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William ZamboniView profile

Professor

• Cancer Pharmacology
• Nanomedicine
• Drug Delivery Systems
• +3 more

Dr. William Zamboni is a Professor at the UNC Eshelman School of Pharmacy and Director of the UNC Advanced Translational Pharmacology and Analytical Chemistry (ATPAC) Lab. His research focuses on translational pharmacology, optimizing anticancer therapies through pharmacokinetics, pharmacodynamics, and precision medicine. Key areas include nanoparticle drug delivery, overcoming tumor delivery barriers, and immune system interactions with nanomedicines. He collaborates with institutions like the UNC Lineberger Comprehensive Cancer Center and Carolina Institute of Nanomedicine. His lab specializes in analytical methods for drug quantification and preclinical/clinical studies of liposomal agents, antibodies, and ADCs. Research highlights include developing solid-phase separation (SPS) for nanoparticle analysis, evaluating mononuclear phagocyte system (MPS) biomarkers, and optimizing drug regimens for special populations (e.g., obesity, inflammatory diseases). The ATPAC Lab provides bioanalytical services, including LC-MS/MS assays and PK/PD modeling. Dr. Zamboni’s work emphasizes bridging preclinical findings to clinical applications, with a focus on enhancing anticancer drug efficacy and reducing toxicity.

Henning UrlaubView profile

Professor

• Proteomics
• Mass Spectrometry
• Structural Biology
• +4 more

Henning Urlaub serves as Professor at the University Medical Center Göttingen (UMG) and Research Group Leader of the Bioanalytical Mass Spectrometry group at the Max Planck Institute for Multidisciplinary Sciences. His group maintains dual operations: the primary facility at the Max Planck Institute providing proteomics services as a Core Facility, and a branch laboratory at UMG's Institute for Clinical Chemistry comprising both the Proteomics Research Group and Proteomics Service Facility. The group sustains long-term collaborations including the Center for Internal Medicine at University Hospital Frankfurt/Main. Urlaub's research specializes in high-sensitivity protein analysis using electrospray ionization (ESI) and MALDI mass spectrometry, with core projects in high-throughput proteomics, detection of post-translational modifications, quantitative protein analysis, and structural characterization of protein complexes and protein-nucleic acid interactions. Recent breakthroughs include deciphering modular assembly of mitochondrial protein factories and identifying long-lived proteins essential for egg cell maintenance, demonstrating significant contributions to cellular machinery understanding. The Bioanalytical Mass Spectrometry group actively supports the research community through its Core Facility services while pursuing clinically relevant projects at UMG. Current work focuses on mitochondrial function and reproductive biology, reflecting Urlaub's leadership in advancing mass spectrometry applications for complex biological systems.

• Electrochemistry
• Nanoscience
• Synthetic Biology
• +12 more

Kaiyu Fu is an Assistant Professor in the Department of Chemistry and Biochemistry at the University of Notre Dame, where she leads a multidisciplinary research lab at the intersection of electrochemistry, nanoscience, and synthetic biology. Her work aims to develop ultrasensitive analytical platforms for biomedical applications, particularly in point-of-care diagnostics and chronic disease management. Education: Ph.D. in Chemistry, University of Notre Dame (2018) M.S. in Polymer Chemistry, Fudan University, China (2014) B.E. in Polymer Science & Engineering, Sichuan University, China (2011) Her research focuses on three core areas: (1) nanoscale electrochemistry enabling single-entity detection; (2) electrochemical biosensors for real-time, in vivo monitoring of therapeutic agents; and (3) nanobiotechnology, including DNA nanotechnology and directed evolution of nucleic acids for precise molecular recognition. Her lab develops innovative instrumentation and materials to overcome biofouling and enhance sensor performance. The recent publications highlight a strong trend toward implantable and miniaturized sensing systems, with applications in cancer therapeutics, drug delivery, and infectious disease diagnostics. These works span advanced materials, surface engineering, and hybrid electrophotonic systems. Scientific Awards: ACS Division of Analytical Chemistry Graduate Fellowship (2018) J. Peter Grace Fellowship, University of Notre Dame (2014–2015) Kaiyu Fu advises graduate students and postdoctoral researchers, and her lab actively recruits creative and dedicated individuals. She has secured research funding to support her innovative work in biosensor development and has contributed to significant advances in electrochemical detection mechanisms, including electron transfer acceleration in nanostructured electrodes and surface charge engineering for molecular discrimination. Her collaborative work with teams at Stanford and other institutions further strengthens her research impact. The Fu lab is engaged in developing next-generation diagnostic platforms, including implantable microelectrode arrays for intratumoral pharmacokinetic monitoring and hydrogel-based aptamer switches for real-time signaling molecule detection. These projects involve interdisciplinary teams working across chemistry, engineering, and biomedical sciences.

