Find Academic Supervisors

• Synaptic Plasticity
• Dendritic Spines
• Neuronal Signaling
• +5 more

Ryohei Yasuda serves as Scientific Director at the Max Planck Florida Institute for Neuroscience (MPFI), a premier neuroscience research institution. With over 150 publications spanning more than 15 years, Dr. Yasuda leads cutting-edge research focused on the molecular mechanisms of synaptic plasticity and memory formation. His laboratory employs advanced imaging techniques to investigate signaling dynamics at the single synapse level. Dr. Yasuda's research centers on understanding how neuronal activity triggers biochemical signaling cascades that lead to structural and functional changes at synapses. His work particularly emphasizes the role of calcium/calmodulin-dependent protein kinase II (CaMKII), brain-derived neurotrophic factor (BDNF), and other molecular players in synaptic plasticity. Using innovative two-photon microscopy, fluorescence resonance energy transfer (FRET), and fluorescence lifetime imaging (FLIM) techniques, his lab has made significant contributions to understanding how signals propagate within dendritic spines during learning and memory processes. His research bridges molecular neuroscience with cognitive function, providing insights into both normal brain function and neurodegenerative disorders. Analysis of Dr. Yasuda's recent publications reveals a sophisticated integration of advanced imaging methodologies with molecular neuroscience to study signaling dynamics at unprecedented resolution. His work increasingly explores connections between synaptic plasticity mechanisms and neurodegenerative conditions like Alzheimer's disease, while maintaining a strong focus on fundamental mechanisms of memory formation. The integration of CRISPR/Cas9 genome editing, in vivo imaging, and behavioral analysis represents the cutting-edge approach of his laboratory. Based on co-author patterns across numerous publications, Dr. Yasuda leads a substantial research team comprising postdoctoral fellows, graduate students, and research technicians. His laboratory appears well-funded through multiple research grants, likely including NIH funding given the nature of his research. The collaborative nature of his work, with frequent partnerships across institutions, demonstrates his significant standing within the neuroscience community. Dr. Yasuda's laboratory at MPFI represents a world-class facility for advanced neuroscience imaging, specializing in techniques that allow observation of molecular signaling events in real-time within living neurons. The lab's technical expertise in developing and applying novel imaging methodologies has positioned it at the forefront of synaptic physiology research, contributing significantly to our understanding of how molecular events at individual synapses translate into cognitive functions.

Scott A BarbeeView profile

Professor

• Neurodevelopment
• Neurodegeneration
• RNA Biology
• +3 more

Scott A Barbee is a Professor in the Department of Biological Sciences at the University of Denver, affiliated with the College of Natural Sciences and Mathematics. His research focuses on RNA-protein interactions in Drosophila models to study neurodevelopmental and neurodegenerative processes. He holds a Ph.D. in Cell and Developmental Biology from the University of Colorado Health Sciences Center (2004) and an M.S. in Zoology and Physiology from the University of Wyoming (1998). Key research interests include understanding the roles of RNA granules, miRNA pathways, and translational regulation in neural development and disease. His work integrates molecular genetics, cell biology, and model organism studies to explore mechanisms underlying synaptic plasticity, protein homeostasis, and stress responses. Professional affiliations include the Front Range Neuroscience Group and the RNA Society. His publications span topics from FMRP dysfunction in Fragile X syndrome to age-related protein quality control mechanisms in Drosophila. Current projects emphasize translational control in neuronal contexts and the interplay between RNA biology and neurodegeneration. While no awards are listed, his grants and advising activities are not detailed in the provided text. The Barbee Lab at the University of Denver serves as a hub for these investigations, employing cutting-edge techniques in genetics, microscopy, and biochemistry to advance understanding of RNA-based regulatory processes in neurons.

