Find Academic Supervisors

• Bioelectronic Medicine
• Synthetic Biology
• Nanotechnology
• +4 more

Ritchie Chen is an Assistant Professor at the University of California, San Francisco (UCSF) in the School of Medicine , specifically within the Department of Neurological Surgery. His research focuses on developing bioelectronic medicine technologies that integrate synthetic biology , nanotechnology , device engineering , and systems neuroscience to create genetically-targeted tools for mapping and modulating neural circuits with minimal tissue damage. Education: B.S. in Bioengineering and Materials Science and Engineering (University of California, Berkeley, 2010), Ph.D. in Materials Science and Engineering (Massachusetts Institute of Technology, 2016) Key Research Areas: Neural Circuit Engineering , Noninvasive Brain Stimulation , Transient Electronics for Medicine , and Genome Architecture in Neuroscience His recent publications demonstrate expertise in optogenetics , magnetic nanotechnology , and bioelectronic interfaces . Notable works include wireless magnetothermal deep brain stimulation (Science, 2015) and transient electronics for neural circuits (ACS Central Science, 2019). While no specific scientific awards are listed, his research has been widely discussed across academic platforms.

Philippe KrebsView profile

Professor

• Immunology
• Infectious Diseases
• Cancer Research
• +3 more

Prof. Dr. sc. nat. Philippe Krebs is a Group Leader at the Institute of Tissue Medicine and Pathology , affiliated with the University of Bern . His research focuses on immunology, cancer biology, and infectious diseases, particularly the role of innate immune cells in tumor microenvironments and inflammatory conditions. Key Research Areas: Innate lymphoid cells (ILC2), IL-33 signaling, tumor immunology (colorectal and prostate cancer), bone marrow interactomics, and organ-on-chip models. Recent Trends: Utilizing AI for immune cell quantification in cancer, developing lipid-based gels for ulcerative colitis, and engineering nanoparticles to mimic natural killer cell functions for leukemia therapy. Techniques: Single-cell transcriptomics, organ-on-chip systems, and molecular regulation studies of immune checkpoints.

Chinmay TrivediView profile

Professor

• Histone Deacetylases
• Cardiac Development
• Congenital Heart Disease
• +7 more

Dr. Chinmay Trivedi is a Professor of Medicine at UMass Chan Medical School , with additional affiliations in Molecular, Cell and Cancer Biology, and Translational Science programs. His research focuses on elucidating chromatin-modifying mechanisms in congenital cardiovascular and lymphatic diseases. Director, Division of Cardiovascular Medicine Research Research Director, Translational Science Program (Morningside Graduate School) Principal Investigator in Trivedi Lab Research Highlights: His laboratory established causal links between: Hdac3 mutations and Emberger syndrome (lymphedema) through non-coding DNA element analysis KRAS/BRAF mutations and hepatic vascular cavernomas with RAS-MAPK1 pathway inhibition as treatment Hdac1/Hdac2 roles in cryptic transcription suppression during cardiogenesis Tbx5-Hdac3 interactions in Holt-Oram syndrome pathogenesis YAP1 activation in vascular tumor epithelioid hemangioendothelioma Publication Trends show consistent work across Journal of Clinical Investigation , Science Advances , and Circulation Research , with recent emphasis on: Epigenetic regulation of cardiovascular development Signaling pathway modulation in lymphatic diseases Translational models for congenital defects Metabolic basis of cardiac pathologies Training Opportunities: The lab offers rotation projects for graduate students and postdoctoral positions requiring expertise in: Murine models ChIP-seq and epigenetic analysis Biochemical signaling assays Translational biology techniques Key Concepts: Histone deacetylases, non-coding DNA, RAS-MAPK1 pathway, oscillatory shear stress, cryptic transcription, enhanceosome complexes

