Find Academic Supervisors

Vivek ShenoyView profile

Professor

• Mechanobiology
• Multiscale Modeling
• Biomaterials
• +6 more

Vivek Shenoy is the Eduardo D. Glandt President's Distinguished Professor at the University of Pennsylvania, with primary appointments in the Department of Materials Science and Engineering and secondary appointments in Bioengineering and Mechanical Engineering and Applied Mechanics. He leads the Multiscale Mechanobiology and Biomaterials Laboratory, which focuses on developing theoretical frameworks and numerical methods to understand complex biological and engineering systems across multiple length scales. Shenoy's research spans mechanobiology, chromatin organization, cell mechanics, and biomaterials. His work addresses the fundamental challenge of modeling how small-scale cellular phenomena couple with long-range tissue-level interactions across micrometers to centimeters. By integrating insights from soft matter physics, solid mechanics, chemistry, and applied mathematics, his group develops multiphysics continuum and mesoscale theories to elucidate mechanisms controlling both biological and engineering systems. His recent publications demonstrate an increasing focus on nuclear mechanics, chromatin organization, and the interplay between mechanical forces and gene regulation. Analysis of Shenoy's publication record reveals a strong interdisciplinary approach, with high-impact papers spanning biophysics, materials science, and cell biology. His work shows consistent evolution from fundamental mechanics of materials to complex biological systems, with recent emphasis on the mechanical regulation of chromatin architecture, cell migration dynamics in 3D environments, and mechanotransduction in development and disease. His publications appear regularly in top journals including Nature, Science, and their affiliated publications, demonstrating significant influence across multiple fields. Eduardo D. Glandt President's Distinguished Professor Multiple publications in Nature, Science, and PNAS Active research program with publications through 2025 Shenoy actively mentors students and postdocs through his laboratory, with numerous co-authored publications indicating strong mentorship. His research program appears to be well-funded through multiple grants supporting his work in mechanobiology and biomaterials. The Multiscale Mechanobiology and Biomaterials Laboratory maintains active collaborations across disciplines and institutions, reflecting the interdisciplinary nature of his research. The Multiscale Mechanobiology and Biomaterials Laboratory, housed within the Department of Materials Science and Engineering at the University of Pennsylvania, serves as the primary research hub for Shenoy's work. The lab maintains an active presence on social media (Twitter: @ShenoyLab) for updates on activities and publications. Their research approach combines theoretical modeling with experimental validation to address fundamental questions at the interface of mechanics, materials science, and biology.

Alexis BattleView profile

Associate Professor

• Genomics
• Machine Learning
• Computational Biology
• +3 more

Alexis Battle is an Associate Professor at Johns Hopkins University with appointments in Biomedical Engineering , Computer Science , and Genetic Medicine (secondary). She directs the Malone Center for Engineering in Healthcare and serves as Deputy Director of the Data Science and AI Institute . Educated at Stanford University (PhD in Computer Science, 2013), Battle transitioned to academia after leadership roles at Google. Research Focus: Battle’s work bridges genomics and machine learning , emphasizing the impact of genetic variation on human health. Her lab develops tools like Watershed to predict functional effects of rare variants, aiming to enhance rare disease diagnosis. Key themes include non-coding DNA analysis , personalized genomics , and systems biology , with applications in cardiovascular disease and neurodegenerative disorders . Publications & Awards: Over 60 peer-reviewed articles in journals like Nature , Science , and Genome Biology , with recent emphasis on single-cell transcriptomics , multiomics integration , and telomere biology . Recipient of the President’s Frontier Award (2022), Microsoft Investigator Fellowship (2019), and Searle Scholar (2016). Scientific Awards: 2022 President’s Frontier Award 2019 Microsoft Investigator Fellowship 2019 Johns Hopkins Discovery Award 2017 Johns Hopkins Catalyst Award 2016 Searle Scholar Advising & Funding: Mentors 11 PhD students, 3 undergraduates, and postdoctoral fellows. Her research is funded by NIH, Searle Scholars, and institutional grants. The Battle Lab collaborates on projects like the GTEx Consortium , focusing on gene regulation and clinical genomics .

