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Steven C. GrambowView profile

Associate Professor

• Biostatistics
• Clinical Research Education
• Artificial Intelligence in Academic Workflows
• +3 more

Steven C. Grambow is an Associate Professor and Associate Chair of Education in the Department of Biostatistics & Bioinformatics at Duke University School of Medicine. He serves as Director of Duke’s Clinical Research Training Program (CRTP) and Co-Director of the Duke Clinical and Translational Science Institute (CTSI) Workforce Development Pillar. With over two decades of experience in graduate education, he has trained more than 1,000 physician-scientists in statistical methods while developing innovative programs for clinical research education across various delivery formats. His work focuses on creating pathways into clinical and translational research through partnerships with institutions like North Carolina Central University and Durham Technical Community College. Grambow actively explores AI integration into biostatistical workflows and leads initiatives in faculty development, active learning models, and cross-disciplinary collaboration frameworks. As a collaborative statistical scientist, his research spans observational studies, randomized trials, and epidemiologic investigations addressing public health challenges including amyotrophic lateral sclerosis (ALS), post-traumatic stress disorder (PTSD), and cardiovascular risk reduction. His recent publications highlight innovations in biostatistical education, AI applications, and community-engaged research models. Scientific Awards: American Statistical Association teaching honors Duke University teaching honors Grambow has secured significant grants from NIH, Department of Defense, and University of Colorado-Denver for projects spanning statistical methods in cardiovascular disease research, patient-focused drug development resources, and multi-component lifestyle interventions. He actively mentors through Duke’s educational programs and leads quantitative collaboration units in academic healthcare settings.

Adin-Cristian AndreiView profile

Professor

• Biostatistics
• Data Science
• Machine Learning
• +9 more

Dr. Adin-Cristian Andrei is a Professor in the Department of Biostatistics and Informatics at Northwestern University Feinberg School of Medicine. He maintains strong affiliations with the Center for Diabetes and Metabolism, Institute for Augmented Intelligence in Medicine, and the Northwestern University Clinical and Translational Sciences Institute (NUCATS). Dr. Andrei's educational background includes: BS from University of Bucharest (1998) MS from Michigan State University (2000) PhD from University of Michigan (2005) As a biostatistician and data scientist, Dr. Andrei specializes in applying machine learning and computationally-intensive methods to large-scale medical research. His methodological expertise encompasses propensity score-based causal inference, nonparametric survival analysis, recurrent event modeling, health-related quality-of-life assessments, and hierarchical Bayesian approaches to multiple testing problems. His work bridges statistical theory with practical clinical applications across diverse medical specialties. His recent publications demonstrate strong interdisciplinary collaboration, particularly in cardiology, oncology, and critical care medicine, with emphasis on developing sophisticated analytical approaches to complex clinical questions using real-world health data. Dr. Andrei has received multiple teaching honors including: IPHAM PPH Teacher of the Year Award Finalist (2020) IPHAM PPH Teaching Excellence Award (2019) Top Performance Award from the Journal of Thoracic and Cardiovascular Surgery editorial board (2017) He serves in significant editorial roles including Associate Statistical Editor for the Journal of Respiratory and Critical Care Medicine and Statistician for the Journal of the American College of Surgeons. Dr. Andrei previously chaired the 2019 Joint Statistical Meetings and represents the Statistical Learning and Data Science section on the American Statistical Association Council of Sections. His professional memberships span both statistical and computing disciplines, including the International Society for Clinical Biostatistics, Association for Computing Machinery, and American Statistical Association, reflecting his interdisciplinary approach to medical data science.

