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Edwin MooreView profile

Professor

• Cardiac Physiology
• Excitation-Contraction Coupling
• Calcium Signaling
• +3 more

Dr. Edwin Moore is Professor and Head of the Department of Cellular and Physiological Sciences at the University of British Columbia Faculty of Medicine. His research focuses on excitation-contraction coupling mechanisms in cardiac and smooth muscle cells. B.Sc. and M.Sc. in Physiology from the University of Toronto Ph.D. in Pharmacology from the Mayo Clinic Research Interests: Dr. Moore's laboratory investigates the type-2 cardiac ryanodine receptor (RyR2) that regulate cardiac contractile force through calcium release dynamics. His team examines RyR2 position/function in normal and diseased tissue using: Transmission electron microscopy Electron tomography 3D superresolution immunofluorescence Transgenic mouse models Ca 2+ spark/transient analyses Biochemical approaches Scientific Collaborations: The lab collaborates with Dr. Keng Chou (Chemistry Dept.) for dSTORM system development and is part of UBC's Cardiovascular Research Group . Current projects include: Investigating RyR2 variants' pathogenicity using iPSC-derived cardiomyocytes Studying dynamic RyR2 interactions through post-translational modifications Developing novel correlative microscopy techniques Lab Members: The interdisciplinary team includes Dr. Parisa Asghari (Research Associate), Dr. David Scriven (Research Associate), and Saif Dababneh (MD/PhD student).

Kelly DrewView profile

Professor

• Hibernation Biology
• Neuroprotection
• Adenosine Receptor Agonists
• +5 more

Kelly Drew is a Professor in the Department of Chemistry and Biochemistry at the University of Alaska Fairbanks. She directs the NIH-funded Center for Transformative Research in Metabolism, a Center of Excellence in Hibernation Science, focusing on neuroprotective mechanisms in hibernators and their translation to neurocritical care. Her work bridges biochemistry, neuroscience, and physiology. B.S., Psychology (1981), University of Alaska Fairbanks Ph.D., Pharmacology (1987), Albany Medical College Post-doctoral Fellow, Pharmacology, Karolinska Institute (1987-1990) Research interests center on: Intrinsic neuroprotective properties of Arctic ground squirrel brains Synaptic remodeling during hibernation torpor and arousal Central nervous system regulation of metabolic suppression Therapeutic hypothermia applications Ischemia tolerance mechanisms Her publications highlight translational potential from hibernation biology to human critical care, particularly through adenosine receptor agonists. Scientific awards include the Dennis Demmert Award (2005), Usebelli Teaching Award (2006), and Sven O.E. Ebbesson Neuroscience Award (2006). Contact: kdrew@alaska.edu | Phone: 907-474-7190 | Address: Murie Building, Rm 223F, University of Alaska Fairbanks.

• Biomedical Engineering
• Respiratory Physiology
• Critical Care Medicine
• +5 more

Andrew Farmery is a Professor of Anaesthetics at the University of Oxford , where he serves as Head of the Nuffield Division of Anaesthetics . He is also a Fellow & Tutor in Medicine at Wadham College , Oxford, overseeing undergraduate medical education. Research Interests : His work bridges biomedical engineering and respiratory physiology , focusing on developing intravascular sensors and analytical techniques to monitor respiratory and cardiovascular dysfunction in critically ill patients. Key projects include the Inspired Sinewave Technique (IST) , which quantifies lung heterogeneity , cardiac output , and ‘baby lung’ volume in ARDS and COPD models. He emphasizes translating these innovations into medical devices for improved patient care, supported by grants from the Wellcome Trust , EPSRC , and NIHR . Publications : His recent articles highlight the IST as a non-invasive tool for assessing lung injury , ventilation heterogeneity , and hemodynamic changes in animal models . Studies span ARDS , COPD , and PPE sustainability , reflecting interdisciplinary applications. Methodological works include computational simulations and CT validation for physiological modeling. Labs & Teams : He leads the Respiratory Physiology and Biomedical Engineering Group and is affiliated with the Ventilator Weaning and Extubation in Neurocritical Care Network , integrating clinical and engineering expertise.

