Find Academic Supervisors

• Skeletal Muscle Physiology
• Mitochondrial Biology
• Metabolic Disease
• +3 more

Dr. Nicholas Broskey is an Associate Professor in the Department of Kinesiology at the College of Health and Human Performance, East Carolina University. His research bridges translational science and clinical practice, focusing on skeletal muscle physiology and mitochondrial biology to address metabolic diseases through exercise interventions. Dr. Broskey's work explores how maternal health during pregnancy programs infants' metabolic health outcomes, utilizing mesenchymal stem cell models to study developmental programming of obesity and diabetes. He combines clinical expertise in exercise prescription and metabolic assessment (e.g., hyperinsulinemic-euglycemic clamp, indirect calorimetry) with basic science techniques to evaluate mitochondrial content and function. His recent publications highlight maternal exercise effects on offspring metabolism, mitochondrial heterogeneity in racial health disparities, and bioenergetic adaptations in cancer cells. Grants from NIH, Brody Brothers' Foundation, and Duke University support his research on maternal-fetal metabolic programming and exercise transducers. Scientific Awards Outstanding Researcher or Creative Activity Award 2023-2024 Early Career Grant Challenge 2018 Endowed Postdoctoral Fellowship 2015 Best Poster 2012 Dr. Broskey actively serves on editorial boards for Clinical Experimental Obstetrics and Gynecology (2023) and International Journal of Sports Medicine (2022).

Meden F. Isaac-LamView profile

Professor

• Drug therapeutics for cancer
• Photodynamic therapy
• Triple-negative breast cancer treatment
• +10 more

Meden F. Isaac-Lam is a Professor of Chemistry in the College of Engineering and Sciences at Purdue University Northwest, where she teaches organic chemistry, biochemistry and general chemistry. Her research spans multiple interdisciplinary fields with significant contributions to cancer therapeutics and molecular imaging. Her primary research interests focus on the development and discovery of drug therapeutics for photodynamic therapy as cancer treatment and for neurodegenerative diseases, the use of MRI/MRS (magnetic resonance imaging and spectroscopy) to study brain diseases and disorders, and understanding the effect of calorie restriction in human health . Additional research areas include plastic degradation, environmental protection, and STEM education innovation. Dr. Isaac-Lam's scholarly work demonstrates a strong trend toward translational research with clinical applications, particularly in cancer treatment. Her publications show expertise in chemical synthesis, molecular imaging, and therapeutic development with a focus on practical applications for human health conditions. Senior Fulbright Scholar United States Patent No. 11,191,835 B2 for Chlorin-Vitamin Conjugates (Therapeutics for Cancer) Dr. Isaac-Lam is deeply committed to mentoring undergraduate students, believing that "mentoring is extremely critical in student success." She emphasizes individualized teaching approaches and has developed well-structured mentoring programs that consider students' career paths and intellectual abilities. Her patent work serves as an inspiration for students, demonstrating the real-world applications of chemistry research and the possibility of becoming an inventor. She leads interdisciplinary research initiatives including a project studying American military veterans afflicted with post-traumatic stress disorder (PTSD), collaborating with statisticians, social workers, psychologists, radiologists, MRI technicians and medical physics students to understand how brain molecules affect feelings and behavior.

Jean AdamsView profile

Professor

• Dietary Public Health
• Population Health
• Health Behaviors
• +3 more

Jean Adams is a Professor of Dietary Public Health at the University of Cambridge , affiliated with the MRC Epidemiology Unit and the School of Clinical Medicine . She is also a MRC Investigator and Programme Lead in Population Health Interventions. PGCert in Science Communication (University of the West of England, 2012) MSc in Health Psychology (City University, London, 2007) PhD in Epidemiology & Public Health (Newcastle University, 2004) MBBS (Newcastle University, 2001) BMedSci (Hons) in Health Psychology and Psychiatry (Newcastle University, 1998) Jean’s research focuses on population-level influences on dietary public health , examining how social, fiscal, and physical environments shape dietary behaviors. Her work includes evaluations of policies like the UK ‘soda tax’ , calorie menu labelling , and food marketing restrictions , aiming to create healthier food systems. She leads the Dietary Public Health group and contributes to global initiatives such as the Mandala Consortium and Fresh Street trials. Scientific awards and fellowships : MRC Special Training Fellowship in Health Services and Health of the Public Research (2005–2009) NIHR Career Development Fellowship (2011–2015) Faculty of Public Health Medicine and BUPA Joint Research Fellowship (2001–2004) Jean has supervised numerous grants and students, including Hannah Forde ’s research on the UK Soft Drinks Industry Levy (SDIL) and Susanna Mills ’s NIHR Doctoral Research Fellowship. She serves as Academic Editor for PLOS Medicine and leads the Population Health Interventions program at the MRC Epidemiology Unit. Her work spans interdisciplinary collaborations, including the Cambridge Global Food Security initiative, where she explores links between food environments and health outcomes.