Bradley D AllenView profile

Assistant Professor

• Medical Imaging
• Cardiovascular Diseases
• Lung Cancer
• +6 more

Bradley D Allen is an Assistant Professor in the Department of Radiology at Northwestern University Feinberg School of Medicine. He serves as Chief of Cardiovascular and Thoracic Imaging and is board-certified in Diagnostic Radiology by the American Board of Radiology. MD (2011) and MS (2015) from Northwestern University Feinberg School of Medicine Completed postgraduate training in Internal Medicine, Diagnostic Radiology, and Cardiovascular Imaging His research focuses on advancing cardiovascular and thoracic magnetic resonance imaging (MRI) techniques to improve disease diagnosis and treatment. Key areas include quantitative MRI, 4D flow imaging, hemodynamics, and applications in aortic aneurysms, lung cancer, and heart transplants. Recent publications highlight his work in applying 4D flow MRI to type B aortic dissection, Covid-19 vascular effects, automated MRI pipelines, and cardiac allograft monitoring. His awards include the Society of Cardiovascular Magnetic Resonance Fellowship (2023), multiple reviewer accolades from the Journal of Cardiovascular Magnetic Resonance, and recognition as Research Mentor of the Year (2022). Co-chair, American Heart Association CVRI Early Career Committee (2024–Present) Editorial Board Member, Canadian Association of Radiologists Journal (2025–Present) Member, American College of Radiology Cardiothoracic Committee (2022–Present)

• Sports Sciences
• Sports Management
• Physical Education
• +7 more

Prof. Dr. İlhan TOKSÖZ is a Professor and currently serves as the Department Head of Sports Management Sciences at Trakya University's Faculty of Sports Sciences. He has held various academic and administrative positions at Trakya University since 1985, including Founding Director of the School of Physical Education and Sports (16 years), Director of the Kırkpınar and Values Research and Application Center, and Member of the University Senate. He is also actively involved with the Turkish National Olympic Committee, serves on the Boards of Directors of federations affiliated with the Ministry of Sports, and works as a consultant for international universities. His educational background includes: Bachelor's Degree (1984) - Marmara University, Atatürk Faculty of Education Master's Degree (1988) - Marmara University Institute of Social Sciences (Thesis: Determination of Aerobic Capacities of Male University Students) PhD (1992) - Marmara University Health Sciences Institute (Thesis: A Study of the Relationship of Lipoproteins with Training on Various Sports) Post Doctorate (2006) - Kadir Has University Sports Law Research and Application Center Bachelor's Degree (2020) - Anadolu University Health Management Prof. Toksöz's research spans sports management, physical education, sports psychology, recreation studies, and traditional Turkish sports. His work bridges theoretical knowledge with practical applications in sports administration, athlete development, and community recreation programs. He has made significant contributions to understanding Kırkpınar Oil Wrestling as cultural heritage and has published extensively on sports biomechanics, exercise physiology, and recreation management. His research often focuses on practical applications for improving athletic performance and developing effective sports management strategies across Balkan countries. His publication record shows a consistent focus on practical sports science applications, with recent articles emphasizing mindfulness in sports education, recreation's impact on quality of life, and traditional Turkish sports. His earlier works focused more on physiological assessments of athletes in various sports including handball, wrestling, and tennis. Throughout his career, he has maintained a strong connection between academic research and practical sports applications. Prof. Toksöz has received several prestigious awards including the International Publication Incentive Award (2011) and multiple appreciation certificates from governmental institutions. He has served as an advisor for 44 completed postgraduate theses and has been involved in numerous research projects, including the Balkan Sports Games Project and comparative studies of higher education systems in the Balkans. He has also served as editor for multiple journals and as scientific committee member for numerous international conferences. As a founding figure in sports education at Trakya University, Prof. Toksöz has established research centers, organized international symposiums on Kırkpınar wrestling, and contributed to sports policy development at national and international levels. His leadership in establishing the Kırkpınar and Values Research and Application Center demonstrates his commitment to preserving traditional Turkish sports culture while advancing modern sports science.

Brenda OgleView profile

Professor

• Cardiac Tissue Engineering
• 3D Bioprinting
• Stem Cell Differentiation
• +6 more