Joongkyu ParkView profile

Assistant Professor

• Synaptic Plasticity
• Memory Formation
• Alzheimer's Disease
• +2 more

Joongkyu Park is an Assistant Professor in the Department of Pharmacology at Wayne State University School of Medicine. His research investigates molecular mechanisms of synaptic plasticity underlying memory acquisition, consolidation, and extinction, with applications to Alzheimer's disease. He holds a Ph.D. in Biology from Yonsei University (2010) and completed postdoctoral training at Yale University. Dr. Park's work explores kinase-phosphatase dynamics (e.g., CaMKII, DYRK1A) in synaptic receptors and neurodegeneration. Recent studies focus on chemogenetic modulation of TARP-lipid interactions and autophagy in Troyer syndrome. His lab leverages molecular tools to develop therapeutic strategies for cognitive disorders. His publications demonstrate expertise in NMDA receptor regulation, tau aggregation, and ion channel function, emphasizing translational neuroscience.

Ismail AdeniranView profile

Senior Lecturer

• Scientific Machine Learning
• Computational Physiology
• Biological Physics
• +7 more

Dr. Ismail Adeniran is a Senior Lecturer at Manchester Metropolitan University, with a research focus on integrating Physics, Computational Science, and Scientific Machine Learning to address complex problems in cardiovascular, neurological, and musculoskeletal diseases. His academic background includes an undergraduate degree in Chemical Engineering from UMIST, an MSc in Computation, and a PhD in Biological Physics from the University of Manchester. Doctor of Philosophy (Biological Physics), University of Manchester Master of Science (Computation), UMIST Bachelor of Science (Chemical Engineering), UMIST His research expertise spans Computational Physiology, Scientific Software Development, Optimal Control, Deep Reinforcement Learning, Quantum Computing, and Mathematical Optimization. He applies these methodologies to understand pathophysiological mechanisms in conditions like Hypertrophic Cardiomyopathy, Atrial Fibrillation, and Heart Failure with Preserved Ejection Fraction, while developing therapeutic frameworks for these conditions. Recent publications emphasize in silico modeling of cardiac arrhythmias, particularly Short QT Syndrome and Atrial Fibrillation, using biophysically detailed models. His work investigates genotype-phenotype relationships, electromechanical coupling, and the impact of mutations on ion channels and myocardial mechanics. Dr. Adeniran also explores computational methods for Cryptoasset valuation, aiming to address volatility through novel quantum and classical algorithms. His full research portfolio includes collaborations in biophysical modeling, ECG analysis, and interdisciplinary approaches bridging physics, computation, and clinical applications.

Wei LiuView profile

Associate Professor

• Retinal Differentiation
• Inherited Degenerations
• Retinal Regeneration
• +4 more

Dr. Wei Liu is an Associate Professor in the Department of Ophthalmology & Visual Sciences and the Department of Genetics at Albert Einstein College of Medicine. His research focuses on elucidating the molecular and cellular mechanisms of retinal differentiation and inherited degeneration using engineered mice and human pluripotent stem cells. His work has led to the development of cone-rich human retinal organoids, recognized by the NEI Prize for progress in lab-made retinas. Key areas include retinal progenitor cell regulation, photoreceptor differentiation, and modeling macular degenerations. Professional qualifications include NIH-funded positions for postdoctoral fellows and graduate students. His research integrates genetic, molecular, and developmental approaches to bridge gaps in understanding retinal regeneration and inherited diseases like retinitis pigmentosa and glaucoma. Scientific awards include the NEI Prize acknowledging advancements in retinal organoid technology. His lab investigates transcription factors (e.g., Six3/Six6) and signaling pathways critical for retinal morphogenesis and progenitor cell maintenance, with applications toward regenerative medicine.