• Developmental Biology
• Cancer Biology
• Stem Cell Research
• +5 more

Dr. Saskia Suijkerbuijk is an Assistant Professor in the Department of Developmental Biology at the Faculty of Science, Utrecht University. Her research focuses on understanding the mechanisms of cancer progression, particularly in colorectal cancer, with an emphasis on cell competition, stem cell dynamics, and metastasis formation. Her research interests include: Developmental Biology and its role in cancer progression Cell competition mechanisms in intestinal and colorectal cancer Stem cell dynamics in normal and cancerous intestinal tissue Metastasis formation and the role of the tumor microenvironment Organoid modeling of cancer progression and metastasis Dr. Suijkerbuijk's work has established important connections between developmental processes and cancer progression. Her recent publications demonstrate a consistent focus on how cell competition drives tumor growth and metastasis, with particular attention to intestinal cancer models. She has developed innovative organoid transplantation approaches to study colorectal cancer progression in vivo, providing valuable insights into the cellular and molecular mechanisms underlying metastasis formation. Her scientific contributions have been recognized through publications in high-impact journals including Nature Communications, Cell Stem Cell, and PNAS.

Francesco NeriView profile

Professor

• Epigenetics
• Aging Research
• Cancer Biology
• +5 more

Francesco Neri is a Professor at the Department of Life Sciences and Systems Biology (DBIOS) at the University of Turin, Italy. His research focuses on the epigenetic mechanisms underlying aging and cancer development, particularly in intestinal stem cells. He leads the Epigenetics of Aging & Cancer Lab located at the Molecular Biotechnology Center (MBC) "Guido Tarone" in Turin and maintains collaborations with the Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) in Jena, Germany. Professor Neri's research interests span several interconnected areas related to aging and disease: Epigenetic drift and DNA methylation changes during aging Intestinal stem cell biology and regeneration in aging Inflammaging (age-related chronic inflammation) Gut microbiome dysbiosis in elderly individuals Development of dietary interventions for healthy aging Colon cancer development and epigenetic mechanisms His research group employs cutting-edge technologies including single-cell RNA sequencing, organoid culture systems, and various genome-wide approaches (RNA-seq, ChIP-seq, ATAC-seq, Bisulfite-seq) to investigate the molecular mechanisms connecting aging with intestinal dysfunction and cancer. Recent work has revealed important connections between interferon gamma signaling, intestinal stem cell function, and tissue regeneration in aging. Professor Neri's publication record demonstrates a strong focus on aging, epigenetics, and intestinal biology, with numerous high-impact publications in journals such as Nature Communications, Cell Reports, and Nature Reviews. His work shows a clear trajectory from fundamental epigenetic mechanisms to translational applications in aging and cancer. His research has important implications for developing interventions to improve intestinal health in elderly individuals and potentially prevent age-related diseases including cancer.

Soner DoğanView profile

Professor

• Breast Cancer
• Calorie Restriction
• Molecular Biology
• +3 more

Prof. Soner Doğan is a Professor at Yeditepe University's Faculty of Medicine, Department of Medical Biology. He holds a PhD in Medical Biology from the University of Minnesota and a Bachelor's in Veterinary Science from Ankara University. His research bridges oncology, epigenetics, and metabolic regulation, with a focus on breast cancer mechanisms and calorie restriction. Research interests span: Breast Cancer Pathobiology : Investigating leptin/adiponectin signaling and epigenetic modifications in tumor development. Calorie Restriction : Examining intermittent vs. chronic dietary interventions for cancer prevention and aging. Aging and Frailty : Identifying biomarkers and molecular pathways in age-related diseases using murine models. His publications emphasize molecular oncology, with recurring themes in adipokine signaling, DNA methylation, and transcriptomic profiling. Articles frequently utilize transgenic mouse models and RNA-seq to explore metabolic and immune interactions in cancer. Awards & Honors: Professional Development Grant, Education Minnesota Foundation AICR Scholarship for Cancer Research Conference Advising & Grants : Supervised 11+ Master's/PhD theses on topics like nanoparticle drug delivery and epigenetic regulation. Secured major grants including TÜBİTAK 1001 (€395K) for breast cancer epigenetics and COST Action CA17129 for cardiovascular transcriptomics. Affiliations : Leads projects at Yeditepe’s molecular biology labs and collaborates internationally (e.g., EU-CardioRNA COST Action). Holds administrative roles as Department Coordinator and Ethics Committee member.

