Cancer evolution Professors and Supervisors | ApplySharif

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Christina Louise LindhardtView profile

Associate Professor

University of Southern DenmarkDenmark

Christina Louise Lindhardt is an Associate Professor at the Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, and holds an Honorary Associate Professor position at Deakin University since 2023. Her work focuses on patient communication, medical education, and healthcare quality improvement. Active in cross-cultural adaptation studies for patient communication tools Develops innovative digital solutions for clinical training Researches motivational interviewing and compassion-based interventions Recent publications examine video consultation implementation in gynecological care, communication curriculum development for medical students, and specialized nursing roles in cancer care. She works extensively with qualitative methodologies and systematic reviews. Her projects include EU-funded initiatives like Changing Cancer Care and studies on technology integration in clinical practice. She has contributed to over 93 research outputs and participated in 50 activities since 2011.

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Rene JackstadtView profile

Researcher

German Cancer Research CenterGermany

Rene Jackstadt is a Junior Research Group Leader at the Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM) . His research focuses on cancer progression and metastasis , particularly in colorectal cancer , with a strong emphasis on stem cell biology , Wnt signaling , and epithelial-mesenchymal transition . He leads the Cancer Progression and Metastasis research group within the Normal and Malignant Stem Cells program. Position: HI-STEM Junior Research Group Leader Location: Im Neuenheimer Feld 280, Heidelberg, Germany Contact: r.jackstadt@hi-stem.de His work involves advanced organoid modeling and genetic manipulation to study tumor evolution and therapeutic vulnerabilities. Current projects explore: Stromal interactions in metastasis Immune checkpoint regulation Tumor microenvironment dynamics Signal transduction in oncogenesis Publications highlight his contributions to understanding: Wnt pathway in cancer MicroRNA regulation of MYC Stress-induced stem cell activation Tumor-immune co-evolution His team includes: PhD Students: Luisa Nader, Manuel Mastel, Gabriele Diamante, Nikolaos Georgakopoulos, Aitana Guiseris Martinez Research Assistant: Raja Flüchter

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AZIZ AzizView profile

Professor

University of Reims Champagne-ArdenneFrance

AZIZ Aziz is a Full Professor at the University of Reims Champagne-Ardenne since 2020, affiliated with the Faculty of Exact and Natural Sciences. He leads the research team Immunity and Beneficial Microorganisms (USC INRAE 1488) and has been instrumental in advancing plant disease resistance mechanisms through microbial interactions since 2012. PhD in Plant Biology (Rennes 1, 1996) Accreditation to supervise research (HDR, Reims 2003) Research Focus: AZIZ's work integrates physiological and molecular approaches to study plant stress responses, particularly grapevine's interaction with beneficial bacteria and MAMPs for induced resistance against pathogens like Botrytis cinerea and Neofusicoccum parvum . His team investigates polyamine-phytoalexin crosstalk, biocontrol agents , and sustainable viticulture solutions under climate change pressures. Publications (2015-2021) reveal consistent contributions to grapevine immunity , with emphasis on Bacillus subtilis and Pseudomonas fluorescens mechanisms, stilbene bioproduction , and stress-induced defense networks. Collaborations span IOBC , H2020-PRIMA , and ANR programs. Scientific Excellence Award (Ministry of Education) Review service for 12+ journals including New Phytologist and Molecular Plant-Microbe Interactions Teaching Leadership includes directing the Master's specialization Plant Production and Bioprotection (2015-2023) and designing curricula on phytoremediation , plant pathology , and ecophysiology . He has supervised 10 PhD graduates and mentored 50+ trainees.