• PET Chemistry
• Peptide Synthesis
• Synthetic Organic Chemistry
• +5 more

Dr. Sergio Dall'Angelo is a Lecturer and independent Research Fellow at the University of Aberdeen's School of Medicine, Medical Sciences and Nutrition. Holding a Ph.D. in Industrial Chemistry from Universita' Statale di Milano (2008), he established an organic/medicinal chemistry lab at the Institute of Medical Sciences in 2009 and became a Research Fellow in 2019. His research spans PET imaging, peptide synthesis, and synthetic organic chemistry. Ph.D. in Industrial Chemistry (Universita' Statale di Milano, 2008) 2012 SINAPSE Postdoctoral and Early Career Researcher Exchange Fund awardee Harvard University research visit (2012-2013) Research focus areas include: Development of novel fluorine-18 PET tracers for hypoxia and drug interactions Peptide/peptidomimetic synthesis for therapeutic applications Radiochemical methodologies and clinical-grade PET tracer preparation Recent publications highlight advancements in PET tracer development, fluorinated drug design, and peptide engineering. Key collaborations include work with Harvard University and SINAPSE network institutions. Scientific affiliations: Royal Society of Chemistry (RSC) European Society for Molecular Imaging (ESMI) SINAPSE (Scottish Imaging Network) SULSA Strategic Committee - Diagnostics and Therapeutics

Nicholas BorottoView profile

Assistant Professor

• Mass Spectrometry
• Proteomics
• Bioanalytical Chemistry
• +3 more

Nicholas Borotto is an Assistant Professor in the Department of Chemistry at the University of Nevada, Reno (UNR), within the College of Science. His research focuses on advancing mass spectrometry techniques for analyzing biomolecules, particularly proteins, by integrating methods like chemical derivatization, laser irradiation, ion mobility, and radical chemistry. His lab develops tools to study protein three-dimensional structures, post-translational modifications, and the acidic proteome. Education Postdoctoral Scholar (2016-2019), University of Michigan Ph.D., Chemistry (2016), University of Massachusetts B.S., Biochemistry (2007), Northeastern University Research Interests Borotto’s work bridges chemistry and biology, addressing both biochemical questions and methodological advancements in mass spectrometry. Current projects include: 1. Equipping a carbon monoxide laser for IRMPD studies in unconventional pressure regimes. 2. Developing photocaged probes for in vivo protein structure analysis. 3. Applying free-radical initiated peptide sequencing (FRIPS) to complex anion mixtures. Publications His recent work emphasizes trapped-ion mobility spectrometry, protein footprinting, and radical-driven peptide sequencing. Publications highlight innovations in protein conformation analysis, ion mobility separations, and gas-phase chemistry. Labs & Teams The Borotto Lab, part of UNR’s Department of Chemistry, focuses on bioanalytical mass spectrometry. The lab combines instrumentation development with biochemical applications, offering students training in analytical chemistry, proteomics, and biophysical methods.

Tom LinzView profile

Associate Professor

• Microfluidics
• Electrophoretic Separations
• Digital Assays
• +4 more

Tom Linz is an Associate Professor in the Department of Chemistry at Wayne State University, part of the College of Liberal Arts and Sciences. His research focuses on developing novel lab-on-a-chip technologies for superior biochemical measurements, integrating microfluidics with electrophoretic separations and immunoassays to study disease pathogenesis. His work aims to enhance detection limits and throughput in biomedical research. Education: B.S., Truman State University, 2007 Ph.D., University of Kansas, 2013 Postdoctoral Associate, University of North Carolina, 2013–2016 Research Support: NSF CAREER Award and NIH R35 Grant The Linz Lab’s innovations address critical health challenges through advanced bioanalytical strategies, with active recruitment of graduate students for interdisciplinary training in bioanalytical chemistry and biomedical engineering.