Andrew SpakowitzView profile

Professor

• Chromosomal organization and dynamics
• Protein self-assembly
• Polymer membranes
• +7 more

Andrew Spakowitz is a Professor of Chemical Engineering, Materials Science and Engineering, and by courtesy, Applied Physics and Chemistry at Stanford University. He currently serves as the Senior Associate Dean for Research and Faculty Affairs and holds the Tang Family Foundation Chair of the Department of Chemical Engineering. His academic career at Stanford spans from Assistant Professor (2006-2014) to Associate Professor (2014-2020) and now Professor since 2020. Dr. Spakowitz earned his PhD in 2004, MS in 2001 from the California Institute of Technology, and his BS in Chemical Engineering from the University of Wisconsin, Madison in 1999. He completed postdoctoral training in Molecular and Cell Biology and Biophysics at UC Berkeley from 2004-2006. His research focuses on theoretical and computational approaches to understanding biological processes and complex materials. The Spakowitz lab addresses fundamental chemical and physical phenomena through four main research themes: chromosomal organization and dynamics, protein self-assembly, polymer membranes, and charge transport in conducting polymers. His group employs diverse theoretical and computational methods including analytical theory of semiflexible polymers, polymer field theory, continuum elastic mechanics, Brownian dynamics simulation, equilibrium and dynamic Monte Carlo simulations, and reaction-diffusion modeling. Analysis of his recent publications reveals a strong emphasis on epigenetics and chromatin dynamics, with significant work on DNA methylation patterns, nucleosome clustering, and chromosome organization. His research also extends to polymer physics applications in biological systems, particularly in respiratory diseases, water purification membranes, and bacterial phage interactions with human mucus. Tang Family Foundation Chair of the Department of Chemical Engineering Professor Spakowitz mentors several graduate students and postdoctoral scholars in the Chemical Engineering and Materials Science departments. His lab members work on diverse projects spanning from chromatin dynamics to polymer membranes for water purification. He teaches multiple courses including CHEMENG 120B (Energy and Mass Transport), CHEMENG 340 (Molecular Thermodynamics), CHEMENG 466 (Polymer Physics), and CHEMENG 467 (Physics of Biomacromolecules). The Spakowitz lab operates from Clark S295 at Stanford University, conducting theoretical and computational research that bridges chemistry, physics, biology, and engineering disciplines to address complex problems across multiple length and time scales.

Jenny OuyangView profile

Associate Professor

• Endocrinology
• Urban Ecology
• Physiological Adaptation
• +4 more

Jenny Ouyang is an Associate Professor in the Department of Biology at the University of Nevada, Reno , where she also serves as Director of the Ecology, Evolution and Conservation Biology graduate program. She earned her B.S. and B.A. from the University of California, Irvine (2007), followed by M.A. and Ph.D. in Ecology and Evolutionary Biology from Princeton University (2009, 2012). Her research focuses on the ecology and evolution of physiological systems , particularly how hormonally regulated traits enable organismal adaptation to environmental changes like urbanization , light pollution , and endocrine stress responses . Education: Ph.D., Ecology and Evolutionary Biology, Princeton University (2012) M.A., Ecology and Evolutionary Biology, Princeton University (2009) B.S., Biology, University of California, Irvine (2007) B.A., French, University of California, Irvine (2007) Her work integrates neuroendocrine mechanisms with ecological contexts to understand phenotypic flexibility and epigenetic adaptation in birds. Recent projects examine how artificial light at night disrupts circadian rhythms, hormonal profiles, and parental behaviors across urban-rural gradients. She has secured major grants including the NSF CAREER award (2022) for studying urbanization and NIH COBRE funding (2017) as part of a neuroscience team. Key collaborations include Dr. Maria Echeverry at Universidad Pontificia Javeriana in Colombia through her 2023 Fulbright award . The Ouyang Lab combines natural and laboratory experiments to investigate stress physiology, with recent papers analyzing glucocorticoid responses to urbanization, gene expression patterns under light pollution, and epigenetic reorganization in response to environmental stressors. Her publications span top journals like Proceedings of the Royal Society B , Biology Letters , and Ecology Applications , where her 2022 paper on lead pollution and reproduction was highlighted by ESA and Swedish Radio. Scientific Awards & Recognition: US Fulbright Scholars Award (2023) NSF CAREER grant (2022) NIH COBRE grant (2017) as team member Advising students like Valentina Alaasam (NSF GRFP awardee) and Ivan Celso Carvalho Provinciato (Dean's Merit Fellowship)