Brenda Ogle is a Professor in the Department of Biomedical Engineering at the University of Minnesota's College of Science and Engineering. She leads the System Regeneration Lab, where her research focuses on cardiac tissue engineering, stem cell differentiation, and advanced 3D bioprinting technologies. Her work bridges multiple disciplines including stem cell biology, extracellular matrix science, and engineering principles to develop novel approaches for cardiovascular regeneration. Dr. Ogle's research interests primarily center on understanding the mechanisms that govern stem cell fate, particularly in the context of the cardiovascular system. Her lab is pioneering 3D bioprinting for cardiac tissue engineering, creating complex model systems that go beyond simple geometric shapes. Key areas of investigation include the role of extracellular matrix proteins in guiding stem cell differentiation, the development of novel tools for analyzing stem cell behavior, and the delivery of stem cells or associated progeny to the body. Her work has led to breakthroughs in creating patch-like structures with micron-scale features that support cardiac cell organization and can be adhered to failing hearts. Dr. Ogle's research has resulted in significant scientific contributions, including the development of unique bioink formulations coupled with multiphoton-based 3D printing to create chambered heart structures based on digital templates. These engineered tissues can sustain flow profiles and exhibit pressure-volume dynamics characteristic of the native heart, making them valuable for studying cardiac disease progression and testing drug efficacy. Her work has received recognition including an NIH R01 award for Epicardial Regulation of Myocardial Function and being named a BMES Fellow. NIH R01 Awarded, Epicardial Regulation of Myocardial Function BMES Fellow (2021) Dr. Ogle mentors a diverse team of researchers including postdoctoral associates, graduate students, and undergraduate researchers. Her lab has produced numerous PhD graduates who have gone on to successful careers in academia and industry. Current research projects in her lab include heart organoid formation using hiPSC-derived cardiomyocytes, investigation of hypertrophic cardiomyopathy mechanisms, cardiomyocyte maturation studies, and development of ECM-based bioinks for cardiac constructs. The lab is also working on creating integrated platforms for high-throughput cardiac organoid production and developing models to study the impact of radiation exposure on cardiac function.

• Cardiovascular Inflammation
• Atherosclerosis
• Immunotherapy
• +3 more

Claudia Monaco is a Professor of Cardiovascular Inflammation at the Kennedy Institute of Rheumatology, University of Oxford . Her research focuses on the intersection of inflammation and cardiovascular diseases, particularly atherosclerosis. Institution: University of Oxford Department: Cardiovascular Research Academic Rank: Professor Her work investigates molecular mechanisms in atherosclerosis, including roles of interferon regulatory factors , matrix metalloproteinases , and immunotherapy . Recent publications highlight advancements in spatial transcriptomics and aging-related cardiovascular interventions. Collaborative studies explore TGF-β2 activation in diabetic atherosclerosis and inflammatory regulation by B regulatory cells . Her lab employs proteomic profiling to identify disease-specific biomarkers in smooth muscle cells.

• Computational Genomics
• Single-Cell Genomics
• Immunology
• +3 more

Dr. Stephen Sansom serves as Associate Professor and Group Leader of the Computational and Single Cell Genomics Group at the University of Oxford's Kennedy Institute. His work bridges computational biology with immunology to decode inflammatory disease mechanisms through advanced genomic approaches. His academic foundation includes a BSc (Hons) in Biochemistry from the University of Dundee (2001) followed by a DPhil in Developmental Biology through the Wellcome Trust 4-year PhD programme at the University of Cambridge. Postdoctoral research at the Gurdon Institute with Dr. Rick Livesey established his expertise in genomic analysis of neural development. Dr. Sansom's research centers on computational genomics of immune processes, particularly central tolerance mechanisms and inflammatory disorders. His group pioneers single-cell genomic methodologies to dissect cellular heterogeneity in conditions like inflammatory bowel disease, rheumatoid arthritis, and atherosclerosis. Key innovations include developing frameworks for analyzing promiscuous gene expression in thymic epithelia and deconvoluting monocyte responses in immune-mediated diseases through collaborative projects with experimental immunologists. Analysis of his recent publications reveals dominant themes in macrophage biology during atherosclerosis progression, B/T cell dynamics in viral infections (including influenza and COVID-19), and stromal cell contributions to joint destruction in arthritis. His work consistently identifies novel cellular states and molecular networks driving pathogenesis, with strong emphasis on translational relevance for therapeutic targeting. Supported initially by an MRC Career Development Fellowship in Chris Ponting's CGAT program, Dr. Sansom now directs the Computational Genomics team he established at the Kennedy Institute in 2014. His collaborative model integrates computational expertise with wet-lab immunology across multiple Oxford research groups. The Sansom Group operates as the Computational and Single Cell Genomics Group within the Kennedy Institute, maintaining specialized pipelines for high-dimensional genomic data analysis. Current efforts focus on scaling single-cell multi-omics approaches to track immune cell evolution during chronic inflammation and infection.

