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Youngjae You is a Professor of Empire Innovation in the Department of Pharmaceutical Sciences at the University at Buffalo School of Pharmacy. His research focuses on Antibody-Drug Conjugates, Cancer Chemotherapy, Medicinal Chemistry, and Targeted Drug Delivery. He holds adjunct roles at the University of Oklahoma Health Sciences Center and has led numerous grants totaling over $10 million in funding. Key awards include the 2019 Professor of Empire Innovation title and multiple DoD/CDMRP grants. His work emphasizes prodrug design, photodynamic therapy, and combination therapies. Education : PhD in Pharmaceutical Chemistry, Chungnam National University (2001) MS in Pharmaceutical Chemistry, Chungnam National University (2000) BPharm, Chungnam National University (1994) Research Interests : Dr. You specializes in developing light-activatable prodrugs for targeted cancer therapies, including far-red/NIR light-activated delivery systems. His work integrates quantitative pharmacokinetic modeling, singlet oxygen dynamics, and receptor-targeted drug conjugation to enhance therapeutic efficacy while minimizing off-target effects. Key applications include bladder, breast, and ovarian cancers. Funding Highlights : NIH/NIGMS: $1.37M (2023-2027) for light-responsive drug delivery National Cancer Institute: $2.1M (2022-2027) for bladder cancer treatments DoD/CDMRP/PRCRP: $392K (2017-2020) for photodynamic-chemotherapy combinations Awards : PHF Presidential Professorship (2018) American Cancer Society Research Scholar Grant (2013) Multiple DoD/CDMRP Idea Awards Service & Grants : Serves as Principal Investigator on 8 major grants. Active reviewer for Wellcome Trust, NIH, and international funding agencies. Holds patents on BODIPY derivatives and singlet oxygen-labile linkers. Lab & Collaborations : Leads the You Lab at UB, collaborating with bioengineers and clinicians to advance photomedicine and targeted drug delivery systems. Engaged in multidisciplinary teams addressing spatiotemporal control in cancer treatments.

• Antibody-Drug Conjugates
• Cancer Chemotherapy
• Medicinal Chemistry
• +3 more

Bradley D. Olsen is a full professor in the Department of Chemical Engineering at the Massachusetts Institute of Technology (MIT), where he leads research at the intersection of polymer science, soft matter physics, and bioengineering. His work focuses on designing materials for critical applications in biotechnology, hemostasis, and sustainable polymer development while advancing fundamental understanding of polymer network mechanics and self-assembly. Education: Ph.D. in Chemical Engineering, University of California Berkeley (2007) S.B. in Chemical Engineering, Massachusetts Institute of Technology (2003) Olsen's research spans protein-based materials, block copolymer phase behavior, and mechanochemical hydrogels. He has pioneered methods for quantifying polymer network topology, developing hemostatic nanoparticles, and creating bio-inspired materials for selective biomolecular transport and medical applications. His recent publications emphasize data-driven approaches to polymer characterization and educational outreach in materials science. Scientific Awards: American Physical Society (APS) Fellow (2023) Fulbright Amazonia Scholar (2023) Alexander and I. Michael Kasser Chair in Chemical Engineering (2021) ACS Macro Letters Young Investigator Award (2021) MIT Committed to Caring Honor (2019) AIChE Owens Corning Early Career Award (2019) APS Dillon Medal (2018) Kavli Emerging Leader in Chemistry (2017) ACS Polymer Division Fellow (2016) Camille Dreyfus-Teacher Scholar (2015) Alfred P. Sloan Research Fellow (2014) NSF Career Grant (2013) NIH Postdoctoral Fellowship (2008-2009) Hertz Fellow (2003-2007) Barry M. Goldwater Scholarship (2002) Olsen has received significant grant support including NSF Career (2013) and AFOSR (2012) awards. His teaching activities include innovative international outreach like the 2025 soccer-themed science camp in Brazil. The Olsen Group at MIT explores advanced materials with applications ranging from trauma care to sustainable polymers.