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Alessandro Dal Palu'View profile

Associate Professor

University of ParmaItaly

Alessandro Dal Palu' is an Associate Professor at the Department of Mathematical, Physical, and Computer Sciences at University of Parma. He holds a PhD in Computer Science from University of Udine and has been with University of Parma since 2005, transitioning from Researcher to Associate Professor in 2014. His teaching portfolio includes courses on Computer Architecture, Constraint Programming, and Algorithms & Data Structures. His research spans computational logic, bioinformatics, and GPU computing. Notable achievements include the 2007 GULP award for his Ph.D. thesis and the ICLP 2010 best paper award. He has led Italian INdAM-GNCS research projects on GPU applications (2011) and Logic Programming in cancer genomics (2016). Recent publications focus on explainable AI frameworks, bioinformatics applications, and sustainable logistics solutions. His work integrates Answer Set Programming with biomedical challenges like protein structure analysis and cancer genome evolution. He chairs the International Conference on Logic Programming (ICLP 2018) and has organized multiple international workshops on constraint programming. 2007 GULP Award ICLP 2010 Best Paper PI for INdAM-GNCS projects (2011, 2016) Program Committee member for international conferences

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Cody S. CarterView profile

Assistant Professor

Loma Linda UniversityUnited States

Cody S. Carter, MD is an Assistant Professor in the Pathology and Human Anatomy Department, Pathology Division at Loma Linda University School of Medicine. He also serves as Assistant Dean for Basic Science Education within the School of Medicine. Dr. Carter is board certified by the American Board of Pathology in both Anatomic Pathology and Clinical Pathology. Dr. Carter's research focuses on surgical pathology with particular expertise in soft tissue tumors, breast pathology, and molecular diagnostics. His work encompasses diagnostic challenges in mesenchymal neoplasms, tumor classification, and the application of immunohistochemistry in diagnostic pathology. He has made significant contributions to understanding rare tumors including ossifying fibromyxoid tumors, biphenotypic sinonasal sarcoma, and various soft tissue lesions. His publication record spans from 2010 to 2023, demonstrating consistent scholarly activity in high-impact pathology journals. His research shows a clear trajectory from early work in neurosurgical complications and facial aging to his current focus on molecular pathology and tumor classification. Dr. Carter frequently collaborates with colleagues at Loma Linda University and other institutions, particularly in the areas of soft tissue tumors and breast pathology. Diplomate, American Board of Pathology Board Certification in Anatomic Pathology and Clinical Pathology Graduate, Leadership Institute (ASCP) Graduate, Laboratory Management University (ASCP) Graduate, Healthcare Administration Scholars Program (University of Michigan) As Assistant Dean for Basic Science Education, Dr. Carter plays a significant role in medical education, particularly in hematology and immunology instruction as evidenced by his teaching schedule. His professional development includes extensive participation in medical education conferences through the International Association of Medical Science Educators (IAMSE) and pathology leadership forums.

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Kristian AlmstrupView profile

Associate Professor

University of CopenhagenDenmark

Kristian Almstrup serves as Associate Professor at the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, and holds a Senior Scientist position at the Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet. His dual appointment bridges clinical practice and academic research in reproductive genetics. Dr. Almstrup's research primarily focuses on the intersection of genetic and epigenetic variation with reproductive endpoints, testicular gene expression, and sperm cell function. His work has pioneered understanding of piRNAs in human spermatogenesis, genetic variants causing non-obstructive azoospermia, and genetic factors associated with testicular germ cell cancer. His group employs cutting-edge techniques including single-cell/nuclei methods and spatial transcriptomics to study the complex cellular composition of testicular tissue. Analysis of Almstrup's 15 most recent publications reveals a consistent focus on male reproductive genetics, with particular emphasis on non-coding RNAs (especially piRNAs), genetic determinants of spermatogenic failure, and environmental factors in declining fertility. His research spans from basic molecular mechanisms to clinical applications, with several publications in high-impact journals including Nature, Nature Communications, and the New England Journal of Medicine. Dr. Almstrup actively contributes to medical education through teaching in the Medical Genetics course for Medicine and Molecular Biomedicine students, as well as organizing PhD courses in Genetics of Reproduction. His editorial work includes serving as Editor for Andrology, Scientific Reports, and Frontiers in Cell and Developmental Biology. The Almstrup Group, based at Rigshospitalet, maintains an active research program with current team members including Nina Mørup Nygaard, Sofia B. Winge, Gülizar Saritas, Ailsa Maria Main, and Maria Lykkegaard Nicolaisen. The group participates in several international consortia including GEMINI, IMiGC, and TECAC, focusing on male infertility and testicular cancer genetics.