• Air Pollution
• Particulate Matter Source Apportionment
• Chemometrics
• +5 more

Philip K. Hopke, Ph.D., serves as an Adjunct Professor in both the Department of Public Health Sciences and Department of Environmental Medicine at the University of Rochester School of Medicine and Dentistry. With a distinguished career spanning over five decades since earning his Ph.D. from Princeton University in 1969, Dr. Hopke has established himself as a global leader in environmental chemistry and air pollution research. Ph.D. in Chemistry, Princeton University (1969) M.A. in Chemistry, Princeton University (1967) B.S. in Chemistry, Trinity College (1965) Dr. Hopke's pioneering work focuses on particulate matter source apportionment , where he developed innovative methodologies like dispersion-normalized positive matrix factorization (DN-PMF). His research integrates chemometrics , atmospheric chemistry , and environmental epidemiology to address critical air quality challenges worldwide. Recent projects span China's megacities, Iran's water crisis, and New York State's vehicle emission regulations, with particular emphasis on health impacts of source-specific pollutants. Analysis of his 15 most recent publications reveals consistent focus on advanced source apportionment techniques , health outcomes linked to air pollution , and policy evaluation using sophisticated statistical modeling. His work increasingly incorporates machine learning approaches while maintaining rigorous chemical characterization of environmental samples. Scientific Recognition Fellow of both the Air and Waste Management Association (2021) and American Association for Aerosol Research Recipient of the Lifetime Achievement Award in Chemometrics (2014) Albert Nelson Marquis Lifetime Achievement Inductee (2018) Multiple international awards including the Fissan-Pui TSI International Aerosol Research Award (2018) Dr. Hopke maintains an exceptionally active research program with collaborators across six continents, evidenced by his 2025 publications from China, Iran, Kazakhstan, and the United States. His work bridges fundamental atmospheric science with practical public health applications, particularly in evaluating regulatory impacts on air quality and health outcomes.

Najib AyasView profile

Associate Professor

• Sleep Apnea
• Critical Care Medicine
• Public Health
• +5 more

Dr. Najib Ayas is an Associate Professor in the Division of Critical Care Medicine, Department of Medicine, Faculty of Medicine at the University of British Columbia. He graduated with distinction from the University of Alberta in 1992, completed Internal Medicine residency at the Mayo Clinic in 1996, and postgraduate training in Respiratory, Critical Care, and Sleep Medicine at Brigham and Women's Hospital/Harvard Medical School in 2000. He joined the Sleep Disorders Program at UBC in September 2002 and has maintained an active academic career since. Dr. Ayas received his undergraduate education at the University of Alberta (General Science, 1986-1988), followed by his MD (1988-1992). He completed a Rotating Internship at St Thomas Medical Center in Akron, Ohio (1992-1993), Internal Medicine Residency at Mayo Graduate School of Medicine in Rochester, MN (1993-1996), Pulmonary & Critical Care Fellowship at Harvard (1996-2000), and a Master of Public Health from Harvard School of Public Health (2000-2002). Dr. Ayas's primary research focus centers on the public health and safety consequences of sleep apnea and sleep deprivation. His work spans multiple domains including cardiovascular consequences of sleep disorders, epidemiology of obstructive sleep apnea, development of diagnostic tools, and cost-effectiveness of treatments. He has made significant contributions to understanding how sleep disorders affect occupational safety, cardiovascular health, and overall quality of life. His research often involves interdisciplinary collaborations across sleep medicine, critical care, public health, and epidemiology. Analysis of Dr. Ayas's recent publications reveals a strong focus on obstructive sleep apnea (OSA), particularly its cardiovascular consequences, diagnostic approaches, and treatment effectiveness. His work spans basic science investigating mechanisms like intermittent hypoxia effects on endothelial function, to clinical trials examining CPAP therapy, to large epidemiological studies on OSA prevalence and impact. A notable trend is his increasing focus on special populations including patients with spinal cord injuries, pregnant women, and those with comorbid conditions like COPD. His research maintains a strong translational emphasis, bridging laboratory findings to clinical applications. BC Lung Association Career Development Award (2002) New Investigator Salary Award, CIHR/BC Lung Association Award (2002-2007) Scholar Award, Michael Smith Foundation (2004-2009) Established Clinician Scholar Award, VCHRI (2009-2012) Award for Clinical Teaching Excellence, Division of Critical Care Medicine UBC (2013) Martin Hoffman Award Excellence in Research As an educator, Dr. Ayas has supervised numerous graduate students including Masters candidates, Doctoral students, and Post-doctoral fellows. His students have pursued research in areas including sleep apnea pathophysiology, cardiovascular consequences of sleep disorders, and clinical applications of sleep medicine. Dr. Ayas has served on multiple grant review panels for organizations including CIHR, Canadian Lung Association, and Michael Smith Foundation, contributing to the evaluation and funding of critical research in respiratory and sleep medicine. He has directed the Respiratory Physiology course (MED560/Path518) at UBC since 2006 and has been instrumental in developing clinical guidelines including the Canadian Thoracic Society and Canadian Sleep Society position paper on obstructive sleep apnea and driving.