• Polymer Science
• Materials Engineering
• Soft Condensed Matter Physics
• +4 more

Matthew L Becker is the Hugo L Blomquist Distinguished Professor of Chemistry at Duke University, with additional appointments in Mechanical Engineering and Material Science, and Biomedical Engineering. His research focuses on polymer chemistry, bioconjugate chemistry, molecular imaging, additive manufacturing, and degradable materials for bone, soft tissue, neural, and vascular tissue engineering. Education: B.S. from Northwest Missouri State University (1998), M.A. (2000) and Ph.D. (2003) from Washington University in St. Louis Research interests include developing tunable degradable polymers for flexible electronics, tissue engineering (bone, neural, vascular), and additive manufacturing. His group is pioneering 3D printing of bioresorbable medical devices and custom inks for biomaterials. Recent work explores stereochemistry-dependent polymer properties, mechanochromism, and machine learning-driven biomaterials design. Key applications: Drug delivery systems Biodegradable adhesives Tissue regeneration scaffolds Scientific honors include: Fellow, National Academy of Inventors (2022) Fellow, American Chemical Society (2020) Carl S. Marvel Award in Creative Polymer Chemistry (2019) Fellow, American Institute for Medical and Biomedical Engineering (2018) Fellow, Royal Society of Chemistry (2017) Biomacromolecules/Macromolecules Young Investigator Award (2015) He teaches advanced courses in mechanical engineering and polymer chemistry, with a focus on 3D printing and biomaterials. His group has developed novel medical devices including resorbable suture anchors, hernia mesh coatings, and neuroprosthetic scaffolds.

• Polymer chemistry
• Bioconjugate chemistry
• Molecular imaging
• +5 more

John E. Moses is a Professor at Cold Spring Harbor Laboratory (CSHL), where he leads the Moses Laboratory and serves as Faculty Head of the Mass Spectrometry Shared Resource for the Cancer Center. He is also a Cancer Center Member focusing on developing chemical tools for biological discovery, particularly in cancer research. Dr. Moses earned his D.Phil. in Synthetic Organic Chemistry from the University of Oxford in 2004. His academic journey includes positions as Professor of Organic Chemistry at La Trobe University (2017-2020), Level 6 Future Fellow at the Australian Research Council (2017-2021), and Reader & Associate Professor in Organic Chemistry at the University of Nottingham (2007-2017). Moses' research focuses on click chemistry, a powerful discovery method that uses robust chemical reactions to synthesize functional molecules. His lab specializes in developing and exploiting bond-forming click reactions for rapid synthesis of small functional molecules, including cancer drugs and chemical probes. They apply these molecular tools in multidisciplinary projects spanning biology and chemistry. His recent work has led to significant advances in click chemistry methodologies, including Diversity Oriented Clicking (DOC) and Phosphorus Fluoride Exchange (PFEx). These approaches have enabled the discovery of new cancer therapeutics and antibiotics effective against multidrug-resistant bacteria like MRSA. Dr. Moses has received numerous honors including the 2021 Organic Division Horizon Prize: Robert Robinson Award in Synthetic Organic Chemistry, Fellow of the Royal Society of Chemistry (2015), Thieme Chemistry Award (2011), and UK & ROI Lilly Award for Excellence in Organic Chemistry (2011). Through his work at CSHL, Moses mentors students and postdoctoral researchers while collaborating with biologists to develop Chemistry For Biology. His lab's innovative approaches have been supported by multiple grants, including those from the National Cancer Institute. The Moses Laboratory is at the forefront of click chemistry research, developing new methodologies while applying them to solve critical problems in cancer biology and antibiotic resistance.