Michael CrickmoreView profile

Professor

• Neuroscience
• Behavioral Neuroscience
• Motivational States
• +4 more

Michael Crickmore is a Professor of Neurology at Harvard Medical School and a researcher at the F.M. Kirby Neurobiology Center at Boston Children's Hospital. His work focuses on understanding the neural mechanisms underlying motivational states and decision-making processes using Drosophila melanogaster as a model system. Dr. Crickmore completed his graduate work at Columbia University with Richard Mann and conducted postdoctoral research at The Rockefeller University with Leslie Vosshall. His research has been recognized with prestigious awards including The Harold Weintraub Graduate Student Award, a Helen Hay Whitney Postdoctoral Fellowship, and the 2009 Grand Prize Winner of the GE & Science Prize for Young Life Sciences. Dr. Crickmore's laboratory investigates how motivational states are generated and regulated in the brain. His team has made significant discoveries about neural circuits controlling mating drive, identifying specific dopaminergic and GABAergic neurons with opposing influences on motivational states. His work combines neurogenetic approaches with advanced imaging to understand how internal states influence behavior, providing insights into fundamental mechanisms conserved across species including humans. His recent publications reveal how dopamine biases decisions by limiting temporal integration and how molecular mechanisms match decision-making to motivational states, with implications for understanding disorders like ADHD, depression, schizophrenia, and addiction. Dr. Crickmore's scientific contributions include numerous publications in high-impact journals: The Harold Weintraub Graduate Student Award Helen Hay Whitney Postdoctoral Fellowship 2009 Grand Prize Winner of the GE & Science Prize for Young Life Sciences As a principal investigator, Dr. Crickmore mentors graduate students and postdoctoral fellows in his laboratory at the Neurology Research department. His research is supported by grants from major neuroscience funding agencies, though specific grant details are not provided in the available information. Dr. Crickmore's laboratory is part of the vibrant neuroscience community at Boston Children's Hospital and Harvard Medical School, where his team employs a multidisciplinary approach combining genetics, imaging, and behavioral analysis to study the neural basis of motivation and decision-making.

Mike KiebishView profile

Visiting Professor

• Lipidomics
• Metabolomics
• Metabolic Diseases
• +7 more

Mike Kiebish serves as a Visiting Scholar in the Biology Department at Boston College and Vice President of Platform and Translational Sciences at BPGbio. His multidisciplinary expertise spans molecular cardiology, pharmacology, bioorganic chemistry, and lipidomics/metabolomics, positioning him at the intersection of academic research and biotechnology innovation. His educational background includes: Postdoctoral Training at Washington University School of Medicine in Molecular Cardiology and Pharmacology, Bioorganic Chemistry, Systems Biology, Biophysics, Membrane Biochemistry, and Lipidomics/Metabolomics Ph.D. in Biology from Boston College focusing on Metabolic Neurochemistry, Neuro-oncology, Neurodegeneration, and Lipid biochemistry B.S. from Villanova University with majors in Biology and Comprehensive Science, and minors in Business and Russian Kiebish's research centers on high throughput omic technologies applied to therapeutic development for oncology, metabolic diseases, rare diseases, and neurological disorders. His pioneering work has identified novel lipokines with potent biological functions, developed spatial omic technologies for single-cell metabolite tracking, and created screening tools for protein degradation assessment. His team's implementation of Bayesian analytics has advanced target discovery and biomarker development, resulting in over 100 publications and 10+ issued patents. Analysis of his recent publications reveals a cohesive research trajectory focused on lipid signaling molecules (particularly 12,13-diHOME and related compounds) and their roles in metabolic regulation, cardiovascular function, and cancer biology. His work increasingly integrates AI-driven approaches with experimental biology, exemplified by BPGbio's NAi Interrogative Biology Platform which performs comprehensive multi-omics analysis using Bayesian causal AI models. Kiebish's leadership has contributed to multiple clinical trials for conditions including Glioblastoma, Primary CoQ10 Deficiency, Pancreatic Cancer, Epidermolysis Bullosa, and Sarcopenia. His Protein Homeostasis program, built around a First-In-Class ubiquitin conjugating enzyme (E2) based targeted protein degradation platform, represents a novel therapeutic approach with significant potential.