• Lab-on-a-Chip Technology
• Microfluidics
• Molecular Diagnostics
• +3 more

Apl. Prof. Dr. Felix von Stetten is an Associate Professor and Senior Scientist at the Laboratory for MEMS Applications within the Department of Microsystems Engineering (IMTEK) at the University of Freiburg. He also serves as an Executive Board Member at the Hahn-Schickard Institute of Microanalysis Systems. His work bridges academia and industry, focusing on lab-on-a-chip technologies, microfluidics, and energy harvesting for biomedical applications. Education: Studied Agricultural Sciences and Biotechnology at the Technical University of Munich, earned a PhD in Microbiology there. Post-2004, he joined IMTEK’s MEMS Applications Lab, later co-founding Hahn-Schickard’s Lab-on-a-Chip division in 2008, which became an independent institute in 2016 under his leadership. Research Interests: His work centers on miniaturized diagnostic systems (e.g., Lab-on-a-Disk platforms), energy harvesting for medical implants, and microfluidic applications. Key innovations include centrifugal microfluidic systems, smartphone-integrated diagnostic tools, and glucose fuel cell technologies. Publications: Over 1200 citations highlight contributions to microfluidic unit operations, digital PCR, and field-deployable diagnostics. Recent work emphasizes automation in pathogen detection and flexible lab-on-foil platforms. Awards: Not explicitly listed in provided texts. However, his leadership roles and impactful research suggest significant recognition in microsystems engineering. Advising/Grants: Leads major projects like BrainLinks–BrainTools and contributes to initiatives such as FRIAS and PlanOS. Manages interdisciplinary teams and collaborates with industry partners like Endress+Hauser and TwistDx. Labs/Teams: Oversees the Hahn-Schickard Institute for Microanalysis Systems and collaborates with IMTEK’s Application Development group. Active in spin-off ventures such as SpinDiag GmbH.

• Biochip Technologies
• Analytical Chemistry
• Genomics
• +5 more

Dr. Thomas Brandstetter is a researcher and group leader at the University of Freiburg's Department of Microsystems Engineering (IMTEK), leading the Bioanalytical Surfaces group since 2007. He holds a Ph.D. in Biology from the University of Freiburg (2000) and has extensive postdoctoral experience in biochip technologies and clinical applications. His research focuses on developing innovative bioanalytical platforms for DNA/RNA detection, protein analysis, and biomedical applications such as tumor cell capture and biofilm prevention. He has pioneered surface-attached polymer networks and hydrogel coatings to enhance biochip sensitivity and reusability. Key research areas include biochip technology, microfluidics, surface chemistry, and materials science. His work integrates interdisciplinary approaches to address challenges in diagnostics, such as point-of-care testing and in vivo diagnostics. Notable projects include hydrogel-based sensor surfaces, PCR-compatible metallic coatings, and functionalized medical wires for capturing rare cells in blood. He oversees a team of PhD students and postdocs, contributing to advancements in analytical chemistry and biomedical engineering. Dr. Brandstetter has published extensively on topics like DNA microarray platforms, NASBA amplification, and antibacterial coatings. His lab collaborates with industry partners like Genescan Europe AG and contributes to translational research through patents on biochip fabrication and medical devices. He is actively involved in teaching and mentoring, fostering the next generation of researchers in bioanalytical technologies.

• Biosensors
• Point-of-care diagnostics
• CRISPR technology
• +10 more

Hongquan Zhang serves as an Associate Professor in the Department of Laboratory Medicine & Pathology at the Faculty of Medicine & Dentistry, University of Alberta. His research program develops cutting-edge bioanalytical tools for ultrasensitive and point-of-care detection of biological targets, with a particular focus on infectious disease diagnostics. Education: Ph.D., University of Alberta (2009) M.Sc., Northwest University, Xi'an, China (1999) B.Sc., Northwest University, Xi'an, China (1997) Dr. Zhang's research explores binding-induced DNA assembly to create innovative diagnostic platforms. His laboratory specializes in developing fluorescent nanosensors for real-time detection in cellular environments, constructing target-triggered DNA nanomachines, and engineering novel affinity ligands through manipulation of functional nucleic acids. His work has made significant contributions to CRISPR-based diagnostics, particularly for SARS-CoV-2 detection, where his team has developed multiple point-of-care testing approaches that integrate nucleic acid amplification with CRISPR technology. Analysis of Dr. Zhang's recent publications reveals a strong research trajectory focused on integrating DNA nanotechnology with CRISPR systems to create streamlined diagnostic platforms. His work consistently addresses the challenge of moving complex molecular diagnostics from laboratory settings to point-of-care applications, with particular emphasis on sample preparation, signal amplification, and visual readout systems that eliminate the need for sophisticated equipment. The interdisciplinary nature of his research bridges chemistry, molecular biology, nanotechnology, and clinical medicine. Teaching: LABMP 551: Laboratory Research Methods LABMP 552: NSERC CREATE Course