• Stroke
• Vascular Neurology
• Neuroimaging
• +3 more

Joseph Schindler, MD is a Professor of Neurology & Neurosurgery at Yale University School of Medicine. He serves as the Clinical Chief of the Division of Vascular Neurology, Director of the Yale New Haven Comprehensive Stroke Center, and Director of the Yale New Haven Telestroke Service. His clinical work focuses on acute stroke management, vascular neurology, and implementing innovative stroke care delivery systems across healthcare settings. Dr. Schindler completed his medical degree at Tufts University School of Medicine in 2001 and earned his BA from Tufts University in 1994. He completed his residency at Yale University School of Medicine between 2002-2005. His research interests center on ischemic stroke, neuroimaging, and stroke care systems with particular emphasis on health disparities, portable MRI technology for stroke evaluation, and optimizing stroke treatment pathways. His work examines how socioeconomic factors impact stroke outcomes and treatment delays, the application of novel imaging technologies at the bedside, and the intersection of stroke with other medical conditions including cardiovascular disease and infectious diseases like COVID-19. He has published extensively on topics ranging from TIA management protocols to neurological complications of viral infections. Analysis of Dr. Schindler's recent publications reveals a strong focus on translational stroke research with practical clinical applications. His work spans multiple domains including health services research examining care delivery models, technological innovation in neuroimaging, and investigation of health disparities in stroke outcomes. A significant portion of his recent work addresses the impact of social determinants of health on stroke care, reflecting growing recognition of these factors in neurological outcomes. Dr. Schindler has received recognition as a Connecticut Magazine Top Doc in both 2015 and 2016, highlighting his clinical excellence and contributions to patient care in the region. He actively collaborates with numerous researchers across Yale and beyond, with frequent co-authorship with colleagues including Lauren Sansing, Charles Wira, Kevin Sheth, Guido Falcone, and Nils Petersen. His research is supported through various clinical trials including studies on anticoagulation therapies, blood pressure management during stroke recovery, and innovative stroke detection technologies. As Clinical Chief of Vascular Neurology and Director of the Comprehensive Stroke Center, Dr. Schindler leads multidisciplinary teams focused on acute stroke intervention, prevention strategies, and quality improvement initiatives aimed at optimizing stroke care across the continuum from pre-hospital settings through rehabilitation.

Eigil SamsetView profile

Professor

• Digital Signal Processing
• Image Analysis
• Medical Imaging
• +12 more

Eigil Samset is a Professor II in the Department of Informatics at the University of Oslo, affiliated with the Faculty of Mathematics and Natural Sciences. He is a key member of the Digital Signal Processing and Image Analysis (DSB) research group and contributes to the Strategic Research Initiative MEDIMA (Multimodal Medical Imaging and Image Analysis). His work is also associated with the INIUS (Intelligent Image-Guided Surgery) project, reflecting his strong focus on translational research in medical imaging. His research interests span artificial intelligence, deep learning, medical image analysis, echocardiography, and image-guided surgery . He specializes in developing advanced computational methods for cardiac ultrasound, including automated segmentation, motion tracking, and 3D/4D reconstruction. His work bridges computer science and clinical cardiology, aiming to improve diagnostic accuracy and procedural guidance. The recent publications show a consistent trend in applying deep learning to automate measurements in echocardiography, such as left ventricular strain, outflow tract diameter, and chamber segmentation. There is also a strong emphasis on biomechanical modeling, image fusion (e.g., ultrasound with fluoroscopy or CT), and real-time visualization for surgical applications. His work frequently appears in high-impact journals in medical imaging and biomedical engineering. He has advised or collaborated closely with numerous researchers and students, as evidenced by his frequent senior authorship on publications involving PhD candidates and postdocs. His research is supported by institutional affiliations and collaborative projects rather than individual grant mentions in the provided text. He is actively contributing to the field, with recent work in 2024, and maintains an academic email at the University of Oslo. There is no indication of retirement or emeritus status.