Britt AdamsonView profile

Associate Professor

• Stress Response Networks
• DNA Damage Response
• Genome Editing
• +3 more

Britt Adamson is an Associate Professor in the Department of Molecular Biology and the Lewis-Sigler Institute for Integrative Genomics at Princeton University, where she serves as Director of the Undergraduate Program in Quantitative and Computational Biology. Her lab investigates molecular networks in human cells with focus on stress response mechanisms and genome editing technologies. She received her B.S. in Biology from the Massachusetts Institute of Technology (2005) and Ph.D. in Genetics and Genomics from Harvard University (2012), followed by postdoctoral training at UCSF under Jonathan Weissman supported by a Damon Runyon Cancer Research Foundation Fellowship. Adamson's research centers on how cells organize stress response networks during DNA damage and endoplasmic reticulum stress, developing CRISPR-based functional genomics and single-cell sequencing tools to map molecular behaviors. Her work bridges fundamental cell biology with therapeutic applications in genome editing. Analysis of her 15 most recent publications reveals dominant themes in precision genome editing (prime/base editing optimization) and systematic dissection of DNA repair pathways through combinatorial CRISPR screening. Her lab consistently integrates computational approaches with high-resolution experimental techniques to uncover context-dependent cellular behaviors. Her scientific recognitions include: Damon Runyon Cancer Research Foundation Postdoctoral Fellowship Princeton IP Accelerator Award (2025) STAT Who to Know: 10 Scientists leading a new generation of gene editors (2024) Adamson actively mentors eight graduate students (including alumni Ann Cirincione and Jun Hussmann) and two postdocs, with research funded through institutional awards and collaborative grants. Her lab's technological developments have enabled projects spanning virology, immunology, and developmental biology. The Adamson Lab operates within Princeton's Lewis-Sigler Institute for Integrative Genomics, fostering an interdisciplinary environment that merges cell biology, genomics, and computational science. Current projects focus on improving prime editing efficiency and understanding stress response adaptation in disease contexts.

Fei-Fei LiView profile

Professor

• Artificial Intelligence
• Machine Learning
• Deep Learning
• +5 more

Fei-Fei Li is the Sequoia Capital Professor in Computer Science at Stanford University and Founding Co-Director of the Stanford Institute for Human-Centered AI (HAI). She holds courtesy appointments in the Graduate School of Business and is a Senior Fellow at HAI. Her work bridges AI research with interdisciplinary applications in healthcare, robotics, and policy. Dr. Li pioneered the ImageNet dataset, instrumental in the AI revolution, and co-founded World Labs to advance spatial intelligence and generative AI. Education: B.A. in Physics, Princeton University (1999) Ph.D. in Electrical Engineering, Caltech (2005) Doctorate (Honorary), Harvey Mudd College (2022) Research Interests: AI ethics, computer vision, robotic learning, healthcare applications, and human-AI collaboration. Her teams developed frameworks like MOMA for activity recognition and BEHAVIOR for embodied AI benchmarks. She advocates for diversity in tech and co-founded AI4All to mentor underrepresented students. Key Contributions: ImageNet and ImageNet Challenge Stanford Vision and Learning Lab (SVL) Policy advisory roles for U.S. Senate, UN Secretary-General, and California Governor Labs & Initiatives: Leads the People, AI & Robots Group (PAIR), Partnership in AI-Assisted Care (PAC), and the Human-Centered AI Institute. Her work emphasizes ethical AI deployment and societal impact. Awards: VinFuture Prize (2024), IEEE Fellow, National Academy memberships (Engineering, Medicine, Arts & Sciences), and recognition as one of Time’s AI100 Influencers.

Kora DeBeckView profile

Professor

• Substance Use
• Drug Policy
• Health Policy
• +3 more

Kora DeBeck is a Distinguished Professor of Substance Use and Drug Policy in the School of Public Policy at Simon Fraser University, a CIHR Applied Public Health Chair, and Dorothy Killam Fellow. She is also a Research Scientist with the BC Centre on Substance Use and Principal Investigator of the At-Risk Youth Study (ARYS), a longitudinal cohort tracking over 1,200 street-involved youth. Her research focuses on substance use policy, health services for marginalized populations, and the structural drivers of drug-related harms. She has published over 200 peer-reviewed articles challenging ineffective drug enforcement models and advocating for policy reforms. Recent publications analyze trends in opioid use, harm reduction during the COVID-19 pandemic, drug decriminalization, and youth-focused interventions. Her work consistently addresses social inequities through data-driven approaches to the toxic drug crisis. CIHR Applied Public Health Chair Dorothy Killam Fellow Michael Smith Health Research BC Scholar Award Distinguished SFU Professorship She has secured over $50 million in research funding, including $21M as principal investigator for ARYS. Her lab collaborates with healthcare providers, community organizations, and policymakers to translate research into practice.