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Lucy WeinertView profile

Associate Professor

University of CambridgeUnited Kingdom

Dr. Lucy Weinert is an evolutionary biologist and Associate Professor at the University of Cambridge, affiliated with the Transmissible Cancer Group within the Department of Veterinary Medicine. Her research focuses on bacterial pathogenesis, genome evolution, and host-pathogen dynamics. Current Position: Principal Investigator (2015–present) Previous Roles: Postdoctoral Researcher at University of Edinburgh, Imperial College London, and University College London Research Interests: Genomic mechanisms of pathogen emergence Host switches and zoonotic transmission Antimicrobial resistance evolution Vaccine development strategies Grants & Funding: Royal Society, Medical Research Council, Wellcome Trust, Newton Fund, and Global Challenges Research Fund (GCRF). Contact: Phone: +44 (0) 1223 766247 Address: Department of Veterinary Medicine, Madingley Road, Cambridge CB3 0ES, UK

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Stephanie DakinView profile

Professor

University of OxfordUnited Kingdom

Stephanie Dakin is a tenured Full Professor of Musculoskeletal Sciences at the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford, and a Senior Research Fellow at Green Templeton College. Her research focuses on identifying mechanisms of chronic inflammatory fibrosis in soft tissue joint diseases including tendinopathy, frozen shoulder, and knee arthrofibrosis to develop novel therapeutic strategies for fibrosis resolution. Her educational background includes: BVetMed from the Royal Veterinary College (RVC), University of London (2003) PhD from the RVC (completed 2012) PGCert in Teaching & Learning in Higher Education (2020) Professor Dakin's research centers on the cellular and molecular basis of soft tissue joint diseases, investigating how tissue-resident cells including fibroblasts and macrophages drive chronic inflammation and fibrosis. Her work spans from equine orthopaedics to human translational research, with particular emphasis on identifying resolution pathways in inflammatory fibrosis to develop targeted therapies for conditions like frozen shoulder and tendinopathy. Her publication record (2015-2025) shows a clear evolution from foundational studies on inflammation in tendon disease toward advanced single-cell and transcriptomic analyses of fibrosis mechanisms. Recent work leverages cutting-edge techniques to model soft-tissue diseases in vitro and identify precision therapeutic targets, with growing emphasis on stem cell dynamics and resolution biology in chronic conditions. Her scientific recognition includes: Versus Arthritis Foundation Fellowship Oxford-UCB Prize Fellowship in Biomedical Sciences Versus Arthritis Career Development Fellowship Fellow of the Higher Education Academy Professor Dakin has supervised multiple research students including Alejandro Gomez, Alexis Pointdexter, and Jiachen Lou, and served as Director of Postgraduate Taught Studies for the MSc in Musculoskeletal Sciences for eight years. Her research is funded by major grants from Versus Arthritis, NIBR Global Scholars program, Oxford-BMS, The Rosetrees Trust, NC3Rs, and UKRI. She leads the Dakin Group (Soft Tissue Joint Disease) at NDORMS, collaborating closely with Professors Andrew Carr, Christopher Buckley, and Mark Coles on translational research aimed at reducing the global burden of soft tissue joint diseases.

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Matthew MurrayView profile

Professor

University of CambridgeUnited Kingdom

Professor Matthew Murray is a Professor in the Department of Pathology at the University of Cambridge, leading the Murray Group within the Division of Cellular and Molecular Pathology. He concurrently serves as an Honorary Consultant Paediatric Oncologist at Addenbrooke's Hospital. His research centers on childhood solid tumours, with groundbreaking work on germ cell tumours (GCTs) establishing microRNA clusters miR-371~373 and miR-302/367 as universal biomarkers for malignant GCTs. Current projects investigate clonal dynamics of tumour evolution, tumour microenvironment interactions through extracellular vesicles, therapeutic targeting of microRNA pathways including the LIN28/let-7 axis, and clinical translation of serum microRNA assays for diagnosis and relapse monitoring in international trials. Professor Murray mentors PhD student Zachary Scurlock and visiting student Jessica Balls. His laboratory, embedded within the Department of Pathology on Tennis Court Road, actively contributes to prospective clinical trials for biomarker validation in germ cell tumours and neuroblastoma.