Shannon RoseView profile

Associate Professor

• Autism Spectrum Disorders
• Pediatric Obesity
• Immunometabolism
• +5 more

Shannon Rose, PhD, is an Associate Professor in the Department of Health Promotion and Disease Prevention at the University of Tennessee Health Science Center (UTHSC) College of Nursing, Memphis, TN. She joined the faculty in July 2024 after serving as an Assistant Professor in Pediatrics at the University of Arkansas for Medical Sciences, bringing extensive expertise in pediatric immunometabolism and neurodevelopmental disorders. Her educational background includes: PhD in Interdisciplinary Biomedical Sciences (Cell Biology emphasis) from University of Arkansas for Medical Sciences BS in Biology from University of Central Arkansas Dr. Rose's research program centers on immune cell metabolism in children , investigating how bioenergetic alterations in circulating immune cells drive inflammation and metabolic decline in autism spectrum disorders (ASD) , obesity , insulin resistance , and type 2 diabetes . Her work integrates transcriptomics and metabolomics to discover diagnostic biomarkers, with current projects funded by The Brain Foundation focusing on autoantibody/cytokine profiles in ASD. Analysis of her 15 most recent publications (2022-2025) reveals dominant themes of mitochondrial dysfunction and bioenergetic signatures in pediatric populations, particularly using multi-omics approaches (mRNA/microRNA profiling, metabolomics) to identify blood-based biomarkers. Key discoveries link environmental factors like air pollution to neurodevelopmental regression in ASD and connect immune metabolism to metabolic disorders. No scientific awards, prizes, or medals were documented in the provided materials. Her research program is sustained by significant extramural funding: Current: The Brain Foundation grant for ASD biomarker discovery Completed: United States-Israel Binational Science Foundation grant for transcriptomics-based ASD diagnostics Past: National Institute of General Medical Sciences grant for pediatric obesity immunometabolism These projects have generated over 50 peer-reviewed publications and established collaborations across multiple institutions. Dr. Rose leads a research team within UTHSC's College of Nursing focused on pediatric immunometabolism, collaborating with Arkansas Children's Research Institute and international partners to advance understanding of metabolic-immune interactions in neurodevelopmental disorders.

• Metabolic Flux Analysis
• Stable Isotope Tracing
• Nuclear Magnetic Resonance (NMR)
• +10 more

Dr. Shawn C. Burgess is a researcher at the University of Texas Southwestern Medical Center (UTSW), affiliated with the Department of Pharmacology and the Center for Human Nutrition. His work focuses on metabolic flux regulation in diseases such as obesity, insulin resistance, and diabetes, utilizing stable isotope tracers, Nuclear Magnetic Resonance (NMR) spectroscopy, and mass spectrometry to investigate oxidative and biosynthetic metabolic pathways. Key research themes include mitochondrial metabolism, pyruvate cycling, and the role of metabolic mechanisms in pathologies like steatosis, oxidative stress, and inflammation. He has contributed to understanding how hepatic metabolic dysfunction contributes to hyperglycemia and fatty liver disease through advanced fluxomic analyses. Dr. Burgess has co-authored over 96 publications, with recent studies (2023–2024) exploring topics such as ketogenesis adaptation, acetyl-CoA oxidation, and pharmacological interventions targeting metabolic diseases. Earlier works (2001–2003) established foundational insights into isotopomer analysis for metabolic flux in liver and cardiac systems.

• Immunology
• Lymphatic System Biology
• Cancer Metastasis
• +4 more

David Jackson serves as Professor of Human Immunology and Principal Investigator of the Lymphatic Trafficking Research Group at the MRC Translational Immune Discovery Unit (MRC TIDU), part of the MRC Weatherall Institute of Molecular Medicine (WIMM) at the University of Oxford. He holds college affiliations with Harris Manchester College and Wolfson College, and maintains active research collaborations across Oxford, the UK, and internationally including institutions in Leeds, Zurich, and Cologne. His educational background includes a B.A. in Natural Sciences and Ph.D. in Biochemistry. Key research interests focus on: Molecular mechanisms of immune cell trafficking via lymphatic vessels Tumor metastasis through lymphatic systems Hyaluronan biology and LYVE-1 receptor function Lymphatic involvement in inflammation, immunity, and cancer Cardiac repair mechanisms post-myocardial infarction Analysis of recent publications reveals consistent focus on LYVE-1 receptor structural biology, leukocyte transmigration mechanics, and lymphatic metastasis pathways. His work integrates advanced techniques including super-resolution imaging, X-ray crystallography, and transgenic mouse models to investigate hyaluronan-mediated cell trafficking. Scientific recognition includes: Aselli Award Winner (2023) Professor Jackson actively mentors researchers, with notable lab alumni including Tess Stanly, Suneale Banerji, and Kayla Holder. His research is primarily funded by the Medical Research Council UK, with investigations spanning inflammatory bowel disease, transplant rejection mechanisms, and cardiac lymphatic remodeling. The Lymphatic Trafficking Research Group maintains strong international collaborations with leading scientists in biophysics, dermatology, and developmental biology.

