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Guoyao WuView profile

Professor

• Animal Nutrition
• Protein and Amino Acid Metabolism
• Nutritional Biochemistry
• +5 more

Guoyao Wu is a Distinguished Professor of Animal Nutrition at Texas A&M University's College of Agriculture & Life Sciences, holding dual appointments in the Department of Animal Science and the Graduate Faculty of Nutrition. His expertise spans nutritional biochemistry, protein metabolism, and reproductive physiology. Dr. Wu earned his B.Sc. from South China Agricultural University, M.Sc. degrees from Beijing Agricultural University and the University of Alberta, and a Ph.D. from the University of Alberta, followed by postdoctoral training at McGill University and Memorial University of Newfoundland. His research focuses on amino acid and protein metabolism across molecular, cellular, and whole-animal levels, using models like cattle, pigs, and aquatic species. Key areas include placental nutrient transport, fetal programming, and the role of amino acids in mitigating conditions like sarcopenia and intrauterine growth restriction. He has pioneered studies on glycine, creatine, and citrulline supplementation in livestock and aquaculture. Dr. Wu has received over 15 prestigious awards from China, Canada, and the U.S., including the Thousand-People-Talent Award and Changjiang Scholar Award. He serves on editorial boards of journals like Amino Acids and Frontiers in Bioscience , and teaches graduate courses in protein metabolism. His work bridges basic science and applied nutrition, with implications for improving livestock productivity, human health, and aquaculture sustainability. Current projects address amino acid requirements of companion animals, microgravity effects on metabolism, and placental biology in ruminants.

Massimo MischiView profile

Professor

• Biomedical Signal Processing
• Diagnostic Imaging
• Ultrasound Technology
• +4 more

Massimo Mischi is a Full Professor at the Faculty of Electrical Engineering of the Eindhoven University of Technology (TU/e) and chairs the Signal Processing Systems (SPS) Division , the largest division at TU/e with over 250 researchers. He founded the Biomedical Diagnostics (BM/d) Lab in 2012, which now includes 180 researchers and clinical/industrial advisors, focusing on biomedical signal processing for diagnostics and monitoring.

James LacefieldView profile

Professor

• Biomedical Ultrasound Imaging
• Vascular Imaging
• Cancer Research Applications
• +5 more

James Lacefield is a Professor in both the Department of Electrical and Computer Engineering and the Department of Medical Biophysics at Western University. He serves as Director of the School of Biomedical Engineering and maintains his research laboratory in the Amit Chakma Engineering Building. His academic appointments span multiple disciplines, reflecting the interdisciplinary nature of his work in biomedical ultrasound imaging. Dr. Lacefield earned his Ph.D. and B.S.E. in Biomedical Engineering from Duke University. His educational background established the foundation for his current research program that bridges engineering principles with medical applications. His research focuses on the physical acoustics and signal processing aspects of ultrasound imaging, with particular emphasis on quantitative vascular imaging applications. Dr. Lacefield's laboratory develops novel methods for color Doppler, power Doppler, and contrast-enhanced ultrasound imaging, with primary applications in cancer research. Current projects include optimization of high-resolution ultrasound systems for tumor vascular characterization and development of methods to quantify spatial blood flow distribution in tumors. Analysis of his recent publications reveals a strong focus on quantitative ultrasound techniques for cancer applications, with particular attention to tumor perfusion assessment using contrast-enhanced ultrasound. His work demonstrates increasing sophistication in speckle analysis methods to improve the reliability of perfusion measurements in preclinical tumor models. Associate Editor, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control Member, Council of Chairs of Bioengineering and Biomedical Engineering Member, College of Reviewers, Canadian Institutes of Health Research Dr. Lacefield maintains active collaborations with multiple research groups including the Imaging Research Laboratories at Robarts Research Institute. His professional activities include editorial work for major ultrasound journals and participation in national review panels for biomedical research funding.

Brendan A HarleyView profile

Professor

• Cell and Tissue Engineering
• Biomaterials
• Extracellular Matrix Analogs
• +3 more