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Thomas G. BlanchardView profile

Professor

University of Maryland, BaltimoreUnited States

Dr. Thomas G. Blanchard is a Professor in the Department of Pediatrics at the University of Maryland School of Medicine. He serves as the Director of the University of Maryland Brain and Tissue Bank (UMBTB) and has held this position since 2007. His academic journey includes a PhD in Immunology from the University of Massachusetts (1991) and a JD from Case Western Reserve University (2002). Education: University of Massachusetts, B.S., Biology, 1985 University of Massachusetts, Ph.D., Immunology, 1985-1991 Case Western Reserve University, J.D., 2002 Dr. Blanchard specializes in immunology, particularly mucosal immunology, focusing on the host response to Helicobacter pylori (H. pylori) infections. His work has elucidated mechanisms of immune evasion by H. pylori and pioneered vaccine development strategies, including neonatal vaccination and systemic/mucosal delivery. Notably, he has demonstrated the roles of IL-10, Treg cells, dendritic cells, and Th17/Th1 responses in immunity. Recent research explores andrographolide (AGP) in colon cancer therapy, revealing its capacity to induce ER stress, upregulate tumor suppressor genes (PTEN, RASSF1A), and trigger apoptosis. His publications span topics like H. pylori genomics, IRAK-M signaling, and lymphoid follicle formation, reflecting interdisciplinary expertise in immunology, microbiology, and oncology. Leadership Roles: Director, University of Maryland Brain and Tissue Bank (2007–present)

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Sara O. VargasView profile

Associate Professor

Boston Children's HospitalUnited States

Sara O. Vargas is an Associate Professor at Harvard Medical School and a practicing pediatric pathologist at Boston Children's Hospital. She holds an MD from University of Vermont College of Medicine and completed fellowships in Pediatric Pathology and Anatomic/Clinical Pathology. Harvard University (Undergraduate) University of Vermont College of Medicine (Medical School) Boston Children's Hospital (Pediatric Pathology Fellowship) Brigham and Women's Hospital (Anatomic/Clinical Pathology Fellowship) Her research focuses on pediatric pulmonary pathology, interstitial lung disease, and genetic determinants of congenital disorders. She has contributed extensively to understanding pulmonary hypertension mechanisms and imaging protocols for developmental lung conditions. Her recent publications address topics like genetic variants in interstitial lung disease, vascular remodeling in pulmonary hypertension, and multiomic analyses of sudden infant death. She serves as Director of Quality and Patient Safety in the Department of Pathology, which processes over 12,000 surgical pathology cases annually. Dr. Vargas specializes in the intersection of pathology, radiology, and clinical genetics, with particular expertise in: Pediatric pulmonary hypertension Congenital lung malformations Genetic lung disease Post-transplant pathology Interstitial lung disease Pediatric oncologic pathology

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Andrew BarbourView profile

Professor

University of QueenslandAustralia

Professor Andrew Barbour is an academic general surgeon and translational researcher at The University of Queensland , specifically affiliated with the School of Medicine under the Faculty of Health, Medicine and Behavioural Sciences . He specializes in upper gastrointestinal, pancreatic, melanoma, and sarcoma surgery , with expertise in robotic and laparoscopic procedures for conditions like oesophageal cancer and soft tissue tumours. Doctor of Philosophy, The University of Queensland Faculty of Anaesthetists, Royal Australasian College of Surgeons His research integrates genomic, epigenomic, and transcriptomic data to advance precision medicine in cancer , focusing on biomarker discovery for therapy response and recurrence prediction. Key contributions include the DOCTOR trial (first PET-guided personalized therapy for oesophageal cancer) and the GAP Trial (establishing preoperative chemotherapy for pancreatic cancer). Recent publications emphasize spatial transcriptomics for thin melanoma mortality prediction, multi-omic profiling of oesophageal adenocarcinoma, and radiomics for immune signature analysis in melanoma. His work also explores small extracellular vesicle heterogeneity and genomic catastrophes as drivers in cancer. Queensland Advancing Clinical Research Fellowship for melanoma recurrence prediction Key roles in NHMRC-funded trials and MRFF MASTERPLAN trial As Chair of the AGITG Upper GI working party , he leads national cancer research initiatives. His Surgical Oncology Lab at TRI operates the Cancer Evolution Biobank , linking tumour biology with clinical outcomes.