Jennifer A. SmithView profile

Associate Professor

• Genetic Epidemiology
• Epigenomics
• Aging
• +4 more

Jennifer A. Smith, PhD, MPH is an Associate Professor of Epidemiology and Research Associate Professor of Survey Research at the University of Michigan School of Public Health . She also serves as Director of the Certificate in Public Health Genetics and is Assistant Director of the Cohort Development working group for U-M Precision Health and the Michigan Genomics Initiative. Education: PhD, Epidemiology, University of Michigan (2011) MA, Statistics, University of Michigan (2009) MPH, Health Management and Policy, University of Michigan (2005) BS, Biological Sciences, Cornell University (2001) Research Interests: Dr. Smith is a genetic epidemiologist whose work lies at the intersection of genomics, epigenomics, and social epidemiology . She investigates how genetic, epigenetic, and transcriptomic variation influence age-related chronic diseases such as cardiovascular disease, hypertension, dementia, and cognitive decline. A major focus is understanding how social, psychosocial, and neighborhood determinants interact with genetic risk to shape socioeconomic and racial/ethnic health disparities . Research Projects: Her work leverages large, multi-ethnic cohorts including the Health and Retirement Study (HRS), GENOA, SWAN, MESA, and LASI. She is a core faculty member of the Center for Social Epidemiology and Population Health (CSEPH) , and affiliated with MiCDA, the Center for Midlife Science, and the PNG Program . She also collaborates with leading consortia such as CHARGE and TOPMed. Selected Trends in Publications: Her recent work (2022–2025) emphasizes epigenetic mediation of social determinants on cardiovascular and cognitive health, polygenic risk scores across diverse ancestries , and multi-omics integration in aging and disease. These studies consistently highlight how social environments and genetic architecture jointly influence health outcomes across populations. Contact: Email: smjenn@umich.edu Office: 734-615-9455 Address: 2631 SPH I, 1415 Washington Heights, Ann Arbor, MI 48109

Weiqiang ChenView profile

Professor

• Lab-on-a-Chip
• Organ-on-Chip
• Biomaterials
• +7 more

Weiqiang Chen is a Professor of Mechanical and Biomedical Engineering at New York University's Tandon School of Engineering and Director of Research and PhD Programs. He holds a joint appointment at NYU Langone's Perlmutter Cancer Center as a Faculty Member of the Tumor Immunology Research Program. B.S. in Physics (Nanjing University, 2005) M.S. in Electrical Engineering (Shanghai Jiao Tong University, 2008) M.S. in Electrical and Computer Engineering (Purdue University, 2009) Ph.D. in Mechanical Engineering (University of Michigan, 2014) His research focuses on Lab-on-a-Chip , Organ-on-Chip systems, Biomaterials , and Mechanobiology , with applications in cancer biology, stem cell engineering, and immune monitoring. He pioneers microfabrication technologies for real-time observation of cellular interactions, including CAR T-cell immunotherapy efficacy and tumor microenvironment dynamics. Recent grants include NSF funding for leukemia bone marrow niche modeling, NIH Trailblazer Awards for glioblastoma immunotherapy research, and collaborations with the Arthritis Foundation for synovium-on-chip rheumatoid arthritis studies. His work has been supported by over $2M in federal and institutional research funding. National Science Foundation (NSF) grants for leukemia-on-chip and glioblastoma modeling National Institutes of Health (NIH) awards for immunotherapy research American Heart Association fellowships and institutional training programs Chen's scientific awards include the American Heart Association Fellow distinction, multiple Young Investigator Awards from Lab on a Chip and Biomedical Engineering Society, and recognition for his dissertation on nanotopography in stem cell differentiation. He leads the Applied Micro-Bioengineering Laboratory (AMBL) , which develops microphysiological systems for drug testing and personalized medicine. His team has created the first immunocompetent leukemia-on-a-chip for CAR T-cell therapy screening and glioblastoma models that enable patient-specific immunotherapy validation.