Alyson E. MitchellView profile

Professor

• Food Chemistry
• Food Safety
• Plant Metabolites
• +3 more

Alyson E. Mitchell is a Professor in the Department of Food Science and Technology at the University of California, Davis. Her research focuses on food chemistry, particularly the chemical changes in fruits and vegetables, food safety, and the development of analytical methods for identifying beneficial and toxic compounds in foods. She holds a Ph.D. in Food Science from UC Davis (1996). Education: Ph.D. in Food Science, University of California, Davis (1996) Research Interests: Secondary plant metabolites and their applications in food authentication and safety. Optimization of food processing to retain beneficial compounds and reduce toxicants (e.g., acrylamide). Food-matrix interactions influencing bioavailability of nutrients and bioactives. Development of advanced analytical techniques for food analysis. Recent Research Trends: Her work spans methods for detecting amygdalin in almonds, flavonoid effects on aging, and green strategies to recover phenolic compounds from agricultural waste. She also addresses public health concerns around synthetic food dyes and processed foods. Awards: 2024: UC Davis Graduate Program Advising and Mentoring Award 2017: Fellow, American Chemical Society 2015: Fellow, Agricultural and Food Chemistry Division of the American Chemical Society 2010–2015: John Kinsella Endowed Chair in Food and Nutrition Advising & Grants: Mitchell advises graduate students in food science, with a focus on analytical and applied research. Her grants and collaborations support studies on food safety, processing innovations, and sustainable practices. Labs/Teams: Leads research teams investigating almond quality, elderberry bioactives, and food forensics at UC Davis, emphasizing interdisciplinary approaches to food science challenges.

Liam HeaneyView profile

Senior Lecturer

• Bioanalytical Science
• Analytical Chemistry
• Clinical Diagnostics
• +5 more

Liam Heaney is a Senior Lecturer in Bioanalytical Science at Loughborough University's School of Sport, Exercise & Health Sciences. He joined in 2018 through the Loughborough Excellence 100 scheme and was promoted in 2022. His expertise lies in high-throughput metabolite biomarker analysis using mass spectrometry, with applications in clinical diagnostics, sports anti-doping, and exercise performance monitoring. He holds a BSc/MSc in Sport and Exercise Science/Exercise Physiology and a PhD in Analytical Chemistry from Loughborough University. Research Interests: Development of analytical methods for small molecule metabolites Clinical and sports-related biomarker discovery Gas/Liquid Chromatography-Mass Spectrometry applications Anti-doping analysis and ethical biomonitoring Publications: Liam's work emphasizes metabolomics and ambient ionization techniques, contributing to both clinical and sports science. Recent studies focus on cannabidiol pharmacokinetics, SCFA supplementation, and TMAO metabolism in health/disease. Recipient of The Analytical Scientists 40 Under 40 Power List (2022) Labs/Teams: Active in Sport Performance and Lifestyle for Health & Wellbeing research groups. Collaborates with the John van Geest Biomarker Facility (Leicester) and NIHR Cardiovascular Biomedical Research Centre.

Patrick GunningView profile

Professor

• Biological Chemistry
• Organic Chemistry
• Protein-Protein Interactions
• +7 more

Patrick Gunning is a Professor at the University of Toronto (Mississauga campus), specializing in Biological Chemistry and Organic Chemistry. His research focuses on developing small molecule architectures to manipulate protein complexation events, particularly targeting aberrant protein interactions in diseases like cancer. Key areas include STAT3/STAT5 inhibition, histone deacetylase (HDAC) modulation, and molecular design strategies for cancer therapies. Research interests emphasize understanding protein-protein interaction 'hot spots' and designing drugs to suppress or enhance specific gene expressions. His work explores both organic and inorganic drug-like scaffolds to regulate cellular signaling pathways. Recent studies highlight novel treatments for leukemia, lymphoma, and brain metastases through targeted protein degradation and metabolic pathway manipulation. Over 50 publications demonstrate expertise in oncology, epigenetics, and drug discovery. Notable contributions include HDAC6-selective inhibitors, PROTAC-based degraders, and fluorine NMR methodologies for protein analysis. His interdisciplinary approach bridges organic chemistry, biochemistry, and clinical applications in precision medicine. Current projects investigate molecular mechanisms underlying cancer growth, with a focus on STAT signaling pathways and metabolic vulnerabilities. The lab also pioneers innovative drug delivery strategies using advanced spectroscopic techniques and chemical synthesis platforms.