Brendan A. Harley is the Robert W. Schaefer Professor in Chemical and Biomolecular Engineering at the University of Illinois at Urbana-Champaign (UIUC), with a joint appointment in the Carl R. Woese Institute for Genomic Biology. His research focuses on developing biomaterials to replicate complex tissue microenvironments, enabling insights into cell behavior during development, disease, and regeneration. He holds leadership roles in academic and professional organizations, including editorial positions for Science Advances and Tissue Engineering . Harley earned his SB from Harvard University (2000), SM/ScD from MIT (2002, 2006), and completed postdoctoral studies at Boston Children’s Hospital. **Education**: Sc.D., Massachusetts Institute of Technology, 2006 S.M., Massachusetts Institute of Technology, 2002 S.B., Harvard University, 2000 **Research Interests**: Engineering dynamic, spatially-patterned biomaterials to mimic extracellular matrices Regenerative repair of musculoskeletal tissues Biomaterial models of cancer microenvironments (e.g., glioblastoma) Artificial bone marrow systems for hematopoietic stem cell studies Harley’s work has produced over 100 peer-reviewed articles and co-authored a textbook Cellular Materials in Nature and Medicine . His lab develops materials for clinical applications, including osteochondral defect repair and craniofacial bone regeneration. Notable honors include the NSF CAREER Award (2013), AAAS Fellowship (2014), and AIMBE Fellowship (2019). **Awards/Recognition**: Fellow, AAAS (2014) Young Investigator Award, Society for Biomaterials (2014) Campus Distinguished Promotion Award, UIUC (2018) His research group emphasizes translational outcomes, with projects spanning biomaterial design, cancer modeling, and stem cell engineering. Collaborations include industry partners like Orthomimetics (acquired by TiGenix) and foundational studies on tumor microenvironments.

• Extracellular Vesicles
• Biomarker Discovery
• Exosome Biology
• +7 more

Carlos Salomon Gallo is a Professor and NHMRC Investigator Fellow (EL2) at The University of Queensland's Centre for Clinical Research, affiliated with the School of Biomedical Sciences. He directs the Centre for Extracellular Vesicle Nanomedicine and leads the Exosome Biology Laboratory. A globally recognized key opinion leader in extracellular vesicles (ranked 3rd worldwide by Expertscape), his research focuses on EV biology for diagnostic and therapeutic applications in ovarian cancer, gestational diabetes, preeclampsia, and other obstetrical syndromes. His research integrates proteomics (SWATH-MS), miRNA analysis, and advanced isolation techniques to develop liquid biopsies. Core interests include: EV biomarker discovery and validation for early disease detection. Mechanisms of EV-mediated signaling in metabolic and oncological pathologies. Engineering EVs for targeted drug delivery and CRISPR-Cas therapeutics. Clinical translation of EV-based diagnostics (IVDs) and therapeutics. Analysis of his recent articles reveals a dominant focus on EV profiling in pregnancy complications (gestational diabetes, preeclampsia) and oncology (ovarian cancer), utilizing multi-omics approaches. Key trends include developing high-sensitivity EV biosensors, understanding hypoxia-induced EV signaling, and exploring 3D models for EV research. He has received significant recognition, including: NHMRC Emerging Leadership Fellow NHMRC Investigator Fellow (EL2) He leads the Exosome Biology Laboratory and the UQ Centre for Extracellular Vesicle Nanomedicine, fostering cross-disciplinary collaboration. His work involves extensive national and international partnerships, evidenced by leadership roles in the Centre for Clinical Diagnostics and over 20 invited international talks in 5 years. He actively mentors HDR students and contributes to global EV research standards (MISEV2023).

• Gynecologic Oncology
• Cancer Immunotherapy
• Tumor Immunology
• +7 more

Dr. Alessandro D. Santin is a Professor at the Yale School of Medicine within the Department of Obstetrics, Gynecology & Reproductive Sciences . He serves as Clinical Research Team Leader for Gynecologic Oncology at the Yale Cancer Center and co-chief of the Section of Gynecologic Oncology. Graduated magna cum laude from the University of Brescia, Italy Completed fellowships at the University of California, Irvine and University of Arkansas for Medical Sciences Dr. Santin's research bridges tumor immunology and translational oncology, focusing on: Immunotherapy for chemotherapy-resistant gynecologic cancers Therapeutic HPV vaccines for genital tumors Monoclonal antibody development Angiogenesis and radiation biology His recent publications highlight advancements in: VEGF/VEGFR2 system targeting for ovarian cancer Personalized medicine approaches with biomarkers Microsatellite instability in endometrial cancer immunotherapy Antibody-drug conjugates for uterine serous carcinoma NAC supplementation in post-COVID gynecologic patients Scientific Awards: American Association young investigator award Italian Society of Gynecologic Oncologists award for translational science Dr. Santin's lab (Laboratory for Surgery, Obstetrics & Gynecology) at Yale collaborates extensively, with 50+ postdoctoral fellows mentored. Current grants include NIH funding for Clostridium Perfringens Enterotoxin as a novel ovarian cancer therapy and leadership in multiple Gynecologic Oncology Group trials.