Margaret BublitzView profile

Associate Professor

• Perinatal Mental Health
• Integrated Behavioral Health
• Mindfulness-Based Interventions
• +6 more

Margaret Bublitz is Associate Professor at Brown University with joint appointments in the Department of Psychiatry and Human Behavior , Department of Medicine , and Department of Obstetrics and Gynecology . She holds secondary appointments at the School of Public Health as Senior Investigator and Behavioral and Social Sciences faculty member. Dr. Bublitz earned her PhD in Clinical Psychology (2010) from the University of British Columbia, followed by postdoctoral training in Cardiovascular Behavioral Medicine at Brown Medical School. Her research focuses on: Psychological stress pathways to adverse perinatal outcomes Maternal childhood maltreatment effects on neurobiology Mindfulness interventions for hypertension and preterm birth prevention Her 15 most recent publications demonstrate expertise in perinatal mental health , sleep-disordered breathing , HPA axis regulation , and fetal neurodevelopment , with significant collaborations in neuroendocrinology and maternal-infant health disparities . Scientific recognition includes: 2024-2025 Global Fulbright Scholarship 2022 Brown Early Career Research Achievement Award Multiple NIH and foundation grants exceeding $6 million Bublitz leads NIH-funded projects examining mechanisms of mindfulness training (R01HL157288) and serves as mentor in the MORPHE Trial for digital maternal health innovations. She is a licensed psychologist and active member of Brown's Stress, Trauma and Resilience (STAR) Institute and Mindfulness Center .

• Cell Biology
• Developmental Biology
• Neuroscience
• +3 more

Callista Yee will join the University of British Columbia as an Assistant Professor in the Department of Zoology (Faculty of Science) starting September 2025. Her research focuses on decoding molecular mechanisms governing nervous system development and synaptogenesis using Caenorhabditis elegans as a model organism. Research Focus Dr. Yee's work investigates: Transcriptional programs activated by neuronal activity Role of Groucho co-repressors in cellular switches Proteostasis and stress resilience in neurons Molecular regulation of synapse formation Publication Trends Her recent articles (2017–2025) span developmental biology, neuroscience, and molecular genetics, with a consistent emphasis on C. elegans as a model system. Key themes include transcriptional regulation of cell invasion, protein degradation tools, and aging-related pathways.

• Immunology
• Virology
• Inflammation
• +5 more

Santiago F. González is a Group Leader at the Institute for Research in Biomedicine (IRB) in Bellinzona, Switzerland, and an extraordinary professor at the University of Italian Switzerland (USI). He earned dual PhDs in microbiology (University of Santiago de Compostela, Spain) and immunology (University of Copenhagen, Denmark), followed by postdoctoral work (2007–2011) at Harvard Medical School's Immune Disease Institute under Michael Carroll. PhD in Microbiology, University of Santiago de Compostela PhD in Immunology, University of Copenhagen His research focuses on immune system dynamics during respiratory viral infections, vaccination, and cancer metastasis. Key areas include influenza recognition , lymph node inflammation , and immune cell behavior in vivo. He pioneered studies on C-type lectin receptors (e.g., SIGN-R1) in viral immunity and epigenetic modulators for inflammation. Recent publications highlight his work in epigenetic drug development , nanovaccines , and computational tools for immune cell tracking. His group uses two-photon intravital microscopy and spatial-temporal modeling to dissect immune responses. Scientific awards include three EU Marie Curie Fellowships (2004–2013), enabling his transition to independent research. His collaborations span Harvard, USI, and European institutions, with grants from the EU and Swiss research bodies. His lab at IRB, established via the 2013 Marie Curie Career Integration Grant , develops novel imaging approaches and therapeutic strategies for infectious and immune-mediated diseases.

Joseph P. BresslerView profile

Associate Professor

• Neurotoxicology
• Environmental Health Sciences
• Metal Transporters
• +12 more

