Salvatore MazzeoView profile
Researcher
Salvatore Mazzeo is a fixed-term researcher (type B) in Neurology at Vita-Salute San Raffaele University, where he conducts research focused on early and atypical manifestations of dementia. His clinical work takes place at the Neurology Unit of IRCCS Policlinico San Donato. Dr. Mazzeo holds a PhD in Neuroscience from the University of Florence (2024) and is a specialist in Neurology from the same institution (2020). His research interests span dementia, Alzheimer's Disease, cognitive decline, neurodegenerative disorders, artificial intelligence applications in medicine, biomarkers, and genetics. His work particularly emphasizes the clinical, cognitive, genetic, and biological characteristics of early dementia manifestations, utilizing artificial intelligence techniques. His publication record reveals a strong focus on biomarkers (particularly neurofilament light chain), genetic factors (including HTT gene variations), and machine learning approaches for predicting cognitive decline progression. Dr. Mazzeo's recent publications show a clear trend toward integrating multiple biomarkers (plasma biomarkers, EEG, imaging) to develop prediction models for cognitive decline progression. His work bridges clinical neurology with advanced computational approaches, particularly in identifying early markers along the Alzheimer's Disease continuum from subjective cognitive decline to dementia. Junior Faculty Award - 18th International Conference on Alzheimer's & Parkinson's Diseases (2024) American Academy of Neurology's International Scholarship Award (2023) 2nd place winner, 'La ricerca in 3 minuti' Award (2021) Best poster, Italian Society for the Study of Dementias Congress (2020) Best poster, Winter seminar on Dementia and Neurodegenerative Disorders (2020) Best oral presentation, Winter seminar on Dementia and Neurodegenerative Disorders (2018) Dr. Mazzeo serves as an elected member of the Board of Directors for SINdem Tuscany section since 2021. His clinical work involves neurology and neurorehabilitation at major Italian hospitals, with teaching responsibilities in neurology and cognitive assessment for medical and rehabilitation students. His research combines clinical neurology with advanced computational approaches to identify early markers of cognitive decline progression.