Nathan WittenbergView profile

Associate Professor

• Bioanalytical Chemistry
• Membrane Biophysics
• Lipid Oxidation
• +6 more

Nathan Wittenberg is an Associate Professor in the Department of Chemistry at Lehigh University , where he has been since 2016. His research focuses on bioanalytical chemistry and biomembrane interactions , particularly lipid bilayer dynamics and protein-lipid interactions crucial to nervous system function. Education: B.S. in Chemistry (University of Minnesota), Ph.D. in Chemistry (Pennsylvania State University) His work investigates: Modulation of protein-lipid interactions by membrane structure/composition Lipid oxidation effects on membrane properties and immune interactions Antibiotic resistance mechanisms in bacterial outer membrane vesicles Microfluidic and nanofabrication approaches for membrane analysis Recent publications highlight trends in biomembrane engineering , oxidized lipid dynamics , and extracellular vesicle characterization . Current students include Dane Santa (NSF Graduate Research Fellow) and Aarshi Singh . Awards include: NSF Graduate Research Fellowship (for student Dane Santa) Lab facilities span multiple Mudd Building locations (657, 589) with equipment for optical microscopy , mass spectrometry , and nanocontact printing . Collaborations bridge biochemistry , medical research , and engineering disciplines.

• Bioanalytical Chemistry
• Molecular Imprinting
• Biosensors
• +9 more

Sergey A. Piletsky is a Professor of Bioanalytical Chemistry and Research Director in the School of Chemistry at the University of Leicester, UK. He leads the Leicester Biotechnology Group and has previously held leadership roles at Cranfield University. His research is highly interdisciplinary, focusing on molecularly imprinted polymers and biosensor development for clinical and environmental applications. His research interests include: Molecular Imprinting and Biomimetic Polymers Biosensors and Electrochemical Detection Computational Design of Receptors Environmental and Clinical Diagnostics Reduction of Animal Testing via Synthetic Antibody Alternatives Nanomaterials and Polymer Chemistry The recent publications (2023–2025) highlight a strong trend in developing practical, portable, and sensitive sensors using molecularly imprinted polymers for detecting contaminants like bisphenol A and glyphosate, as well as advancements in synthesis protocols and nanomaterial integration. His work bridges chemistry, materials science, and environmental health. Scientific awards and recognitions include: JSPS Fellowship DFG Fellowship Leverhulme Fellowship Royal Society Wolfson Research Merit Award Recognition from the President of Ukraine DSc from Cranfield University Sergey Piletsky has supervised numerous students and collaborators, including Elena Piletska, Tetyana Sergeyeva, and Kal Karim. His research has been funded by 11 EU projects and major UK and international agencies such as MRC, EPSRC, Wellcome Trust, and NOAA, as well as industrial partners. He has established global collaborations with experts like Prof. Karube (Tokyo), Prof. Wolfbeis (Regensburg), and Prof. Turner (Cranfield). He leads the Leicester Biotechnology Group, which focuses on innovative solutions in analytical biotechnology, sensor development, and sustainable alternatives to biological receptors. The team integrates experimental and computational approaches to design next-generation diagnostic tools.

Joseph RowerView profile

Academic

• Pharmacokinetics-Pharmacodynamics (PK-PD) Relationships
• Bioanalytical Methods Development
• Pediatric Clinical Pharmacology
• +7 more

Dr. Joseph Rower is a Research Assistant Professor in the Department of Pharmacology and Toxicology and Adjunct Assistant Professor in Pediatrics at the University of Utah's College of Pharmacy. He serves as Associate Director of the Center for Human Toxicology. Undergraduate: California Lutheran University, BS in Chemistry and Mathematics Doctoral: University of Colorado Anschutz Medical Campus, PhD in Pharmaceutical Sciences Postdoctoral Fellowships: Systems Biology at University of Colorado, Antiviral Pharmacology at University of Colorado, and Pediatric Clinical Pharmacology at University of Utah Dr. Rower's research focuses on pediatric pharmacology , particularly validating bioanalytical methods for small blood volumes to improve clinical care for children. His lab explores personalized dosing strategies , tacrolimus in pediatric transplantation , (val)ganciclovir for congenital cytomegalovirus , and cannabis pharmacokinetics in adolescents . Collaborative work spans preclinical models, clinical trials, and pharmacometric modeling. Recent publications emphasize pediatric pharmacokinetic-pharmacodynamic relationships , bioanalytical innovations , and personalized medicine applications in diverse areas including infectious disease , neurology , and critical care . Scientific Awards Board-certified clinical pharmacologist (Diplomate of the American Board of Clinical Pharmacology) Dr. Rower's lab within the Center for Human Toxicology integrates bioanalysis and pharmacometrics to identify patient-specific factors affecting drug pharmacokinetics. Collaborations include Dr. Albert Park (pediatric ENT), Dr. Chris Reilly's team (TRP channels and pulmonary toxicology), and international partners via the University of Utah's cores.