black (Biochemistry), Dennis Discher (Chemical Engineering), Dave Chenoweth (Chemistry), and Roger Greenberg (Cancer Biology), reflecting the interdisciplinary nature of his work. His lab has trained numerous graduate students and postdocs who have gone on to successful careers in academia and industry. The Lampson Lab maintains state-of-the-art facilities for cell biological, genetic, and biochemical research, with specialized equipment for live-cell imaging, optogenetic manipulation, and mouse genetics. The lab fosters a collaborative environment that bridges molecular, cellular, and evolutionary perspectives on chromosome biology.
Vilhelm Bohr is an Affiliate Professor at the Department of Cellular and Molecular Medicine , University of Copenhagen, affiliated with the Molecular Aging Program and Center for Healthy Aging . His research explores the interplay between DNA maintenance , mitochondrial biology , and aging , particularly in age-associated neurodegeneration and Alzheimer’s disease. Research Interests include: Molecular mechanisms linking NAD + metabolism to mitochondrial dysfunction and neurodegeneration Role of tau pathology in DNA damage and mitochondrial stress Impact of Aprataxin (APTX) and RECQL4 helicase defects on mitochondrial DNA integrity Pharmacological strategies to improve mitochondrial health via autophagy modulation Publications (2025-2024) span topics like NAD + biosynthesis, Werner/Rothmund-Thomson syndromes, tau nuclear functions, and mitochondrial turnover, with high citations and media attention. Collaborations extend to clinical tumor samples and CRISPR-based disease models.
Silvia Santos is a Group Leader at the Francis Crick Institute, leading the Quantitative Stem Cell Biology Lab since January 2018. Her research focuses on understanding cell decision-making during transitions, specifically cell division and differentiation in early development using human embryonic stem cells. She combines experimental techniques with theoretical approaches, including advanced microscopy, genomics, and computational modeling. Education and Career: PhD in Molecular and Cell Biology from EMBL-Heidelberg (2008), followed by postdoctoral training at Stanford University (2009-2014). She held an MRC Career Development Award at Imperial College London (2014-2017) before joining the Crick. Her work emphasizes interdisciplinary methods to study cellular processes in health and disease. Research Interests: Spatial-temporal control in cell decisions, stem cell differentiation, cell cycle regulation, and modeling embryonic development. She advocates for women in science and mentorship programs for early-career researchers. Key Achievements: Recipient of Marie Curie E-Star, EMBO, and HFSP fellowships. Recognized with the BioModels’ Model of the Year 2023 for contributions to systems biology. Her lab develops models like gastruloids to study embryonic development. Grants and Mentorship: Supported by MRC and other grants. Committed to fostering excellence in training and mentorship, previously chairing mentorship initiatives at Imperial College London. Labs and Teams: Quantitative Stem Cell Biology Lab at the Crick, collaborating with interdisciplinary teams on projects involving proteomics, genomics, and high-throughput screening.
Jianhua Xing is an Associate Professor in the Department of Physics & Astronomy at the University of Pittsburgh , affiliated with the Dietrich School of Arts and Sciences . His research focuses on applying physics-based approaches to study biological systems, particularly cell phenotypic transitions (CPTs) and their underlying dynamics. He integrates quantitative single-cell measurements with computational and theoretical analyses to understand how cells transition between stable states. Key research areas include: Nonequilibrium systems and rate theories for biological transitions Single-cell trajectory analysis and live-cell imaging Epithelial-mesenchymal transition (EMT) dynamics Gene regulatory networks and stochastic processes Biological applications of dynamical systems theory Recent work highlights the coupling between EMT and cell cycle arrest, leveraging machine learning frameworks (e.g., LivecellX ) for high-resolution imaging analysis. His lab also explores chromosomal dynamics and mechanotransduction in stem cell aging. Publications emphasize data-driven modeling and theoretical insights, with contributions to frameworks like GraphVelo and Graph-Dynamo for inferring cellular state transitions. Collaborative efforts bridge physics, biology, and computational science to address fundamental biological questions. No awards or grants are explicitly listed in the provided texts. His research group focuses on advancing systems biology through interdisciplinary methods, with a lab dedicated to quantitative analysis of cellular processes.