• Genomics
• Personalized Medicine
• Translational Medicine
• +3 more

Jenny Taylor is a Professor at the University of Oxford , serving as Programme Director for the Genomic Medicine Theme within the Nuffield Department of Medicine and affiliated with the Wellcome Trust Centre for Human Genetics . Her work bridges genetics research with clinical applications through the Oxford Biomedical Research Centre , focusing on translational medicine and NHS integration. Focuses on genomics and personalized medicine Develops genomic technologies for clinical diagnostics Collaborates with Oxford University Hospitals Trust Integrates research into bedside clinical practice Her research emphasizes whole-genome sequencing , gene panels for cancer diagnostics, and non-coding variant interpretation . Projects span heart disease , leukaemia , cancer , and neurodegenerative conditions , with recent publications analyzing circulating tumor DNA, structural variants in developmental disorders, and computational drug design. Recent 15 articles (2022-2025) demonstrate expertise in genomic diagnostics for rare diseases, splice variant analysis , and non-coding mutation interpretation . Collaborative work in cancer genomics , neurodevelopmental disorders , and structural variation detection highlights translational impact.

• Mechanotransduction
• Cardiovascular Biology
• Endothelial Mechanosensing
• +5 more

Ellie Tzima is Professor of Cardiovascular Biology and Wellcome Trust Senior Fellow at the University of Oxford's Radcliffe Department of Medicine, leading the Tzima Mechanotransduction Group. Her pioneering research investigates how endothelial cells decode hemodynamic forces into biochemical signals governing vascular health and disease, with major implications for understanding atherosclerosis and heart failure. Her work centers on endothelial mechanosensing mechanisms, particularly how laminar versus disturbed blood flow patterns regulate inflammatory pathways and vascular remodeling. Key discoveries include identifying plexin D1 and JCAD as critical mechanotransducers, and elucidating novel endothelial-cardiomyocyte communication pathways essential for cardiac development. The laboratory employs multidisciplinary approaches spanning bioengineering, magnetic tweezers, molecular biology, and transgenic animal models to dissect force-sensing mechanisms at cellular and molecular levels. Analysis of her recent publications reveals strong thematic continuity in cardiovascular mechanobiology, with increasing focus on proteostasis regulation, ribosomal adaptation to mechanical stress, and endothelial-to-mesenchymal transition pathways. Her work demonstrates how mechanical forces directly modulate protein translation machinery and inflammatory responses, bridging biomechanics with molecular pathophysiology in vascular disease contexts. Wellcome Trust Senior Fellow Professor Tzima's research program integrates genetic mouse models, advanced imaging, RNA sequencing, and metabolomics to investigate intercellular communication in the heart and vascular system. Her laboratory maintains active collaborations with the Channon and Watkins labs on coronary artery disease genetics, with ongoing work focused on harnessing mechanotransduction pathways for novel anti-inflammatory therapeutics targeting cardiovascular disease.

• Cardiovascular Medicine
• Nitric Oxide Metabolism
• Vascular Remodeling
• +3 more

Dr Surawee Chuaiphichai is a Postdoctoral Research Fellow at the University of Oxford, affiliated with the Channon Group (Cardiovascular functional genomics and redox signaling) within the RDM Division of Cardiovascular Medicine. He earned a BSc (Hons) and DPhil through a British Heart Foundation studentship, focusing on endothelial cell Gch1 and BH4 biosynthesis in vascular health and disease. Education: BSc (Hons), DPhil Key Affiliation: Centre for Human Genetics, University of Oxford His research examines nitric oxide metabolism , vascular remodeling , and therapeutic interventions in cardiovascular disorders. Using endothelial cell-specific knockout models, he demonstrated BH4's role in hypertension and pregnancy complications, proposing 5-MTHF supplementation as a treatment strategy. His publications (2014–2023) explore BH4's mechanisms in gestational hypertension , ischemia-reperfusion injury , and angiogenesis , appearing in journals like Hypertension and American Journal of Physiology . Key themes include endothelial dysfunction , oxidative stress , and gene-environment interactions . Scientific Award: British Heart Foundation 4-year DPhil Studentship