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Jan LammerdingView profile

Professor

Cornell UniversityUnited States

Jan Lammerding is a Professor at Cornell University's Meinig School of Biomedical Engineering and the Weill Institute for Cell and Molecular Biology. His research focuses on nuclear mechanobiology, investigating how mechanical forces affect nuclear structure and function in cancer metastasis and muscular dystrophies. He has developed microfluidic platforms to study nuclear deformation and holds fellowships from BMES, AIMBE, and ASCB. Education: Diplom Ingenieur (RWTH Aachen), B.E. (Dartmouth), Ph.D. (MIT) Leadership: Director of Graduate Studies (2011-2024), Associate Director of Meinig School (2024-) Research spans nuclear envelope rupture in cancer cells, mechanotransduction pathways, and Ledercq Foundation-funded projects on laminopathies. His lab has produced 15+ articles (2023-2025) covering topics like microtubule-induced nuclear damage , 3D hydrogel migration , and mechanical stress epigenetic effects . Awards include Keith Porter Medal , NSF CAREER , and Cornell Teaching Excellence honors.

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Alan N. EngelmanView profile

Professor

Harvard UniversityUnited States

Alan N. Engelman, Ph.D. , is a Professor of Medicine at Harvard Medical School and Principal Investigator at Engelman Laboratory. He has held appointments in Pathology (1995-2009) and Medicine (2009-present) at Harvard, with concurrent roles at Dana-Farber Cancer Institute and Beth Israel Deaconess Medical Center. Education: B.S.Ch.E., Tufts University (1981) M.S., Tufts University (1985) Ph.D., Tufts University School of Medicine (1990) His research focuses on HIV-1 integration mechanisms , targeting capsid-host interactions and nuclear entry pathways . Recent studies investigate phase separation dynamics, nucleoporin engagement, and structural modeling of viral core transport. Scientific Awards: 1995: R-AXIS Golden Crystal Award 2010: NIH MERIT Award 2012: Harvard Honoris Causa MA 2014: AAAS Fellow 2016: American Academy of Microbiology Fellow Engelman has mentored numerous researchers in retrovirology, including Sooin Jang , Satya Singh , and Zachary Ingram . His work spans collaborations with institutions like Dana-Farber Cancer Institute and Beth Israel Deaconess Medical Center, focusing on structural and mechanistic aspects of HIV-1 replication.

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Xin GeView profile

Associate Professor

The University of Texas Health Science Center at HoustonUnited States

Xin Ge is an Associate Professor at the MD Anderson-UTHealth Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston, specializing in molecular medicine. He holds the Kay & Ben Fortson Distinguished Chair in Neurodegenerative Disease Research and is an adjunct faculty member in the Department of Neurobiology and Anatomy at McGovern Medical School. Ph.D. in Chemical Engineering, McMaster University M.S. in Chemical and Biochemical Engineering, Tsinghua University B.S. in Chemical Engineering, Tsinghua University Dr. Ge’s research focuses on developing biologics like monoclonal antibodies (mAbs), T-cell receptors (TCRs), and therapeutic enzymes. His lab engineers technologies such as synthetic antibody libraries, mammalian cell display, and functional selection to overcome limitations in protease inhibition and immunotherapy development. Current projects target MMP-9 for diabetic neuropathy, stroke, and SARS-CoV-2, alongside Fc engineering for enhanced immune receptor affinity. His recent publications emphasize mammalian cell-based directed evolution, protease inhibitory antibody mechanisms, and immunotherapy applications for cancer, infections, and metabolic disorders. Topics include FcγR affinity optimization, CAR-T development, and MMP-14/MMP-9 targeting for pain and disease. Maximizing Investigators’ Research Award (R35), NIGMS, 2021 NSF CAREER Award, 2015 NSERC Postdoctoral Fellowship, 2008 Dr. Ge has graduated 7 PhD and 7 MS students while mentoring 11 postdocs and 5 research scientists. His lab employs structure-aided design, repertoire deep sequencing, and recombinase-mediated transgene integration systems to engineer next-generation biologics for clinical translation.

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