• Click Chemistry
• Cancer Drug Development
• Antibiotic Discovery
• +4 more

Yevgeny Brudno, PhD, is an Associate Professor at the Eshelman School of Pharmacy (UNC-Chapel Hill) with a joint appointment in Biomedical Engineering (UNC and NC State University). He is a member of the UNC Lineberger Comprehensive Cancer Center and leads the Brudno Lab, which specializes in drug delivery and biomaterials for cancer immunotherapy, particularly CAR T cell therapy. Research Focus: Development of implantable biotechnologies for in vivo CAR-T cell production, biomaterials for therapeutic delivery, and click chemistry-based drug targeting. Education: PhD (unspecified institution). The lab’s research bridges chemical and biomaterials science with clinical needs, emphasizing on-demand drug release , solid tumor targeting , and autoimmune disease treatments . Recent work includes bioinstructive scaffolds and tissue-reactive drug depots , leveraging click chemistry and nanomedicine . His scientific contributions are highlighted by 15 publications (2009–2025) in fields like biotechnology, cancer immunotherapy, and epigenetics. Notable awards include the NCI MERIT Award , University Faculty Scholar (NC State), and Outstanding Teacher Award (NC State). Advising: Mentored 13 PhD and Master’s students, including Sharda Pandit (2023), Chris Moody (2021), and Emily Joe (2024). Lab announcements highlight student achievements like NSF and NIH fellowships. The Brudno Lab collaborates with UNC Lineberger and NC State, focusing on streamlining therapy production , enhancing efficacy in solid tumors , and autoimmune disease applications , supported by grants from NCI and CMI.

• Biomaterials
• Nanomedicine
• Cancer Immunotherapy
• +3 more

Raphael Franzini serves as Associate Professor of Medicinal Chemistry at the University of Utah, actively contributing to the Biological Chemistry PhD Program. His research pioneers innovative chemical approaches for therapeutic development, with dual focus on DNA-encoded library technologies and bioorthogonal drug delivery systems. His educational foundation includes an M.S. from the Swiss Federal Institute of Technology (Lausanne) and a Ph.D. from Stanford University. This training underpins his group's multidisciplinary methodology combining organic synthesis, bioconjugation, computational modeling, and advanced imaging techniques. Dr. Franzini's research program centers on two transformative areas: First, advancing DNA-encoded library screening through computational integration to identify leads for challenging targets like Tankyrase and Sirtuin 6, with recent work addressing false negatives in machine learning prediction. Second, developing novel bioorthogonal release chemistry using isonitrile-tetrazine reactions for spatiotemporally controlled drug activation, validated in zebrafish models. His group emphasizes both technological innovation and therapeutic translation, with chemistry designed to minimize off-target effects in solid tumors. Analysis of his 15 most recent publications reveals escalating integration of computational methods with experimental library screening, alongside refinement of bioorthogonal release kinetics. The work spans chemical biology, medicinal chemistry, and pharmaceutical sciences, with growing emphasis on machine learning for library data interpretation and in vivo validation of drug-release systems. Dr. Franzini maintains an active research laboratory that provides comprehensive training in cutting-edge drug discovery methodologies. His group culture prioritizes both scientific innovation and researcher development, with projects spanning from fundamental reaction kinetics to therapeutic applications. The lab's infrastructure supports organic synthesis, molecular imaging, and computational analysis for advancing precision therapeutics.

• Drug Discovery
• Medicinal Chemistry
• Bioorthogonal Chemistry
• +3 more

Christopher J. Chang is the Edward and Virginia Taylor Professor of Bioorganic Chemistry at Princeton University's Department of Chemistry. His research focuses on chemical biology, catalysis, and inorganic chemistry, with an emphasis on transition metal signaling, activity-based sensing, and drug discovery. He leads the Chang Lab, which develops innovative chemical tools to study metal-dependent biological processes, including copper's role in neurobiology and cancer, formaldehyde's role in epigenetic regulation, and redox-driven protein function. His work integrates organic, inorganic, and biological chemistry, enabling discoveries in imaging, proteomics, and precision medicine. Notable achievements include pioneering activity-based sensing platforms for copper and reactive metabolites, revealing metalloplasia in cancer, and developing copper-specific therapies. Christopher Chang has received over 50 prestigious awards, including the Guggenheim Fellowship and the Howard Hughes Medical Institute Investigatorship. His lab's infrastructure includes advanced analytical instruments, synthetic chemistry facilities, and cell culture capabilities, supported by grants from NIH, NSF, and industry partnerships. Awards: ACS Bader Award (2024), Ivano Bertini Award (2022), Blavatnik National Award (2015) Lab Focus Areas: Transition metal signaling, copper-dependent biology, formaldehyde metabolism, redox drug discovery Key Technologies: Activity-based sensors, imaging probes, bioconjugation methods