Eduardo Rocha is a Professor and Head of the Microbial Evolutionary Genomics laboratory at the Institut Pasteur, within the Department of Genomes and Genetics. His research integrates bioinformatics, molecular evolution, and genomics to understand bacterial genome organization and dynamics, particularly focusing on mobile genetic elements and their role in adaptation and antibiotic resistance. His research interests include microbial evolutionary genomics, genome organization, horizontal gene transfer, mobile genetic elements (plasmids, phages, integrons), bacterial pathogen evolution, and computational biology. His work lies at the intersection of molecular evolution, population genetics, and molecular epidemiology, with strong translational implications for understanding antimicrobial resistance and infectious disease emergence. The recent publications highlight a consistent focus on mobile genetic elements, genome plasticity, and bacterial adaptation. Key themes include the role of integrons and CRISPR-Cas systems in bacterial immunity, plasmid-mediated spread of antibiotic resistance, phage-plasmid interactions, and the development of bioinformatics tools for microbial genomics. These works frequently appear in high-impact journals such as Science , Nature Microbiology , and PLoS Biology , reflecting significant contributions to the field. Eduardo Rocha leads multiple funded research projects, including ERC-2011-StG EVOMOBILOME, ANR Magisbac, and ANR SHAPE. He has developed and maintains several widely used bioinformatics software tools: IntegronFinder, MacSyFinder, PanACoTA, SatelliteFinder, CapsuleFinder, TXSScan, and others. He mentors a large team of PhD students, postdoctoral researchers, and engineers, and has supervised numerous former students who now hold independent research positions worldwide. Eduardo Rocha has received research funding from major agencies including the European Research Council (ERC) and the French National Research Agency (ANR). His work is central to the LabEx IBEID and the INCEPTION convergence program, where he serves on the steering committee, promoting interdisciplinary research in infectious disease emergence. His laboratory, part of the Genomes and Genetics department, actively contributes to microbial evolutionary genomics through both methodological development and biological discovery. The team participates in networks such as Phages.fr, GDR BIM, and GDR AIEM, reinforcing its collaborative and integrative approach.
Dr. Julia Kamenz is an Assistant Professor (Rosalind Franklin fellow) at the University of Groningen's Faculty of Science and Engineering, where she leads research in the Molecular Systems Biology group within the Groningen Biomolecular Sciences and Biotechnology Institute (GBB). Her work focuses on understanding the molecular mechanisms that regulate cell cycle progression and cell division. Dr. Kamenz received her undergraduate training in Biochemistry at the University of Tuebingen, completed her PhD at the Friedrich Miescher Laboratory of the Max Planck Society under Dr. Silke Hauf (defended February 2015 with highest honors), and conducted postdoctoral research at Stanford University with Prof. James E. Ferrell. Her PhD work was supported by a Boehringer Ingelheim Fonds fellowship, and her postdoc was funded by a German Research Foundation (DFG) Postdoctoral Fellowship. Her research expertise spans cell cycle regulation and dynamics, post-translational modifications, Xenopus laevis model systems, and live cell microscopy. Dr. Kamenz investigates how kinases and phosphatases intricately regulate cell proliferation and division, with particular interest in the molecular mechanisms that ensure faithful chromosome segregation during mitosis. Her recent work has revealed novel insights into mitotic checkpoint signaling, particularly in early embryonic development where these checkpoints appear to function differently than in somatic cells. Dr. Kamenz's publication record demonstrates a strong focus on the dynamics of cell cycle transitions, with recent papers appearing in high-impact journals including Nature, The Journal of Biological Chemistry, and The Journal of Cell Biology. Her research integrates experimental biochemistry, live-cell imaging, and computational modeling approaches to understand complex regulatory networks. ERC Starting Grant (November 2022) NWO Vidi Grant (July 2021) Mansour Postdoctoral Travel Award (2019) Dr. Kamenz has secured significant research funding including an ERC Starting Grant (€1.5 million) and an NWO XS grant (€50,000) for her project "What limits mitotic checkpoint signaling in the early embryo?" Her research contributes to understanding fundamental biological processes with implications for developmental biology and cancer research. She collaborates extensively within the University of Groningen and with international partners, particularly in the areas of cell cycle research and biophysical approaches to biological problems. Dr. Kamenz leads a research group focused on cell cycle regulation within the Molecular Systems Biology division of the Groningen Biomolecular Sciences and Biotechnology Institute. Her lab combines biochemical approaches using Xenopus egg extracts with live-cell imaging and computational modeling to dissect the molecular mechanisms controlling cell division.