• Bio-integrated Electronics
• Flexible and Stretchable Electronics
• Optofluidics
• +7 more

Professor John A Rogers is a leading academic in materials science and biomedical engineering, currently holding the Louis Simpson and Kimberly Querrey Professor position at Northwestern University . He is also the founding Director of the Querrey-Simpson Institute of Bioelectronics , with joint appointments in Biomedical Engineering, Mechanical Engineering, Electrical Engineering, Chemistry, and Neurological Surgery. His research spans bio-integrated electronics, flexible devices, and nanofabrication technologies. Education : BA/BS in Chemistry and Physics (University of Texas, 1989); SM in Physics and Chemistry (MIT, 1992); PhD in Physical Chemistry (MIT, 1995). Rogers’ work focuses on Soft, skin-like electronics for vital signs monitoring, Bioresorbable devices for cardiac and neural applications, Injectable optoelectronics in neuroscience, and 3D microsystems for biomedical research. His team pioneers stretchable silicon , transient electronics , and bio-inspired fabrication methods. Recent research trends include millimeter-scale pacemakers , wireless skin-interfaced systems , and closed-loop bio-optoelectronics . These innovations leverage flexible substrates , nanoscale thermocapillary flows , and soft lithography for unprecedented biocompatibility and functionality. Scientific Awards : Sigma Xi William Procter Prize (2023), IEEE Biomedical Engineering Award (2023), James Prize (2022), Guggenheim Fellowship (2021), MacArthur Fellowship (2009), and multiple academy fellowships. Rogers leads a multidisciplinary team and has co-authored over 1000 peer-reviewed papers, with more than 100 patented technologies commercialized through startups. His lab’s 3D electronic pericardium and skin-integrated microfluidics exemplify his commitment to translating fundamental science into clinical solutions.

Peter Rugg-GunnView profile

Researcher

• Epigenetics
• Stem Cell Biology
• Human Developmental Biology
• +3 more

Dr. Peter Rugg-Gunn is a Group Leader at the Cambridge Stem Cell Institute and Head of Public Engagement at the Babraham Institute . His research focuses on the epigenetic regulation of pluripotency and early human development , investigating how chromatin organization, transcription factors, and non-coding RNA interact to shape cellular identity. Key areas include stem cell-based embryo models , heterochromatin dynamics , and age-related epigenetic changes in neural progenitors. Research Themes : Epigenetic programming in human embryogenesis, stem cell differentiation, and regenerative medicine applications Techniques : Single-cell multi-omics, promoter interactome mapping, chemical reprogramming protocols His work has influenced ISSCR guidelines for stem cell-based embryo models and revealed species-specific differences in X chromosome inactivation mechanisms. Current projects explore chromatin-based lineage barriers and epigenetic stability in human pluripotent stem cells.

Steven BalletView profile

Researcher

• Peptide Chemistry
• Medicinal Chemistry
• Molecular Pharmacology
• +3 more

Steven Ballet is a researcher at the Department of Chemistry, Vrije Universiteit Brussel (VUB), with a focus on peptide chemistry and medicinal applications. His work bridges chemical synthesis with biomedical translation, particularly in pain management and drug delivery systems. Research areas include: Peptide and peptidomimetic design GPCR-targeted ligands for opioid reduction Injectable hydrogels for controlled molecule release Nanobody-based molecular chaperones Recent publications highlight collaborations with bioreactor engineering teams and structural biology groups, advancing therapies for neurodegenerative and cardiac conditions. Projects like [ORACLE] and NAIROBI demonstrate translational impact. Scientific awards include: 2017 - 1st place ie-net-price for Bioengineers 2018 - 35EPS Bursary 2014 & 2017 - Chemistry excellence awards (KVCV) He supervises PhD students in molecular pharmacology and leads fundamental/applied projects involving bioreactors, NMR technology, and supramolecular assemblies.