• Chemical Biology
• Catalysis/Synthesis
• Inorganic Chemistry
• +5 more

Sharon Rozovsky is a Professor in the Department of Chemistry and Biochemistry at the University of Delaware's College of Arts & Sciences, where she leads research on oxidative stress response mechanisms and protein quality control pathways. Her work bridges biochemistry, chemical biology, and structural biology with direct implications for understanding neurodegenerative diseases and viral pathogenesis. Her academic foundation includes a B.S. from Tel Aviv University (1994) and a Ph.D. from Columbia University (2000), establishing her expertise in protein dynamics and redox biochemistry. These credentials underpin her innovative approaches to studying cellular stress responses. Rozovsky's research program centers on selenoproteins—proteins containing the rare amino acid selenocysteine—and their critical roles in endoplasmic reticulum (ER) stress resolution. She investigates how membrane-bound selenoproteins like Selenoprotein S and K regulate the ER-associated degradation (ERAD) pathway, with recent work revealing their surprising autoproteolytic activity and involvement in SARS-CoV-2 replication. Her lab pioneers chemical tools including expressed protein ligation and advanced 77Se NMR spectroscopy to characterize these systems at molecular resolution. Analysis of her 2021-2025 publications shows dominant themes in selenoprotein structure-function relationships, ER stress mechanisms, and viral interactions, alongside methodological innovations in cryo-EM grid technology and NMR. This body of work demonstrates consistent focus on redox biochemistry with expanding applications in virology and structural biology. No major scientific awards or fellowships were explicitly documented in the available materials, though her research impact is evident through high-impact publications and methodological contributions. She directs the active Rozovsky Research Group, mentoring graduate students and postdoctoral researchers in biochemical and biophysical techniques. Her laboratory operations are supported by competitive funding including an NSF CAREER award (2011) focused on selenoprotein reactivity, reflecting sustained recognition of her innovative research program.

• Oxidative Stress
• Protein Quality Control
• ERAD Pathway
• +5 more

Matthew R. Jones is an Associate Professor in the Department of Chemistry at Rice University and holds the Gene and Norman Hackerman Junior Chair and Norman Hackerman-Welch Young Investigator titles. He joined Rice in 2017 after postdoctoral research at UC Berkeley under Paul Alivisatos and a PhD at Northwestern University under Chad Mirkin. His research focuses on systems-level nanoparticle assembly, plasmonics, and metamaterials, with applications in energy storage and biomedicine. Jones has pioneered techniques like 4D-STEM for catalytic nanoparticles and developed adaptive materials via strain-controlled synthesis. Education: B.S. in Materials Science and Biomedical Engineering (Carnegie Mellon University), Ph.D. in Chemistry (Northwestern University as an NSF Fellow). Key awards include the Packard Fellowship (2018) and NSF CAREER Award (2022). His lab hosts over 20 graduate students and postdocs, with notable advisees including Bukky, Zhihua Cheng, and Saxton. Research emphasizes interdisciplinary approaches: combining in-situ microscopy, ligand engineering, and computational modeling to control nanoparticle behavior. Recent studies include strain-preserved nanocatalysts (2024) and chiral superlattices (2024). Collaborations span Rice’s Center for Nanoscale Imaging Sciences and the Electrochemical Society. Lab: Jones Research Group Grants: NSF CAREER, Packard Fellowship, Rice Seed Award Publications: Over 50 peer-reviewed articles, including Science Advances (2024) and Nature Communications (2023)