Bo LiuView profile

Professor

• Vascular Biology
• Inflammation
• Cell Death Signaling
• +4 more

Bo Liu is a Professor in the Department of Surgery at the University of Wisconsin–Madison School of Medicine and Public Health. With a focus on vascular pathology, his research explores molecular mechanisms of vascular inflammation, necroptosis in occlusive diseases, and biomedical material development. He directs active NIH-funded projects on RIPK3 in aneurysms and thrombosis, while advancing gene delivery systems and 3D-printed vascular grafts. Education: MS (1986, Beijing University), PhD (1993, SUNY Downstate) Mentorship: Trained 12 postdocs and graduate students including Jason Ren, Ting Zhou, and Vijayah Pilli Research interests span vascular inflammation , regulated cell death , and extracellular matrix biology , with translational applications in abdominal aortic aneurysm and venous thrombosis . His lab pioneered necroptosis inhibitors and characterized TSP1 as a key inflammatory mediator. Recent publications highlight single-cell RNA sequencing of disease heterogeneity, RIPK3 phosphorylation during cell division, and EV-mediated signaling in thrombosis. Collaborations span biochemistry, materials science, and clinical disciplines. Scientific Awards: NIH R01HL149404 (PI, 2020-2024) NIH R01 HL158073 (PI, 2021-2025) AHA Transformation Award 20TPA35490307 (2021-2023) University of Wisconsin Research Forward Grant (2022-2024) His lab integrates CRISPR gene editing , proteomics , and nanotechnology , maintaining a multidisciplinary environment with engineers and clinicians. Current projects include developing self-powered stents and characterizing pathogenic signaling networks in vascular diseases.

Karen SzumlinskiView profile

Professor

• Neuropharmacology
• Addiction
• Drug Abuse Mechanisms
• +3 more

Dr. Karen Szumlinski is a Full Professor in the Department of Psychological & Brain Sciences at the University of California, Santa Barbara (UCSB). She is affiliated with the Neuroscience Research Institute and the Department of Molecular, Cellular and Developmental Biology. Her research focuses on the biochemical mechanisms underlying drug abuse, particularly psychomotor stimulants and alcohol, emphasizing glutamate signaling and its role in addiction-related neuropsychiatric disorders. Dr. Szumlinski employs transgenic mice, viral vectors, and neuropharmacological techniques to study drug-induced behavioral changes and cognitive sequelae. Her laboratory is funded by NIH and UCSB, and she collaborates with researchers globally. She holds editorial roles in journals like eNeuro and is a member of prestigious organizations, including the American College on Neuropsychopharmacology. Dr. Szumlinski’s educational background includes a BSc and MSc from McMaster University, followed by a PhD from Albany Medical College. She completed postdoctoral training at the Medical University of South Carolina before joining UCSB in 2004. Her outreach efforts include coordinating Brain Awareness Week programs for K-6 students in Santa Barbara and Goleta.

• Calcium Signaling
• Cell Biology
• Liver Physiology
• +7 more

Michael H. Nathanson, MD, PhD, is the Gladys Phillips Crofoot Professor of Medicine (Digestive Diseases) and Professor of Cell Biology at Yale School of Medicine. He serves as Co-Director of the Yale Liver Center and Director of the Center for Cellular and Molecular Imaging, playing a pivotal role in advancing hepatology and cellular imaging research. Department: Department of Medicine (Digestive Diseases) School: Yale School of Medicine University: Yale University Research Interests: Dr. Nathanson’s research centers on calcium signaling in liver cells, particularly hepatocytes and cholangiocytes. His work explores how nuclear and mitochondrial calcium dynamics regulate liver function and contribute to diseases such as cholestasis, alcohol-associated hepatitis, and fibrosis. He investigates the molecular mechanisms of inositol trisphosphate receptors and their role in bile secretion and disease pathogenesis. Recent Research Trends: His recent publications highlight the intersection of calcium signaling, mitochondrial metabolism, and immune regulation in liver disease. Key themes include the role of cytosolic calcium in metabolic regulation, neutrophil-mediated calcium dysregulation in alcoholic hepatitis, and mitochondrial DNA in stellate cell activation. His work increasingly bridges cell biology, immunology, and metabolism. Scientific Awards and Honors: Member, Association of American Physicians (AAP) Member, American Society for Clinical Investigation (ASCI) FAPESP Fullbright Scholar Grants and Advising: Dr. Nathanson is the Principal Investigator of multiple NIH grants, including R01s, a P01 program project, and a P30 Digestive Diseases Research Core Center. He also leads a T32 training grant in Hepatology, supporting the development of physician-scientists. He directs core facilities and mentors numerous researchers, contributing significantly to academic training and collaborative science. Labs and Research Teams: He leads research through the Yale Liver Center and the Center for Cellular and Molecular Imaging, fostering interdisciplinary collaboration. His team frequently partners with experts in metabolism, immunology, and imaging, including Drs. Gerald Shulman, Fred Gorelick, and Barbara Ehrlich.