Emily WongView profile

Associate Professor

• Bioinformatics
• Computational Genomics
• Regulatory Evolution
• +4 more

Associate Professor Emily Wong is a computational genomics researcher at the University of New South Wales (UNSW) and the Victor Chang Cardiac Research Institute. She holds a PhD and MSc in Bioinformatics and Computational Genomics from the University of Sydney and a BSc from UNSW. Her work focuses on integrating big data with in vivo experiments to decipher genetic and molecular mechanisms underlying cell diversity and disease regulation. Education: PhD (Bioinformatics & Computational Genomics), University of Sydney MSc (Bioinformatics & Computational Genomics), University of Sydney BSc, UNSW Research Focus: Regulatory evolution across mammalian tissues Enhancer conservation and function in development Epigenomic reprogramming in disease Iron homeostasis in aging and cancer Cis-regulatory syntax in transcriptional precision Her recent publications highlight cross-disciplinary approaches to understanding enhancer emergence, aging-related stem cell dynamics, and epigenetic therapy in breast cancer. She has received prestigious fellowships including an EMBO Postdoctoral Fellowship and an Australian Research Council Discovery Early Career Fellowship.

Lars MandrupView profile

Associate Professor

• Biomedical Engineering
• Signal Processing
• Machine Learning
• +5 more

Lars Mandrup is an Associate Professor in the Department of Electrical and Computer Engineering at Aarhus University, specializing in Signal Processing and Machine Learning. He serves as the Unions Representative for DM and is a member of LSU and LAMU. His primary responsibilities include educating Diploma and Master Engineers in Biomedical Engineering. Mandrup's research expertise lies in Physics, Mathematics, and Biophysics, with a strong focus on Biomedical Engineering. He applies Computational Fluid Dynamics (CFD) to Magnetic Resonance data for cardiovascular modeling, including blood flow analysis and mitral valve mechanics. Additionally, he is a key contributor to Electromagnetic Compatibility (EMC) research, developing foundational educational materials and advancing EMC testing standards and methods. His publication record shows a clear interdisciplinary trajectory, merging engineering with medical applications. Key themes include CFD-based cardiovascular simulations and EMC education. The biomedical work leverages MRI data to model complex physiological processes, while the EMC contributions span theoretical principles to practical testing standards, reflecting a commitment to both academic and industrial relevance. No scientific awards were mentioned in the provided information. Mandrup actively mentors students in Biomedical Engineering programs and serves as a PhD examiner. He is a member of the EMC group within the TUR Network for Electronics and Information Technology, which drives curriculum development in EMC education across Danish engineering institutions. He is affiliated with the EMC group (EMC-gruppen), dedicated to advancing EMC education and professional development. This group collaborates within the TUR Network to enhance teaching materials and methodologies for EMC courses.

Samira AzarinView profile

Associate Professor

• Cancer Immunotherapy
• Biomanufacturing of Immune Cells
• Blood-Brain Barrier Modeling
• +5 more

Samira Azarin is an Associate Professor and Director of Undergraduate Studies in the Department of Chemical Engineering and Materials Science at the University of Minnesota's College of Science and Engineering. Her research integrates biomaterials, cellular engineering, and stem cell biology to address critical challenges in cancer treatment and neurological disorders. Her primary research focuses include: Mechanisms of tumor progression and metastatic cancer treatment Biomanufacturing of natural killer (NK) cells for allogeneic cancer immunotherapy Stem cell-derived models of blood-brain barrier and intestinal epithelial barriers Cellular dormancy mechanisms and therapeutic applications Biomaterial scaffolds for in vivo cancer cell capture Recent publications (2021-2025) demonstrate strong trends in cancer immunotherapy, with particular emphasis on NK cell biomanufacturing and electroporation-based in-situ vaccination strategies. Her work increasingly incorporates advanced biomaterial platforms for physiological barrier modeling and metastasis prevention, reflecting a translational focus on moving from fundamental mechanisms to therapeutic applications. Scientific recognition includes: Editor's Choice article in Biotechnology and Bioengineering (2020) Editor's Choice article in Biotechnology and Bioengineering (2016) Editor's Award for Biology in International Journal of Hyperthermia (2019) Dr. Azarin has successfully mentored 23 graduate students to completion (2019-2024), with alumni placements at major pharmaceutical companies including Merck, AbbVie, Bristol Myers Squibb, Amgen, and 3M. Her lab emphasizes collaborative, equitable, and inclusive scientific development, with research supported by significant NIH and industry funding for NK cell biomanufacturing, metastasis modeling, and blood-brain barrier restoration. The Azarin Research Group maintains an active collaborative environment focused on quantitative biological analysis combined with tissue engineering approaches, regularly participating in events like the Cellular Bioprocess Technology short course and maintaining strong industry partnerships for therapeutic translation.