• Nanoparticle Assembly
• Plasmonics
• Metamaterials
• +5 more

Adam Caparco is the DiPietro Assistant Professor of Chemical Engineering at Northeastern University, with a 25% joint appointment in the Department of Chemistry and Chemical Biology. He leads the Caparco Research Group, focusing on agricultural and environmental biotechnology, enzyme immobilization, and protein assemblies. His work integrates plant virology, nanotechnology, and molecular engineering to address sustainability challenges in agriculture and environmental remediation. He is a member of the Institute for Plant-Human Interface and holds affiliations with Northeastern’s College of Engineering and School of Arts and Sciences. Education: B.S. in Chemical and Biomolecular Engineering from UCLA (2015), Ph.D. from Georgia Tech (2020) under Julie Champion and Andreas Bommarius, followed by a USDA NIFA Postdoctoral Fellowship at UC San Diego under Nicole Steinmetz. His research spans plant immunoengineering, biomanufacturing in plants, and protein-based nanomaterials for bioremediation. Research Interests Plant excretion pathways for pathogen defense and environmental remediation Design of immobilized enzymes for green chemical synthesis Plant virus nanoparticles for nucleic acid delivery and immunity modulation Multifunctional protein engineering for sustainable agriculture Recent articles highlight advancements in plant virus-based delivery systems, enzyme immobilization strategies, and nano-enabled precision agriculture. Awards include the USDA NIFA Postdoctoral Fellowship. Caparco advises graduate and undergraduate researchers, including Julia Hilgemberg Merlin (PhD ChE), Olha Bereziuk (PhD CCB), and Paul Carter (PhD ChE). He collaborates widely and seeks to expand interdisciplinary research in plant biotechnology. Labs/Teams: Caparco Research Group (EXP 420 lab, EXP 530B office) and the Institute for Plant-Human Interface.

• Agricultural Biotechnology
• Environmental Biotechnology
• Enzyme Immobilization
• +6 more

Hyun-soon Chong is a Professor of Chemistry at the Lewis College of Science and Letters , Illinois Institute of Technology. The Chong group focuses on interdisciplinary research spanning organic synthesis, medicinal chemistry, and nuclear medicine to develop targeted therapeutics for cancer and neurodegenerative diseases. Education : B.S. from Kyung Hee University, Ph.D. from the University of North Texas Research interests include: Organic synthesis using aziridinium ions Development of bifunctional chelators for radiotherapy/imaging Bioconjugate chemistry for antibody-drug conjugates Targeted cancer therapies and diagnostics Nuclear medicine applications with isotopes like Cu-64, Y-90, and Lu-177 Key publication trends show expertise in chelation chemistry, bioconjugation, and radiopharmaceutical development. The group has advanced aziridinium ion-based methodologies and created novel agents with preclinical efficacy. Labs/teams: The Chong group specializes in synthetic strategies for enantiomerically enriched molecules and biomedical chelators. Contact: chong@illinoistech.edu

• Organic synthesis
• Medicinal chemistry
• Bioconjugate chemistry
• +7 more

Christopher B. Gorman is a Professor in the Department of Chemistry at North Carolina State University (NC State), affiliated with the College of Sciences. His research focuses on nanoscale materials chemistry, including synthesis of novel polymers and materials with tailored electronic and biological properties. He holds a Ph.D. from the California Institute of Technology (1991) and a B.A. in Computer Science and Chemistry from Drew University (1987). Education: Ph.D. in Chemistry, California Institute of Technology, 1991 B.A. in Computer Science and Chemistry, Drew University, 1987 Research Interests: Synthesis of conducting polymers for organic electronics Dynamic surfaces with self-regulating properties Drug delivery systems for biological barriers Nanomaterials for environmental remediation (e.g., phosphorus removal) Biomaterials with anti-fouling or antimicrobial functions Recent Publications: Focused on nanoscale materials for biomedical, environmental, and electronic applications. Key themes include quantum dots for antimicrobial materials, functionalized polymers for drug delivery, and surface coatings with controlled degradation. Labs/Teams: Leads the Gorman Research Group at NC State, mentoring students in nanomaterials synthesis and characterization. Current group members include Sam, Juliana, Dylan, Will, Quy, Carson, Lihan, and Ivan.

• Nanoscale Materials Design
• Conducting Polymers
• Drug Delivery Systems
• +3 more