• Chaperone-Mediated Autophagy
• Autophagy
• Lysosome
• +4 more

Susmita Kaushik is a Professor in the Department of Developmental & Molecular Biology at Albert Einstein College of Medicine. Her research focuses on chaperone-mediated autophagy (CMA), lysosomal function, and their roles in aging, neurodegeneration, and metabolic disorders. Key Research Themes: Aging, Autophagy, Proteostasis, Lipid Biology, Neurodegenerative Diseases Institutional Affiliation: Albert Einstein College of Medicine, Department of Developmental & Molecular Biology Her work reveals how CMA regulates adipocyte differentiation, interacts with circadian rhythms, and protects against atherosclerosis. Recent publications highlight CMA activation through calorie restriction and its role in proteotoxic stress response. Collaborations with Ana Maria Cuervo and others have advanced understanding of autophagy's dual roles in disease. She contributes to autophagy assay guidelines and explores therapeutic interventions for autophagy dysfunction in Alzheimer's and Parkinson's diseases.

Christoph HandschinView profile

Professor

• Skeletal Muscle Biology
• Exercise Physiology
• Aging and Age-Related Diseases
• +4 more

Christoph Handschin is a Full Professor in Pharmacology at the Biozentrum, University of Basel, Switzerland , with a research focus on skeletal muscle plasticity, aging, and metabolic diseases since 2015. He leads a research group investigating molecular mechanisms of muscle adaptation to physiological and pathophysiological conditions. Education: PhD in Biochemistry (summa cum laude, 2001), MSc in Molecular Biology (1996), Voluntary training at Novartis (1992) Research Interests span skeletal muscle biology, aging, exercise physiology, neuromuscular diseases, and metabolic disorders. His work emphasizes PGC-1α signaling, mitochondrial dynamics, and chromatin remodeling in muscle adaptation. Recent studies explore exercise-induced chromatin changes, biomarkers of aging, and dysferlinopathy mechanisms. Key Scientific Awards include the ERC Consolidator Grant (2013) , SNSF Professorship (2006) , and MDA Scientist Career Development Award (2004) . He is a member of the American Physiological Society and European Association for the Study of Diabetes. Recent Articles highlight breakthroughs in chromatin accessibility , functional aging biomarkers , dysferlinopathy metabolism , and PGC-1α-driven muscle adaptations . His research bridges molecular mechanisms (e.g., Klf5, PER2) with systemic physiology (e.g., exercise performance, sarcopenia).

Jason FanningView profile

Assistant Professor

• Physical Activity Behavior Change
• mHealth Technology
• Gerontology
• +4 more

Jason Fanning, PhD, is an Assistant Professor in the Department of Health and Exercise Science at Wake Forest University, with a secondary appointment in Internal Medicine, Gerontology and Geriatric Medicine at Wake Forest School of Medicine. He completed his undergraduate degree and PhD in Kinesiology at the University of Illinois at Urbana-Champaign, followed by post-doctoral training at the Wake Forest Sticht Center on Aging. Dr. Fanning joined Wake Forest University in July 2019. His research specializes in technology-driven interventions for health behavior change in older adults, focusing on physical activity, diet, and chronic pain management. Key methodologies include ecological momentary assessment, mHealth applications, and randomized controlled trials. Major projects include: MORPH : mHealth-supported pain/weight management for obese older adults Time to Move : Examining real-world movement impacts on inflammation and glucose regulation ReSHAPE : Investigating stress-physical activity relationships via smartphone monitoring Dr. Fanning teaches undergraduate and graduate courses in Health Psychology (HES 312 & 733) and Statistics in Health Sciences (HES 262 & 721). He directs the Behavioral Medicine Lab, developing interventions for aging populations. His 15 most recent publications (2025) demonstrate consistent focus on: Technology-enhanced geriatric interventions Physical activity-pain relationships Novel assessment methods (accelerometry, ecological momentary assessment) Randomized trials for chronic conditions (dementia, obesity, MS) Mechanistic studies of aging physiology

Cintia S De PaivaView profile

Professor

• Dry Eye
• Ocular Surface Diseases
• Animal Models of Sjögren Syndrome
• +8 more