• Cardiac excitation/contraction coupling
• Calcium-induced calcium release
• Calcium channel selectivity
• +5 more

Dirk Gillespie serves as The John H. and Margaret V. Krehbiel Professor of Cardiology in the Department of Physiology & Biophysics at Rush Medical College, Rush University. His distinguished career bridges biophysics, cardiology, and theoretical chemistry, with a primary focus on calcium signaling mechanisms in cardiac muscle and nanofluidic systems. Dr. Gillespie's educational background includes: PhD in Physiology & Biophysics from Rush University MS from Northwestern University BA from Johns Hopkins University His research expertise centers on cardiac excitation/contraction coupling , calcium-induced calcium release , calcium channel selectivity , nanofluidics , and classical density functional theory of electrolytes . Through sophisticated mathematical modeling and computational approaches, Dr. Gillespie has made significant contributions to understanding ion channel function, particularly ryanodine receptors that mediate calcium release in cardiac cells. His work provides critical insights into the molecular mechanisms underlying cardiac arrhythmias and potential therapeutic approaches. Analysis of Dr. Gillespie's publication record reveals a consistent research trajectory from fundamental biophysical principles of ion channels toward increasingly sophisticated computational models that integrate multiple physical phenomena. His recent work demonstrates a strategic expansion from cardiac calcium signaling into nanofluidic systems and theoretical electrochemistry, while maintaining the core focus on ion transport phenomena. The publications show a strong emphasis on applying density functional theory to both biological systems and synthetic nanopores, highlighting the interdisciplinary nature of his research program. Dr. Gillespie directs an active research laboratory at Rush University focused on the biophysics of calcium signaling. His laboratory employs a combination of computational modeling, theoretical approaches, and collaborative experimental work to advance understanding of cardiac electrophysiology. The research program has been consistently supported by multiple grants from the National Institutes of Health and other scientific funding agencies, reflecting the significance and impact of his work in the field.

• Cardiovascular Medicine
• Obesity and Cardiometabolic Syndromes
• Myocardial Metabolism
• +4 more

Oliver Rider is a Professor of Cardiovascular Medicine at the University of Oxford and a British Heart Foundation Senior Clinical Research Fellow. He serves as Deputy Clinical Director of the Oxford Centre for Clinical Magnetic Resonance Research (OCMR) and as an Honorary Consultant Cardiologist. His research focuses on the interplay between myocardial metabolism, cardiac energetics, and function in diseases like heart failure, obesity, and diabetes. Education: BA (hons), BMBCh (hons), DPhil (Oxon) Professional Affiliations: Pembroke College, OCMR, Neubauer Group, Rider Group Key Research Themes: Cardiometabolic syndromes, obesity-related heart disease, hyperpolarized MRI techniques Rider's work spans clinical and translational research, utilizing advanced CMR imaging and spectroscopy to explore metabolic flexibility, myocardial energetics, and novel therapies like bariatric surgery and cardiac mitotropes. His group has pioneered studies on hyperpolarized [1-13C]pyruvate MRI and the role of cardiac metabolism in heart failure progression. Rider has received prestigious awards including the American Heart Association Young Investigator Award (2008), BHF/BCS Michael Davies Early Career Award (2019), and consecutive BHF Clinical Research Fellowships (2016-2022, 2022-present). His current research includes the AMEND Preserved trial, testing low-energy diets for HFpEF patients.