Dr. Jung-Mo Ahn is an Associate Professor of Chemistry and Biochemistry at The University of Texas at Dallas (UTD), affiliated with the School of Natural Sciences and Mathematics. His research focuses on designing small organic molecules to modulate protein-protein interactions and peptide/protein chemistry, particularly targeting cancer therapies. He leads the Ahn Lab, which employs chemical synthesis, combinatorial chemistry, and biophysical methods to develop novel therapeutics. Education: BS in Chemistry, Seoul National University (1992) MS in Chemistry, Seoul National University (1994) PhD in Chemistry, University of Arizona (2000) Postdoctoral Associate, The Scripps Research Institute (2004) Research interests include peptide/protein secondary structure mimicry, inhibition of cancer-related protein interactions, and drug design. His lab has developed oligo-benzamide tools for biological modulation and explored LIPA inhibition in ovarian cancer. Recent work targets androgen receptors in prostate cancer and ER coregulators in breast cancer. Awards include the Thieme Chemistry Journal Award (2011) and Junior Faculty Award from the American Diabetes Association (2007). He has secured grants such as a $886,000 CPRIT award for tris-benzamide research. His work emphasizes overcoming drug resistance via novel molecular targeting strategies. Labs/Teams: Ahn Lab (specializing in medicinal chemistry and bioorganic synthesis).

• Medicinal Chemistry
• Cancer Biology
• Peptide and Protein Chemistry
• +3 more

Stephen Bradforth is a Professor of Chemistry at the University of Southern California and Senior Advisor to the Dean for Research Strategy and Development in the Dornsife College of Letters, Arts and Sciences . He earned his PhD in Physical Chemistry from the University of California, Berkeley (1992) and conducted postdoctoral research at the University of Chicago . B.A., Natural Sciences, Cambridge University (1987) Ph.D., Physical Chemistry, UC Berkeley (1992) Postdoctoral Associate, University of Chicago (1993–1996) His research focuses on ultrafast laser spectroscopy to study chemical reactions in complex environments like aqueous systems and molecular materials . Key projects include: Solar Energy Conversion : Investigating photosensitizers based on earth-abundant elements (Cu, Zn, Zr) and organic photovoltaics with BODIPY cores. DNA Photodamage : Mechanisms of cyclobutane pyrimidine dimer (CPD) formation under UV exposure, emphasizing base-stacking effects. Electronic Structure in Ethereal Solvents : Studying solvated electrons in liquid ammonia and their role in carbanion stabilization. His 15 most recent articles (2004–2024) highlight advancements in photoelectron spectroscopy , singlet fission for solar cells, and DNA damage pathways . Collaborations span medicine, physics, and engineering . Scientific Awards include the ACS Physical Chemistry Division Senior Experimental Award (2023) , STAR Awardee (2019) , Cottrell Scholar , and Fellow of APS and AAAS . He has received both Junior (2001) and Senior Raubenheimer Awards (2022) at USC. Advising has been a cornerstone, with 23 PhD students graduated and 4 current candidates. His 15 most recent publications (2012–2024) emphasize ultrafast dynamics , charge transfer mechanisms , and environmental photochemistry . Labs & Teams : The Bradforth Group operates advanced time-resolved photoelectron spectrometers , liquid microjet systems , and high-repetition-rate laser facilities . Current projects include metallic water solutions (Nature 2021), DNA photophysics (FASEB J 2011), and carbanion electronic structure in ammonia.

• Ultrafast Laser Spectroscopy
• Solar Energy Conversion
• DNA Photodamage Mechanisms
• +7 more

Neel S. Joshi is an Associate Professor in the Department of Chemistry and Chemical Biology at Northeastern University's College of Science. His research focuses on engineered living materials, microbial engineering, and synthetic biology, with applications in gut therapeutics, bioremediation, and bioplastics. He leads the Joshi Lab, which develops materials from genetically programmed microbial cells, emphasizing self-healing, environmental responsiveness, and scalability. Education and affiliations include Northeastern University's Institute for Chemical Imaging of Living Systems, where he collaborates on imaging tools for disease diagnostics. Notable projects include compostable plastics and probiotic-based therapies for childhood diarrhea. Joshi has been recognized as a TIER1 Awardee for innovative research. His work bridges biomaterials science and synthetic biology, with media coverage highlighting breakthroughs like living materials for space habitats and biodegradable plastics. Awards and grants are not explicitly listed, but his lab's funding supports interdisciplinary projects. He advises students through Northeastern's graduate programs and collaborates with industry and academic partners. The lab also explores applications in wearable X-ray shielding and light-driven chemical production in yeast biohybrids.

• Bioconjugation Chemistry
• Biomaterials
• Microbial Engineering
• +5 more