Christopher ToepferView profile

Associate Professor

• Cardiovascular Science
• Cardiology
• Genetic Disorders
• +3 more

Christopher Toepfer is an Associate Professor of Cardiovascular Science at the University of Oxford , focusing on inherited and acquired heart diseases within the Medical & Health domain. His work bridges molecular mechanisms with therapeutic applications in cardiomyopathies. Research spans hypertrophic cardiomyopathy , sarcomere biology , and genetic disorder therapies Develops hiPSC-based models and automated analysis tools (CalTrack, SarcTrack) Investigates protein dysregulation , metabolic pathways , and CRISPR/Cas9 applications His recent publications highlight advancements in ALPK3 truncation therapies , titin enhancer function , and EGFR-mediated stromal activation in cardiomyopathies. He explores myosin dynamics , calcium signaling , and hypoxia-inducible factor roles using innovative imaging and genetic techniques. Current trends in his work include precision medicine approaches for sarcomere-related diseases, cross-species muscle physiology comparisons, and non-linear optical microscopy applications for cardiovascular diagnostics.

Barbara CianiView profile

Senior Lecturer

• Biophysical Chemistry
• Protein Self-Assembly
• Membrane Biology
• +3 more

Dr. Barbara Ciani is a Senior Lecturer in Biophysical Chemistry at the University of Sheffield's School of Mathematical and Physical Sciences. She serves as the Chemistry Biological Safety Officer and is affiliated with the RSC Biophysical Chemistry Interest Group and EPSRC review college. Research Interests: Protein self-assembly mechanisms, nuclear envelope repair, ESCRT-III complex dynamics, and protein solution physical chemistry. Teaching: Thermodynamics, Biophysical Chemistry, Toxicology, Bioinformatics, and Protein Design across undergraduate and postgraduate modules. Her lab combines biochemistry, cell biology, and protein design to address membrane repair signals and protein formulation optimization with industry partners. Recent publications focus on membrane remodeling, protein-stability relationships, and disease-associated protein interactions. Collaborations span academic and industrial domains, emphasizing biomimetic applications and drug discovery science.

Beth PruittView profile

Professor

• Mechanobiology
• Cell Biomechanics
• Microfabrication
• +7 more

Beth Pruitt is a Professor and Mehrabian Chancellor's Chair in the Department of Bioengineering at the University of California, Santa Barbara, with additional affiliations in Mechanical Engineering. She is a highly recognized researcher in the field of mechanobiology and microfabrication, holding fellowships in multiple prestigious societies including ASME, AIMBE, BMES, and AAAS. Dr. Pruitt's research lies at the intersection of mechanobiology, microfabrication, engineering and science, with her lab specializing in engineering microsystems and biointerfaces for quantitative mechanobiology. Her work focuses on understanding the role of mechanics in biology, force sensitive pathways in cell-to-cell adhesion, subcellular organization, and the mechanical environment's effect on stem cell derived cardiomyocytes as biophysical models of health and disease. She has developed custom microfabricated sensors and systems to answer fundamental questions in physiology, biology, stem cells, neuroscience and cardiology. Her research group has made significant contributions to mechanobiology through techniques like high-throughput single-cell assays, mechanobiology assays, microfabrication of cell culture devices, and biomaterials characterization. The lab has developed innovative tools including PiezoD software for sensor design optimization, microfluidic traps for C. elegans studies, and platforms for evaluating cardiomyocyte responses to mechanical stimuli. Dr. Pruitt has received numerous honors including the NSF CAREER Award, DARPA Young Faculty Award, and Denice Denton Leadership Award. Her lab is supported by extensive funding from NIH, NSF, AHA, and other major agencies. She has mentored numerous students and postdocs who have become co-authors on her extensive publication record spanning mechanobiology, cell adhesion, and cardiac mechanics. Her work bridges engineering and biology to address fundamental questions about how mechanical forces influence cellular behavior, with applications ranging from understanding basic biological processes to developing diagnostic tools and therapeutic approaches for cardiac diseases.