Cintia S De Paiva, M.D., Ph.D., is a Professor in the Department of Ophthalmology at Baylor College of Medicine and holds the Caroline Elles Endowed Professorship. She specializes in ocular surface diseases, with a focus on dry eye pathogenesis, autoimmune disorders (e.g., Sjögren syndrome), and aging-related ocular changes. Her research integrates immunology, microbiome studies, and translational medicine to improve diagnostic and therapeutic strategies for ocular surface diseases. Education: M.D. from State University of Campinas (UNICAMP), Brazil (1994) Medicine Residency in Ophthalmology at UNICAMP (1997) Ph.D. in Ophthalmology from University of São Paulo, Ribeirão Preto (2015) Research Interests: Mechanisms of dry eye disease and ocular surface dysfunction Role of microbiome in ocular inflammation and immunity Impact of aging on lacrimal gland function and autoimmune processes Therapeutic modulation of inflammatory pathways (e.g., NLRP3 inflammasome, IL-36 cytokines) Development of novel treatments targeting corneal barrier dysfunction Key Achievements: Recipient of the Caroline F. Elles Professorship (BCM, 2023) NIH-funded grants investigating microbiome modulation and age-related dry eye Published over 100 peer-reviewed articles on ocular immunology and disease mechanisms Grants: NIH-NEI: Commensal microbiota modulates ocular surface mucosal inflammation (R01EY026893) NIH/NEI: Interplay of interferon-gamma and cathepsin S in age-related dry eye (R01EY030447) DoD: Programmable microwafer drug delivery for ocular injuries (W81XWH-12-1-0616) Labs/Teams: Leads a research team focusing on ocular surface immunology and translational therapeutics at BCM's Department of Ophthalmology.

Krista VaradyView profile

Professor

• Intermittent Fasting
• Weight Loss
• Metabolic Disease
• +4 more

Krista Varady, PhD is a Professor of Nutrition in the Department of Kinesiology and Nutrition at the University of Illinois Chicago (UIC), College of Applied Health Sciences. Her office is located at 532 AHSB, 1919 W. Taylor St., Chicago, IL. With over 100 publications and two popular science books ( Every Other Day Diet and The Fastest Diet ), she has established herself as a leading expert in intermittent fasting research. PhD in Human Nutrition, McGill University (2002-2006) Postdoctoral Fellowship, University of California, Berkeley (2006-2008) BS in Nutrition and Dietetics, University of Guelph (1998-2002) Dr. Varady's research program centers on the safety and efficacy of intermittent fasting protocols for weight loss and metabolic disease reduction, particularly in populations with obesity and type 2 diabetes. Her work systematically investigates various fasting approaches including alternate day fasting, time-restricted eating, and the 5:2 diet, examining their effects on weight management, metabolic health markers, cardiovascular risk factors, and hormonal regulation. A key aspect of her research addresses common concerns about potential side effects, demonstrating that properly implemented intermittent fasting does not cause problematic changes in sex hormones or lead to eating disorders. Analysis of her recent publications (2021-2024) reveals a growing focus on clinical applications of intermittent fasting, with increasing attention to specific populations including those with type 2 diabetes and non-alcoholic fatty liver disease. Her work increasingly examines combined interventions (fasting plus exercise) and investigates physiological mechanisms underlying observed health benefits. The research spans multiple methodologies from narrative reviews and meta-analyses to rigorous randomized controlled trials. Researcher of the Year, Distinguished Scientist, Clinical Sciences, UIC (2023) Researcher of the Year, Applied Health Sciences, UIC (2019) Mead Johnson Young Investigator Award, American Society for Nutrition (2017) Malaspina Scholar Award, International Life Sciences Institute (2015) Dr. Varady's research program is supported by significant funding from the National Institutes of Health (including multiple R01 grants), the American Heart Association, the International Life Sciences Institute, and the University of Illinois. Her current projects include investigating alternate day fasting combined with exercise for NAFLD treatment, comparing time-restricted feeding versus daily calorie restriction, and examining effects of time-restricted eating on colorectal cancer risk markers. While specific students aren't listed in the provided materials, her active grant portfolio suggests she mentors graduate students and postdoctoral researchers in her laboratory.

Dudley LammingView profile

Associate Professor

• Metabolic Health
• Aging
• Dietary Restriction
• +2 more

Dudley Lamming is Associate Professor of Medicine at the University of Wisconsin-Madison, leading research on how dietary composition—particularly protein and amino acid restriction—regulates metabolic health and aging. His lab investigates mTOR signaling pathways using rodent models and biochemical approaches. Research focuses on branched-chain amino acids (BCAA) as key regulators, with recent work demonstrating that isoleucine restriction extends healthspan and lifespan. The team employs techniques including metabolomics, molecular biology, and behavioral assessments to evaluate interventions like calorie restriction and rapamycin. Current trainees include PhD student Yang Liu, with prior graduates Nicole Richardson (PhD) and Mohammed Alotaibi (MS). The lab maintains active collaborations across geroscience and metabolism fields.