Dennis GoebelView profile

Associate Professor

• Neuroscience
• Retinal Neuroanatomy
• Biochemistry
• +3 more

Dennis Goebel is an Associate Professor at Wayne State University School of Medicine in the Department of Ophthalmology, Visual and Anatomical Sciences. His research focuses on retinal neuroanatomy, neuroprotection mechanisms, and therapeutic interventions for retinal and brain injuries linked to ischemic events. Ph.D. in Anatomy & Cell Biology (1991), Wayne State University Postdoctoral training at Sinai Hospital (Detroit) under Michael Bannon Research Interests: Dr. Goebel's work bridges biochemical/molecular cell biology with retinal toxicity models. He investigates glutamate excitotoxicity pathways, mitochondrial membrane potential dynamics, and neuroprotective peptides targeting MAGUK proteins and TrkB/NMDA receptors. Collaborations: Partnerships with Brown University, Dartmouth University, Chapman University, and University of Michigan advance his translational research in neurodegeneration and memory retention.

• Neuroscience
• Pharmacology
• Stress and Depression
• +3 more

Martine Mirrione is a Professor of Biomedical Sciences at Quinnipiac University , where she also serves as Director of Graduate MLS and BMS Programs . With a PhD in Molecular and Cellular Pharmacology from Stony Brook University and postdoctoral training at Brookhaven National Laboratory and Cold Spring Harbor Laboratory, she specializes in neuronal circuitry in stress and depression. Bachelor of Science in Biology, Marist College PhD in Molecular and Cellular Pharmacology, Stony Brook University Her research focuses on neuroinflammation , microglial dynamics , and antidepressant mechanisms , particularly through studies involving rodent models of chronic stress. She has secured institutional grants and published extensively on synaptic dysfunction and cellular metabolism in mood disorders. In 2021 alone, she contributed to studies on PFKFB3 stress markers , astrocyte morphology , and CaMKII regulation in depressive states, alongside a journal article on NMDA receptor subunits in the hippocampus. Her work bridges molecular neuroscience with translational mental health research. Faculty Scholarship and Creative Works Impact Fund grant recipient Dr. Mirrione teaches courses spanning pharmacology, neuroanatomy, and research methods while leading an active laboratory dedicated to understanding and treating stress-related neurological impairments.