James MillonigView profile

Associate Professor

• Neuroscience
• Developmental Biology
• Genetics
• +5 more

James Millonig is an Associate Professor in the Department of Neuroscience and Cell Biology at Rutgers University, where he also serves as the Senior Associate Dean for the Rutgers School of Graduate Studies. He is affiliated with the Center for Advanced Biotechnology and Medicine (CABM) and Robert Wood Johnson Medical School. His research focuses on understanding dorsal central nervous system (CNS) development, particularly through the integration of mouse genetics with neuroanatomy. His lab investigates how signaling centers like the roof plate coordinate CNS development through secreted factors such as Bone Morphogenetic Proteins (BMPs). A significant portion of his work examines the role of transcription factors like Lmx1a and Engrailed-2 in neural development and their potential connections to autism spectrum disorder (ASD). Dr. Millonig's recent publications demonstrate a continued focus on neurodevelopmental disorders, particularly autism spectrum disorder. His work spans from basic developmental neuroscience examining dorsal CNS formation to translational research using patient-derived neural progenitor cells. His laboratory has made significant contributions to understanding how genetic variations affect early brain development in ASD, with recent studies analyzing brain stem cells from ASD patients to identify irregularities in very early brain development. Autism Research Program (ARP) Idea Development Award from Department of Defense (2022) Standing appointment as a member of the National Institute of General Medical Sciences (NIGMS) Training and Workforce Development Subcommittee C (2020) Dr. Millonig has secured multiple federal grants, including an ongoing project titled "Investigation of Professional Coaching as an Intervention to Support the Success of URG Biomedical Ph.D. Students" (2023-2026) funded by the National Institute of General Medical Sciences. He has served as Principal Investigator for projects including "A Mouse Knock-In Model for ENGRAILED 2 Autism Susceptibility" funded by the National Institute of Mental Health and has been Co-Principal Investigator on the "IMSD at Rutgers - New Brunswick" project. The Millonig Lab maintains an active research program with several graduate students and research associates. Current lab members include Stuart Cattel (Graduate Student) and Arif S W Kusuma (Graduate Fellow), with Paul Matteson serving as Research Associate I. The lab has previously trained Marcos Ayala-Rivera, Tomas Kasza, and Monal Mehta, demonstrating a strong commitment to mentoring the next generation of scientists in neuroscience and developmental biology.