Pete CalabresiView profile

Professor

• Neuroimmunology
• Multiple Sclerosis
• Demyelination and Remyelination
• +9 more

Pete Calabresi is Professor of Neurology at the Johns Hopkins University School of Medicine, where he leads a dynamic research laboratory focused on the neurobiology of multiple sclerosis (MS) and CNS demyelination. His work bridges fundamental neuroscience and clinical neurology, with a focus on understanding how immune cells impair remyelination and drive neurodegeneration. His research interests include: Neuroimmunology of MS Endogenous remyelination mechanisms Glial cell biology (astrocytes, oligodendrocytes, microglia) Neurodegeneration and axonal injury Metabolomics and biomarker discovery in neurological disease Human iPSC-based disease modeling Dr. Calabresi's recent publications reveal a strong trend toward integrating advanced technologies—such as spatial transcriptomics, CEST MRI, and iPSC models—to dissect the molecular and cellular mechanisms of CNS injury in MS. His work frequently explores immune-glial crosstalk, with a focus on T cell modulation of oligodendrocyte precursor cells and the role of reactive astrocytes in neurotoxicity. His research is generously supported by: National Institutes of Health (R01NS041435, R01NS082347, U01NS111678) Department of Defense (W81XWH1910622) National Multiple Sclerosis Society (NMSS 1907-34756, NMSS 1904-33800) Dr. Calabresi actively mentors graduate students and postdoctoral fellows, including Leslie Kirby and Jaime Gonzalez Cardona. He leads a multidisciplinary team comprising research associates, clinical fellows, laboratory managers, and research technologists. His lab's collaborative approach integrates animal models, human tissue analysis, and cutting-edge imaging to advance neuroprotective and reparative strategies for MS.

• Applied statistics
• Clinical cancer research
• Controlled clinical trials
• +5 more

Eva Skovlund is a Professor at the Department of Public Health and Nursing , Norwegian University of Science and Technology (NTNU), Faculty of Medicine and Health Sciences. Her work bridges applied statistics with clinical research in cancer, obesity, and chronic disease management. Education : PhD in Medical Statistics, University of Oslo (1990) MSc in Pharmacy, University of Oslo (1985) Research Interests : Eva focuses on applied statistical methods , clinical cancer research , controlled clinical trials , and drug safety assessment . Her work spans hypertension management in Nepal, neuro-oncology, and metabolic effects of bariatric surgery. Publication Trends : Recent articles (2021–2025) emphasize brain metastases prognosis hypertension interventions in South Asia pharmacokinetic studies in obesity statistical modeling for multimorbidity maternal and child health risks Scientific Contributions : While no specific awards are listed, her extensive peer-reviewed publications in Cancers , BMJ Open , Clinical Pharmacokinetics , and Tidsskriftet underscore her impact.

Eishi NoguchiView profile

Professor

• Genome Maintenance
• Cancer Biology
• Aging Research
• +3 more

Eishi Noguchi is a Professor in the Department of Biochemistry and Molecular Biology at Drexel University College of Medicine and Director of the Molecular & Cell Biology & Genetics (MCBG) Graduate Program. He also directs courses in Molecular & Cellular Biology & Genetics and Cell Cycle & Apoptosis. His research focuses on genome maintenance mechanisms, cancer, and aging, using mammalian cells and the fission yeast Schizosaccharomyces pombe . Education: PhD in Molecular Biology (Kyushu University, Japan, 1997) followed by postdoctoral research at The Scripps Research Institute (2000-2004). Research Interests: Investigates DNA replication challenges at difficult chromosomal regions, alcohol-induced carcinogenesis, and lifespan extension via genomic integrity preservation. Current projects include mechanisms of alcohol-mediated esophageal cancer, replication fork stability, and calorie-restricted lifespan regulation. Scientific Awards: Includes the 2022 Elias Abrutyn Mentoring Award, 2018 Faculty Launch Leadership Fellowship, and 2009 Young Investigator Award. Recognized for contributions to mentoring and cancer research. Teaching & Advising: Supervises numerous graduate students and postdocs. Notable advisees include Jasmine Peake (Assistant Professor at Lincoln University) and Adam Leman (Lead Scientist at The Good Food Institute). Labs & Affiliations: Leads the Noguchi Lab, part of the Aging Initiative at Drexel Med. Collaborates with interdisciplinary teams across departments and institutions, advancing research in replication stress and environmental genotoxicology.