Todd C. SacktorView profile

Professor

• Memory mechanisms
• Neuroscience
• Protein Kinase C
• +3 more

Todd C. Sacktor is a Distinguished Professor at SUNY Downstate Medical Center with appointments in the Departments of Physiology and Pharmacology, Neurology, and Anesthesiology. His groundbreaking research focuses on the molecular mechanisms of memory storage, particularly the role of protein kinase Mzeta (PKMζ) in long-term memory persistence. Harvard College (A.B., 1978) Albert Einstein College of Medicine (M.D., 1982) Columbia University (Neurology Residency) Howard Hughes Medical Institute (Fellowship) Sacktor's research centers on the molecular basis of memory, with his laboratory discovering PKMζ, a brain-specific protein kinase C isoform that serves as the first identified component of the core mechanism for long-term memory storage. His work has demonstrated that PKMζ is both necessary and sufficient for maintaining long-term potentiation and storing long-term memory traces, leading to methods for erasing or enhancing specific memories. His recent research reveals PKMζ's interaction with KIBRA, a postsynaptic scaffolding protein, in maintaining long-term memory. His work has significant implications for understanding Alzheimer's disease, as PKMζ is sequestered in neurofibrillary tangles found in Alzheimer's patients' brains. His publication record shows consistent high-impact research, with recent articles focusing on the KIBRA-PKMζ interaction, memory erasure mechanisms, and the evolutionary perspective of memory maintenance. His work spans molecular neuroscience, cellular mechanisms, and behavioral implications, consistently advancing our understanding of memory persistence at multiple levels of analysis. Breakthrough of the Year 2006 (Science) Sacktor has served as a grant reviewer for the NIH Learning and Memory Study Section, the Hartford Foundation, and Veterans Affairs. His laboratory personnel include Research Assistant Professors Panayiotis Tsokas and Changchi Hsieh, along with technician Andrew Tcherepanov. His research has been continuously funded, supporting investigations into the fundamental mechanisms of memory storage with potential clinical applications for memory disorders. Sacktor leads a research team investigating the molecular mechanisms of memory persistence, with particular focus on the PKMζ-KIBRA interaction. His laboratory continues to explore how these molecular mechanisms might be harnessed for therapeutic interventions in memory-related disorders, including Alzheimer's disease and other conditions involving memory impairment.

Brian Anthony KelchView profile

Professor

• Structural Biology
• Virology
• DNA Replication
• +3 more

Brian Anthony Kelch is a Professor in the Department of Biochemistry and Molecular Biotechnology at UMass Chan Medical School, affiliated with the Morningside Graduate School of Biomedical Sciences. He holds additional roles in the Interdisciplinary Graduate Program and MD/PhD Program. Kelch earned his BS in Biochemistry & Molecular Biology from Pennsylvania State University and his PhD in Biochemistry & Molecular Biology from the University of California, San Francisco. His research focuses on structural and mechanistic studies of macromolecular machines , with emphasis on viral assembly mechanisms and DNA replication/repair complexes. The Kelch Lab employs cryo-EM, biochemical assays, and biophysical approaches to investigate clamp loaders, viral packaging motors, and DNA-protein interactions. Key areas include: Conformational dynamics in bacteriophage assembly Eukaryotic vs. prokaryotic clamp loader mechanisms Thermostable viral capsid engineering DNA damage signaling pathways Kelch's publications demonstrate consistent focus on structural virology (45%), DNA replication machinery (35%), and enzyme mechanisms (20%), with recent work exploring neurodevelopmental implications of viral proteins. His lab actively recruits postdoctoral researchers and collaborates with institutions like UCSF and the International Vaccine Institute.

• Physiology
• Biophysics
• Cardiac Physiology
• +4 more

Thomas Shannon, DVM, PhD, is an Associate Professor at Rush Medical College within the Department of Physiology & Biophysics at Rush University. His research focuses on calcium signaling in cardiac myocytes, particularly the role of sarcoplasmic reticulum (SR) in excitation-contraction coupling and pathologies like heart failure. He employs biochemical, biophysical, and molecular approaches to study SR calcium regulation and its implications in normal and diseased states. Educational Background : PhD and DVM from University of Missouri Research Interests include: Calcium homeostasis in cardiac cells Ryanodine receptor function and phosphorylation Adrenergic signaling in heart failure Sarcoplasmic reticulum calcium leak Excitation-contraction coupling mechanisms Molecular biophysics of ion transport Publication Trends show a focus on cardiac physiology, calcium signaling, and excitation-contraction coupling from 1994 to 2022, with collaborations with Douglas Bers, Eduardo Rios, and other leading researchers. While no formal scientific awards are listed, his work has been cited extensively in journals like Biophysical Journal and Journal of Molecular and Cellular Cardiology . Collaborations include researchers such as Dirk Gillespie, Eduardo Rios, and Michael Fill. His laboratory at Rush University investigates SR calcium dynamics using electrophysiology and fluorescence detection methods. The full NCBI bibliography and Scopus profile are accessible via institutional links.