John Diffley is a Principal Group Leader and Associate Research Director at The Francis Crick Institute in London, UK, where he leads research on DNA replication mechanisms. His work focuses on understanding how cells precisely duplicate their DNA during cell division and how errors in this process contribute to cancer development. Diffley obtained his PhD from New York University in 1985 and completed postdoctoral training with Bruce Stillman at Cold Spring Harbor Laboratory until 1990. He established his research group at the Clare Hall Laboratories (originally Imperial Cancer Research Fund, then Cancer Research UK) before moving to The Francis Crick Institute in 2015. His research spans DNA replication initiation, cell cycle control, replication fork checkpoints, and epigenetic inheritance. Diffley's lab has pioneered methods to reconstitute chromatin replication using purified proteins, providing unprecedented insights into chromosome biology. His team combines genetics, cell biology, and biochemistry to study the molecular 'machines' that copy DNA in yeast and human cells. Analysis of Diffley's recent publications reveals a strong focus on structural mechanisms of DNA replication, particularly using cryo-EM to visualize replication machinery. His work examines helicase loading and activation, replication fork stability under stress, and the connection between replication errors and cancer development. The research spans model organisms to human cells, with increasing emphasis on structural approaches in recent years. FRS (Fellow of the Royal Society) FMedSci (Fellow of the Academy of Medical Sciences) Diffley actively mentors a diverse team of postdoctoral researchers and PhD students, investigating various aspects of DNA replication. His lab has received substantial funding to support their work on replication mechanisms, with projects spanning basic biochemical reconstitution to studies of replication errors in cancer contexts. The lab maintains multiple technical platforms including structural biology, biochemistry, and cell biology approaches. His research group operates within The Francis Crick Institute's collaborative environment, utilizing shared facilities for structural biology, microscopy, and genomics to advance understanding of DNA replication mechanisms and their implications for genome stability and disease.
Kara McKinley is an Assistant Professor of Stem Cell and Regenerative Biology at Harvard University , joining the department in 2021. She is a Principal Faculty member at the Harvard Stem Cell Institute , an Associate member of the Broad Institute of MIT and Harvard , and a Freeman Hrabowski Scholar at the Howard Hughes Medical Institute . Her research focuses on the regenerative capacity of the human uterus , particularly the endometrium, which undergoes ~400 cycles of tissue remodeling, shedding, and repair during the reproductive lifespan. Using rodent models , genetic, molecular, and live microscopy tools, her lab investigates cellular and molecular mechanisms of regeneration, defects leading to diseases like endometriosis, and applications in regenerative medicine . Her work also explores cell division , centromere biology , and CRISPR genome engineering . Current research trends in her publications include epithelial zonation in the small intestine , mechanisms of endometrial regeneration , macropinocytosis in Hydra , and academic mentorship strategies . Her studies span cellular biomechanics , mitotic regulation , and translational approaches for tissue repair. NIH Director’s New Innovator Award (terminated in 2025 litigation with federal government) Freeman Hrabowski Scholar (Broad Institute) Kara mentors Harvard undergraduates, graduate students, and postdoctoral fellows through rotations and research opportunities. Her lab is based at Harvard’s Bauer 306 and advocates for gender equity in life sciences faculty via the Leading Edge initiative. Funding includes a now-terminated NIH New Innovator grant aimed at menstrual health research.