• Training Science
• Exercise Physiology
• Physical Fitness
• +3 more

Mahmut Esat Uzun serves as an Assistant Professor in the Department of Coaching Education at Karabük University's Hasan Doğan Faculty of Sports Sciences since 2023, specializing in Training Science and Exercise Physiology. His research examines physiological responses to diverse exercise interventions across multiple athletic populations. His academic background includes: Doctorate in Coach Education from Selçuk University (2019) Master's in Physical Education and Sports (Thesis) from Selçuk University (2017) Bachelor's in Sports Management from Selçuk University (2011) Uzun's research focuses on experimental analysis of exercise modalities including Zumba, Tabata, and sport-specific training protocols. His work investigates physiological adaptations in sedentary populations, elite wrestlers, football players, and adolescent athletes, with particular attention to hormonal responses, physical fitness components, and pandemic-era exercise constraints. Current projects explore warm-up optimization for football performance and neuromuscular adaptations in combat sports. His 8 journal articles (2020-2025) demonstrate evolving expertise from foundational studies on balance abilities and table tennis risk assessment toward contemporary research on warm-up protocols and pandemic exercise adaptations. Collaborative patterns reveal strong institutional ties with Karabük University colleagues, particularly in applied sports physiology research. No scientific awards or recognitions have been documented in available records. Uzun has no recorded thesis advisement and no public information regarding research grants. His publication record suggests independent research leadership with frequent co-authorship on experimental studies rather than large-scale funded projects. No specific laboratory facilities or dedicated research teams are mentioned in available documentation, though his work consistently involves collaborative research groups within Karabük University's sports science department.

• Walking
• Gait Analysis
• Systematic Reviews
• +5 more

Eva Swinnen is a researcher at the Vrije Universiteit Brussel within the Brubotics Rehabilitation Research Center, focusing on physiotherapy, human physiology, and anatomy. Her work bridges robotics and rehabilitation medicine. Key research areas: Walking (100%), Gait Analysis (86%), Systematic Reviews (59%), Orthotic Devices (51%) Recent Publications (2025): Explore AI applications in stroke rehabilitation, virtual twin technology, and electrotherapy effects on muscle recovery. Notable collaborations include projects with KU Leuven and Radboud University Medical Center. 2022 Kuka Innovation Award Finalist 2019 Phase I & II App Development Competition Winner Supervision: Guided master's theses on topics like Kinect™ system validation, volleyball spike biomechanics, and EMG patterning in motor tasks. Currently involved in EU-funded TARGET consortium initiatives for stroke management.

Katrin J SvenssonView profile

Associate Professor

• Metabolic Disorders
• Peptide Hormones
• Proteomics
• +5 more

Dr. Katrin J Svensson is an Associate Professor of Pathology at Stanford University and Affinity Group Leader at the Stanford Diabetes Research Center. She received her Ph.D. from Lund University (2012) and completed postdoctoral training at Harvard Medical School/Dana-Farber Cancer Institute (2017). Her research focuses on discovering circulating factors and peptide hormones that regulate metabolism through computational, proteomic, and physiological approaches. Key discoveries: Isthmin-1 (glucose/lipid homeostasis), BRINP2-related peptide (anti-obesity effects), ANGPTL3 (fructose metabolism) Academic Affiliations: Bio-X, Cardiovascular Institute, Wu Tsai Human Performance Alliance, MCHRI Faculty Fellow Research Highlights: Mapping tissue-specific peptide secretion to identify orphan ligands Characterizing receptors like GPR151 for glucose regulation Developing mitochondria-targeted therapies for cancer and metabolic diseases Investigating dietary sugar impacts on systemic metabolism Scientific Awards: Churg Research Award (2019) McCormick and Gabilan Award (2018) NIH K99/R00 Pathway to Independence Award (2016-2021) SRC International Postdoctoral Fellowship (2013-2016) Teaching & Mentorship: Leads Advanced Cell Biology courses (BIO 214/BIOC 224/MCP 221) and mentors graduate students/postdoctoral researchers in Biochemistry, Biophysics, and Cancer Biology programs.