Tormod Skogstad NilsenView profile

Associate Professor

• Exercise Oncology
• Strength Training
• Muscle Physiology
• +2 more

Tormod Skogstad Nilsen serves as an Associate Professor at the Institute of Physical Performance at the Norwegian School of Sport Sciences. He holds both a master's degree and PhD from the same institution and is actively engaged in research on exercise interventions for cancer patients and survivors. His work bridges sports science and oncology, with a particular focus on understanding how physical activity can mitigate treatment side effects and improve quality of life. Dr. Nilsen's research interests center on exercise oncology, with special emphasis on strength training adaptations and muscle physiology in cancer contexts. His work spans multiple cancer types including prostate cancer (particularly examining effects of androgen deprivation therapy), breast cancer survivors, and patients undergoing various cancer treatments. He investigates how exercise impacts cardiovascular health, muscle function, and overall quality of life during and after cancer treatment. Analysis of his recent publication record reveals a strong focus on cardiorespiratory fitness outcomes in cancer survivors, with particular attention to breast cancer populations. His research employs diverse methodologies including randomized controlled trials, systematic reviews, and novel approaches to exercise dose reporting. A significant portion of his work examines the intersection of exercise physiology and cardiovascular health in cancer contexts, reflecting the growing field of cardio-oncology. As an educator, Dr. Nilsen serves as course leader for 'Exercise and Cancer' (THP303), a course developed in collaboration with Oslo University Hospital that provides certification as an AKTIV instructor through the Aktiv mot kreft foundation. He lectures extensively on exercise interventions for cancer patients and leads research studies investigating the effects of exercise on various side effects and late effects of cancer treatment. Dr. Nilsen is actively involved with the Norwegian Exercise Oncology Network (NEON) and collaborates extensively with Oslo University Hospital. His research program includes multiple clinical trials examining exercise interventions across different cancer types and treatment phases, with a particular emphasis on translating research findings into practical clinical applications for cancer rehabilitation.

Andrew RollinsView profile

Professor

• Biomedical optics
• Optical imaging
• Optical coherence tomography
• +5 more

Andrew Rollins is the Leonard Case Jr. Professor of Engineering in the Department of Biomedical Engineering at Case Western Reserve University's Case School of Engineering. He also holds an affiliation with the School of Medicine as a Member of the Cancer Imaging Program at the Case Comprehensive Cancer Center. His research focuses on developing advanced biomedical optical technologies, particularly optical coherence tomography (OCT), with applications in developmental cardiology, cardiovascular disease, and cancer imaging. Dr. Rollins earned his PhD in Biomedical Engineering from Case Western Reserve University and a BS in Electrical Engineering from Brigham Young University. His research interests span biomedical optics, optical imaging, optical coherence tomography, image analysis, cancer imaging, and cardiac imaging. His laboratory develops OCT technologies for studying developmental cardiology and endoscopic imaging of cardiovascular disease and cancer, including applications in optical stimulation and imaging of electrophysiology. His recent publications demonstrate strong trends in applying OCT to cardiac electrophysiology, embryonic heart development, and cancer imaging. The research consistently bridges engineering innovation with clinical applications, particularly in real-time guidance of cardiac procedures and non-invasive assessment of tissue properties. His work frequently involves interdisciplinary collaboration across engineering, medicine, and basic science disciplines. Fellow, American Institute for Medical & Biological Engineering (AIMBE) Fellow, SPIE International Leader Award 2020 Center for International Affairs International Activities Award 2014 CWRU School of Engineering International Activities Award 2011 Dr. Rollins serves as faculty advisor for CWRU SPIE and CWRU Engineers Without Borders, reflecting his commitment to student development and international engagement. His research has been supported by numerous grants enabling the development of novel optical imaging technologies. His laboratory focuses on translating OCT innovations from bench to bedside, with particular emphasis on cardiac applications and developmental biology models. Current projects include optical pacing of embryonic hearts, real-time guidance of cardiac ablation procedures, and non-invasive assessment of corneal crosslinking.