Dr. Philippe Campeau is an Associate Clinical Professor in the Department of Pediatrics at the Faculty of Medicine, Université de Montréal. He is affiliated with CHU Sainte-Justine, a major pediatric hospital in Montreal, Quebec, where he works in the Medical Genetics Service. His clinical and research work focuses on genetic disorders affecting children, particularly in the areas of skeletal development and neurogenetics. Dr. Campeau obtained his Doctorate in Medicine from Laval University in Quebec (1998-2003) followed by specialty training in medical genetics at McGill University (2003-2008). He completed postdoctoral training at Baylor College of Medicine (2008-2013), which further developed his expertise in genetic research methodologies. His primary research interests include bone dysplasias , skeletal dysplasias , epilepsy , and epigenetic diseases . Dr. Campeau's laboratory identifies disease-causing genes, deciphers disease pathophysiology, and works to improve the management of children affected by these conditions. His work encompasses exome analysis , functional studies with cell lines and mouse models , and investigations into urea cycle abnormalities . He has made significant contributions to understanding genetic causes of conditions such as Genitopatellar syndrome (KAT6B), osteopetrosis, dysosteosclerosis (SLC29A3), osteogenesis imperfecta, early-onset osteoporosis (WNT1), Yunis-Varón syndrome (FIG4), and DOORS syndrome (TBC1D24). Dr. Campeau's publication record demonstrates a strong trajectory in medical genetics research, with numerous high-impact publications spanning from fundamental genetic discovery to translational research. His work spans skeletal disorders, neurodevelopmental conditions, and epigenetic mechanisms. Recent publications indicate an expanding focus on chromatin modifiers, DNA methylation patterns, and spliceosome function in neurodevelopmental conditions, reflecting the evolution of his research interests toward more complex molecular mechanisms. Dr. Campeau has received several research grants in recent years (6 starting in 2014) from organizations including the Fonds de la recherche en santé du Québec, Canadian Institutes of Health Research, and Fondation Grand Défi Pierre Lavoie. While specific students are not mentioned in the available information, as a clinical professor, he mentors medical students, residents, and research trainees in the Department of Pediatrics. His research is conducted as part of the 'Musculoskeletal Diseases and Rehabilitation' axis at CHU Sainte-Justine Research Center, where he collaborates with international research teams to identify disease-causing genes and develop better management strategies for children with genetic disorders.
Ueli Grossniklaus is an Ordinary Professor at the University of Zurich within the Faculty of Mathematical and Natural Sciences , affiliated with the Department of Plant and Microbiology . His work focuses on plant developmental biology, particularly epigenetic and genetic mechanisms governing reproduction and adaptation. Key Courses: Epigenetics, Plant Biology Workshop, Group Seminars on Current Research Laboratory Techniques: Advanced methods in plant cell mechanics, transcriptomics, and genome editing Research Interests span plant epigenetics, reproductive biology, and the interplay between environmental stress and genetic regulation. He investigates: Mechanistic control of gametogenesis and fertilization Epigenetic contributions to plant adaptation Evolutionary implications of asexual reproduction Biophysical forces in plant cell growth Publication Trends (2025–2018) reveal expertise in: Arabidopsis and fern model systems Epigenetic regulation (DNA methylation, histone dynamics) Apomixis and hybrid seed failure mechanisms Biomechanics of pollen tubes and carnivorous plants Genome editing tools (CRISPR) and long-read sequencing Scientific Collaborations include interdisciplinary projects on: Microfluidic devices for plant cell analysis Gene drive ecology and ethics 3D imaging of plant reproductive structures Advising and Grants focus on mentoring through research internships in developmental biology, genetics, and systems biology. His lab engages in: Epigenetic response to environmental stress Cell wall mechanics in reproduction Computational modeling of plant growth Laboratory Teams integrate plant biologists, bioengineers, and computational scientists to study: Mechanistic gene regulation Evolutionary developmental biology Microrobotics for cellular force measurement
Scott Forth is an Associate Professor in the Department of Biological Sciences at Rensselaer Polytechnic Institute's School of Science. He specializes in biophysics, focusing on microtubule networks in cell division and neuronal development. Ph.D. in Physics from Cornell University (2009) B.S. in Physics and B.M. in Music Performance from Oberlin College (2002) Postdoctoral Fellow at Rockefeller University (2010-2016) His research combines optical trapping and fluorescence microscopy to study how forces are transmitted across biopolymer networks. Key areas include: Mechanics of mitotic microtubule networks PRC1-mediated force resistance in cell division Kinesin motor protein dynamics Single-molecule biophysical methods Neuronal cytoskeleton organization Recent work analyzes force generation in reconstituted microtubule bundles and mechanical roles of proteins like PRC1 and kinesin-5. Scientific Awards Ruth Kirschstein National Research Service Award (NIH postdoctoral F32) Rensselaer School of Science Outstanding Teacher Award Rensselaer School of Science Early Career Research Award Biophysical Society Early Career Award (Motility and Cytoskeleton Subgroup) Dr. Forth's lab studies how nanometer-scale proteins coordinate to create micron-scale cellular mechanics. Current projects focus on microtubule network organization during cell division and neuronal development.