• Cancer
• Liver Pathology
• Tumor Suppression
• +6 more

Professor Alain de Bruin (born 1968) is a distinguished academic at Utrecht University, serving as Professor in the Department of Biomolecular Health Sciences within the Faculty of Veterinary Medicine. Since January 1, 2020, he has been Head of the Department of Biomolecular Health Sciences. His academic journey began with veterinary medicine studies at the University of Hannover in Germany, followed by a PhD from the University of Bern in Switzerland in 1999. After specializing in veterinary pathology and completing a postdoctoral position at Ohio State University, he was appointed professor of pathobiology at Utrecht University in 2005. In 2010, he founded the Netherlands Molecular Pathology Center (UU/UMCG) and became an honorary professor of molecular pathology at the University of Groningen in 2014. Professor de Bruin's research primarily focuses on cancer biology, liver pathology, tumor suppression mechanisms, and aging processes. His expertise includes in vivo modeling, cell cycle analysis, generating transgenic mouse models, pathological analysis of animal disease models, and single-cell transcriptomics. His work centers on proteins that regulate cell proliferation, particularly E2F transcription factors, which he has discovered play critical roles in inhibiting cancer cell growth. His research themes span Life Sciences, Regenerative Medicine, and the Utrecht Platform for Organoid Technology. Analysis of his recent publications reveals a consistent research trajectory centered on cell cycle regulation, particularly the atypical E2F transcription factors (E2F7 and E2F8), and their roles in cancer development, polyploidization, and liver disease. His work demonstrates how these factors influence tumor suppression, angiogenesis, and cellular responses to DNA damage. The publications span multiple disciplines including cancer biology, molecular oncology, hepatology, and regenerative medicine, with applications in both human and veterinary medicine. Professor de Bruin has held significant leadership positions, including chairing the research council (2017-2019) and coordinating the 'Regenerative Medicine, Stem Cells, and Cancer' research program (2013-2019). He serves on the editorial board of 'Frontiers in Cell and Developmental Biology' and participates in review committees for NWO-Rubicon/Veni, the research alliance UTwente/UU/UMCU, and the Comprehensive Cancer Center at Ohio State University. His laboratory work has made significant contributions to understanding how E2F transcription factors regulate cell proliferation, with implications for developing novel cancer therapy strategies. His research on polyploidization mechanisms has provided insights into liver regeneration and tumor development, while his work on senescence has implications for aging-related diseases.

• Cardiovascular Epidemiology
• Sex and Gender Differences in Cardiovascular Disease
• Comparative Effectiveness Research
• +5 more

Louise Pilote, MD, MPH, PhD is Professor of Medicine in the Department of Medicine, Division of Internal Medicine , McGill University , and Senior Scientist in the Cardiovascular Health Across the Lifespan Program at the Research Institute of the McGill University Health Centre (RI-MUHC) , Montréal, Canada. Education: Louise Pilote holds the combined degrees of MD, MPH, and PhD, reflecting advanced clinical, public-health and research training that underpins her translational work. Research Focus: Internationally recognized pioneer in sex- and gender-based cardiovascular epidemiology , developing novel gender indices to disentangle biological (sex) and sociocultural (gender) determinants of cardiovascular outcomes. Leads the multinational GOING-FWD consortium (Gender Outcomes International Group to Further Well-being Development), integrating sex/gender analytics across 30 cohorts totaling 30 million patients with chronic diseases. Authority on comparative effectiveness and pharmacoepidemiology leveraging administrative “Big Data”, clinical registries, and advanced biostatistical/machine-learning methodologies. Current clinical-translational projects include imaging-based diagnosis of coronary microvascular dysfunction , a condition disproportionately affecting women. Scientific Impact & Awards: While formal awards are not enumerated in the supplied text, Dr Pilote’s sustained leadership as senior author on major Canadian and international cardiovascular guidelines, her role in founding the GOING-FWD network, and her extensive publication record (398 PubMed-indexed articles, 1988-2025) collectively constitute significant peer recognition. Students & Mentoring: Specific trainee names are not provided in the text; however, as Professor at McGill and Senior Scientist at RI-MUHC she supervises graduate students, clinical research fellows, and post-doctoral researchers in cardiovascular epidemiology, data science, and gender medicine. Laboratories & Teams: Dr Pilote heads the cardiovascular epidemiology research group within the Centre for Outcomes Research and Evaluation (CORE) at RI-MUHC, coordinating a multi-disciplinary team of biostatisticians, data scientists, clinician-scientists, and trainees.