• Neuroscience
• Cardiovascular Medicine
• Hypertension
• +3 more

John Osborn is a Professor in the Department of Surgery at the Institute for Engineering in Medicine, University of Minnesota , with a focus on hypertension , renal medicine , and neurocardiology . His research explores autonomic regulation, neural stimulation, and interventional therapies for cardiovascular disorders. Current projects include vagus nerve stimulation for cardiovascular modulation (2021-2028), renal denervation trials with Ablative Solutions (2021-2026), and transcriptomic analysis of sensory neurons in neurogenic hypertension (2024-2025). His work contributes to UN Sustainable Development Goals through medical device innovation and precision hypertension treatment . Research Trends : Recent publications focus on renal nerve mechanisms , vagal excitation , and neurohumoral interactions in cardiovascular disorders, with interdisciplinary applications spanning neuroscience , physiology , and biomedical engineering . Collaborations : Dr. Osborn works with institutions like NIH , Verve Medical , and Augusta University , collaborating with experts in neurology , biomedical engineering , and cardiovascular medicine .

• Biochemistry
• Molecular Biology
• Biophysics
• +3 more

Joseph M Muretta is an Assistant Professor in the Department of Biochemistry, Molecular Biology, and Biophysics at the University of Minnesota and a key member of the Masonic Cancer Center. His research bridges structural biology, cancer signaling, and protein engineering, with a focus on therapeutic innovation. NIH-funded studies on Notch activation mechanisms for CAR T-cell immunotherapy Investigations into Aurora kinase A's allosteric scaffolding roles in oncology Structural analysis of dystrophin's actin-binding domains High-throughput screening methods using fluorescence resonance energy transfer Research Themes: Dr. Muretta's work spans structural biology and biophysics , particularly in understanding protein conformational changes and enzyme regulation. His projects often integrate cancer biology with biochemical engineering , developing tools like nanobodies and toxin-based systems for therapeutic applications. Recent collaborations highlight expertise in macrophage function within tumor microenvironments. Publication Trends: Over the past five years, publications reveal a trajectory from structural characterization of cytoskeletal proteins to allosteric signaling in oncogenic pathways, culminating in innovative immunotherapy platforms . Methodologies emphasize single-molecule fluorescence , crystallography , and high-throughput screening . Grants & Collaborations: Currently leading NIH-funded projects on Notch activation, while contributing to major collaborative grants including: NIH Cancer Center Support Grant (2024-2029) Sarepta Therapeutics partnership on dystrophin stability NIH grants exploring Aurora kinase targeting in cancer

• Cardiovascular Diseases
• Autophagy
• Molecular Mechanisms
• +5 more

Sebastiano Sciarretta is a Full Professor at the Department of Medical-Surgical Sciences and Biotechnologies at Sapienza University of Rome. His academic career spans both Italian and American institutions, including a tenure as Assistant Professor at Rutgers New Jersey Medical School. He holds a Medical Degree, Cardiology Specialty, and PhD in Experimental Medicine from Sapienza University of Rome. Dr. Sciarretta's research interests focus on cardiovascular diseases with particular emphasis on autophagy, oxidative stress, molecular mechanisms, cardiac regeneration, hypertension, and heart failure. His work bridges basic science with clinical applications, investigating cellular and molecular pathways that contribute to cardiovascular pathologies and potential therapeutic interventions. His recent publications highlight his ongoing investigation into autophagy mechanisms, natriuretic peptides, mitochondrial dysfunction, and the impact of environmental factors on cardiovascular health. These studies demonstrate a consistent focus on translational research that connects molecular discoveries with clinical applications. Young Investigator Award Research Competition (2009) Bristol-Meyers-Squibb Prize for Cardiovascular Prevention and Diabetes (2009) Melvin L. Marcus Young Investigator Award Finalist (2011) Best Moderated Poster at ESC Congress 2016 Platinum Award, Top Reviewers of the Year from Circulation Research (2017) Dr. Sciarretta has secured significant grant funding from multiple sources including the Italian Ministry of Research, Italian Ministry of Health, Leducq Foundation Transatlantic Network, New Jersey Commission on Cancer Research, and American Heart Association. His research group, "Autophagy and Cardiovascular Diseases," focuses on molecular mechanisms underlying cardiovascular pathologies with particular interest in doxorubicin-induced cardiomyopathy and atrial natriuretic peptide effects. He leads the research laboratory for Experimental Cardiovascular Pathology and maintains active editorial roles with several prestigious journals including Circulation Research and Autophagy, reflecting his standing in the cardiovascular research community.