Hajime Murakami is an Advanced Research Fellow at the University of Aberdeen's School of Medicine, Medical Sciences and Nutrition, where he conducts cutting-edge research on meiotic recombination mechanisms. His work focuses on understanding how cells manage the complex process of DNA double-strand break formation and repair during meiosis, with implications for human fertility and chromosome disorders. Dr. Murakami's research interests center on the molecular mechanisms of meiotic recombination, particularly the role of DNA double-strand breaks (DSBs) in chromosome segregation. His laboratory investigates how proteins like Hop1 and Red1 function as 'manager proteins' that direct the DNA 'scissors' to appropriate chromosomal locations, ensuring proper recombination while preventing errors that could lead to miscarriage or congenital syndromes. His work primarily uses yeast as a model system, which shares fundamental meiotic mechanisms with humans. Analysis of Dr. Murakami's publication record reveals a consistent focus on the molecular regulation of meiotic recombination across his career. His research has progressively uncovered sophisticated control mechanisms that ensure accurate chromosome segregation, with particular emphasis on how cells manage DNA break formation across chromosomes of different sizes. His work spans fundamental molecular mechanisms to potential clinical applications in reproductive medicine. Dr. Murakami has received significant recognition for his work, most notably a Medical Research Council (MRC) Career Development Award, which supports his ongoing research into the molecular basis of meiotic recombination. As an active researcher accepting PhD students in Biomedical Sciences, Dr. Murakami continues to advance our understanding of fundamental genetic processes that underlie human reproductive health. His laboratory at the Institute of Medical Sciences on Foresterhill Campus employs yeast genetics and molecular biology approaches to investigate the critical processes that ensure proper chromosome segregation during gamete formation.
Cheryl Walker, Ph.D., is a Professor in the Departments of Molecular and Cellular Biology, Medicine, and Molecular and Human Genetics at Baylor College of Medicine. She serves as Director of the Center for Precision Environmental Health and Co-Leader of the Chromatin Biology Program at the Dan L Duncan Comprehensive Cancer Center. Her research focuses on gene-environment interactions, epigenomics, and the molecular mechanisms underlying diseases such as cancer, fibroids, and non-alcoholic fatty liver disease (NAFLD). Key areas include the role of chromatin remodelers like SETD2 in genomic stability and their dual functions in cytoskeletal dynamics. She has pioneered studies on how early-life environmental exposures, such as endocrine-disrupting chemicals (EDCs), reprogram the epigenome to increase disease susceptibility later in life. Dr. Walker’s work is funded by NIH and DOD grants, including leadership of the TaRGET II Consortium for environmental epigenomics. Her lab employs cutting-edge technologies like ChIP-seq and RNA-seq to study epigenetic reprogramming. Notable contributions include discoveries linking SETD2 methylation to microtubule stability and genomic integrity, and identifying epigenetic signatures of environmental exposures in health disparities research. Education: Ph.D. in Molecular Biology Affiliations: Baylor College of Medicine, Gulf Coast Center for Precision Environmental Health Her awards include election to the National Academy of Medicine and fellowships in the American Association for the Advancement of Science (AAAS) and American Thoracic Society (ATS). The lab actively collaborates on translational projects, including biomarker development and disaster-related health studies following events like Hurricane Harvey. Key Research Themes: Epigenetic drivers of cancer and fibrosis Environmental epigenomics and disease risk Chromatin-cytoskeleton cross-talk in disease