Joseph P. Bressler is an Associate Professor at Johns Hopkins University, jointly affiliated with the Bloomberg School of Public Health and the Krieger School of Arts and Sciences. He is a member of the Department of Environmental Health and Engineering and conducts research at the Kennedy Krieger Institute in Baltimore, Maryland. His work bridges public health, neuroscience, and molecular toxicology, focusing on environmental impacts on brain development. Education: PhD, Rutgers University, 1978 Dr. Bressler’s research centers on neurotoxicology, particularly how environmental pollutants such as lead, cadmium, and aluminum disrupt metal transport systems and affect neurodevelopment. His laboratory investigates the role of iron and other metal transporters at the blood-brain barrier and in glial cells, revealing mechanisms of metal uptake and toxicity. His work has implications for understanding autism, fetal alcohol syndrome, and other neurodevelopmental disorders. His recent publications highlight ongoing research into metal homeostasis, cytotoxicity in cancer and neuronal cell lines, e-cigarette aerosol variability, and epigenetic changes in sex chromosome aneuploidies. The research spans molecular mechanisms, in vitro models, and human health outcomes, demonstrating a multidisciplinary approach to environmental health. Scientific Contributions: Elucidated how lead and cadmium hijack iron transporters to enter the brain Demonstrated aluminum activation of iron uptake pathways in glial cells Investigated flavoring agents like ethyl maltol in enhancing metal toxicity Explored epigenetic and behavioral impacts in rare genetic conditions Dr. Bressler has advised numerous researchers and collaborators across disciplines. His work has been supported by federal and institutional grants, though specific funding details are not provided in the source text. He actively publishes in high-impact toxicology and environmental health journals, with research cited in policy and public health discussions. He leads a research laboratory focused on cellular and molecular mechanisms of neurotoxicity, utilizing in vitro models of the blood-brain barrier, astrocytes, and neuronal cell lines. His team collaborates widely across neuroscience, public health, and environmental engineering domains.

• Developmental Psychophysiology
• Temperament and Personality Development
• Neuroscience of Shyness and Social Anxiety
• +4 more

Professor Louis Schmidt is a leading academic in the Department of Psychology, Neuroscience & Behaviour at McMaster University , with a research focus on developmental psychophysiology, temperament, and the long-term effects of early adversity. His work bridges neuroscience, psychology, and behavioral science, emphasizing the interplay between brain function and socio-emotional development across the lifespan. Key research themes: Shyness, social anxiety, autism spectrum disorder, schizophrenia, and outcomes of extremely low birth weight. Recognized for mentoring postdoctoral fellow Kristie Poole, who was celebrated as a role model in the Child Emotion Laboratory. Scientific Awards : Royal Society of Canada recognition for contributions to research and scholarship. Research Trends from 15 recent publications include: Neurophysiological mechanisms of shyness (EEG, ERP, RSA) Impact of antenatal corticosteroids on adult brain function Intergenerational effects of maternal mental health interventions Cross-cultural comparisons of temperamental shyness Developmental consequences of preterm birth Behavioral and neural correlates of social anxiety in diverse populations Grants & Collaborations : Led the SNACS randomized controlled trial on antenatal corticosteroids, with applications in obstetrics and developmental neuroscience. Collaborates extensively on topics like autism spectrum disorder, schizophrenia, and emotion regulation. Labs & Teams : Directs the Child Emotion Laboratory at McMaster University, fostering interdisciplinary research on developmental psychopathology and neural mechanisms of temperament.

Donald RioView profile

Professor

• Nucleic Acid Transactions
• Transposable Elements
• RNA Binding Proteins
• +3 more

Donald Rio holds the Richard and Rhoda Goldman Distinguished Chair in the Biological Sciences and is a Professor of Biochemistry, Biophysics, and Structural Biology. He is affiliated with the Division of Biochemistry and Molecular Biology and the Center for Integrative Genetics. His lab focuses on nucleic acid transactions, including transposable element mobilization (P elements) and RNA binding protein mechanisms controlling alternative splicing. Research highlights include studies on THAP9 proteins in humans/zebrafish, cryo-EM structural analysis of transposase-DNA complexes, and splicing regulation in neurodegenerative diseases like ALS and Parkinson’s. His work combines biochemical, genetic, and computational approaches, including the development of the Junction Usage Model (JUM) for splicing analysis. Research interests span transposition mechanisms linked to HIV integration, immune system recombination, and evolutionary genome dynamics. His team investigates how RNA binding proteins like hnRNPA1 influence splicing in disease contexts, with projects involving CRISPR-based models and patient RNA-seq data analysis. Collaborations include studies on splicing accuracy across tissues and age, and the impact of splicing defects in neurodegenerative disorders. Key awards include the Goldman Chair. His lab’s contributions bridge fundamental molecular mechanisms with translational applications in genetic disease modeling and drug discovery. Recent work focuses on isogenic stem cell models (iSCORE-PD) for Parkinson’s research and structural biology insights into transposase function. Grants and projects involve NIH funding for ALS splicing studies and collaborations with institutions like the Buck Institute. His lab actively publishes in top journals such as Genome Research , PNAS , and Nature , with a strong emphasis on cryo-EM and bioinformatic methods.