Andrew GodwinView profile

Professor

• Molecular Oncology
• Precision Medicine
• Biomarker Discovery
• +3 more

Andrew Godwin is a Professor at the University of Kansas Medical Center , where he serves as the Chancellor’s Distinguished Chair in Biomedical Sciences and Director of Molecular Oncology in the Department of Pathology and Laboratory Medicine. He is also the Deputy Director of the NCI-designated University of Kansas Cancer Center and the Founding Director of the Kansas Institute for Precision Medicine and Biospecimen Shared Resource . Dr. Godwin is a leader in translational research and precision medicine , with a focus on molecular oncology , biomarker discovery , and genomic diagnostics . His work bridges basic and clinical science to improve cancer patient care, particularly in ovarian cancer , Ewing sarcoma , and breast cancer . He has contributed over 230 ovarian cancer-related publications and pioneered studies linking the PI3K/AKT pathway to cancer treatment targets. His research program encompasses liquid biopsies using extracellular vesicles , molecular therapeutics , companion diagnostics , and clinical trial validation . He leads the Biomarker Discovery Laboratory and has secured over $250M in extramural funding , including a $11.4M NIH grant for precision medicine initiatives. His team has developed CELLSEARCH® , the first FDA-cleared test for circulating tumor cells. Notable awards include the Dolph C. Simons, Sr. Higuchi Award (2020), Outstanding Mentorship in Pathology Award (2024), and multiple mentoring accolades from KU. He has mentored over 150 trainees across career stages and leads a multidisciplinary lab with expertise in genomics , proteomics , and bioengineering . Academic Roles: Chancellor’s Distinguished Chair in Biomedical Sciences Director, Molecular Oncology, Pathology and Laboratory Medicine Deputy Director, KU Cancer Center Founding Director, Kansas Institute for Precision Medicine Adjunct Professor, Bioengineering Program, University of Kansas Scientific Awards: KUMC Achievement Award for mentoring postdocs (2014) Chancellor’s Club Award for Research (2018) Dolph C. Simons, Sr. Higuchi Award (2020) KU Excellence in Mentoring Award (2021) Outstanding Mentorship in Pathology (2024) Key Research Themes: Extracellular vesicles as liquid biopsy tools Molecular mechanisms of sarcoma and breast cancer Genomic diagnostics and precision oncology Clinical trial biomarker validation Biospecimen repository leadership

Anders BacklundView profile

Professor

• Pharmacognosy
• Natural Products Chemistry
• Chemical Space Navigation
• +4 more

Anders Backlund is Professor of Pharmacognosy at Uppsala University's Department of Pharmaceutical Biosciences, with dual institutional roles including Garden Director at Uppsala Linnaean Gardens. His work bridges pharmaceutical sciences and botanical heritage through the university's historic gardens. His research centers on pharmacognosy and natural products chemistry, with pioneering development of the ChemGPS-NP platform for chemical space navigation. This computational tool maps biological activity in chemical property space, enabling prediction of pharmacological effects and mechanisms of action. His work spans plant metabolomics, evolutionary chemography, and drug discovery from natural sources including marine organisms, fungi, and medicinal plants. Recent publications (2019-2023) demonstrate strong continuity in applying ChemGPS-NP to diverse problems: predicting membrane permeability of Alpinia galanga constituents (2022), evaluating Ononis isoflavonoids for CNS targeting (2022), and decoding multi-functional bioactivities in Maca (2021). His work increasingly integrates computational prediction with experimental validation across anti-inflammatory, anti-allergic, and antimicrobial domains. As Garden Director of Uppsala Linnaean Gardens, he maintains institutional connections to botanical heritage while advancing modern pharmacognosy. His dual roles exemplify the integration of historical plant knowledge with contemporary drug discovery methodologies.

• Reproductive Biology
• Placental Development
• Developmental Origins of Health and Disease (DOHaD)
• +4 more

Jayne Charnock is a Senior Lecturer in Biomedical Science at Edge Hill University, specializing in reproductive biology with a focus on implantation, placental development, and the Developmental Origins of Health and Disease (DOHaD). Her career spans research in placental vascular development, wound healing, and maternal-fetal health, alongside teaching roles in pathology, anatomy, and pharmacology. Education: BSc (Hons) in Anatomical Sciences PhD from University of Manchester (cytotrophoblast research with Professors John Aplin and Melissa Westwood) Jayne’s research explores placental blood vessel formation, placental stem cells, regulators of implantation, pregnancy in polycystic ovary syndrome (PCOS), and prenatal programming. Her work emphasizes in vitro models of cell function and translational applications for fetal growth restriction and maternal health. Recent publications highlight her expertise in placental vasculogenesis, PCOS effects on embryo implantation, and prolactin transcription dynamics. Collaborative projects address dietary impacts on recurrent miscarriage and trophoblast-stem cell interactions. Jayne mentors Final Year Project students and engages in public science outreach, including STEM Ambassador roles and partnerships with local schools and the Scout Association.

David NataleView profile

Associate Professor

• Cell Biology
• Regenerative Medicine
• Stem Cell Biology
• +4 more

Dr. David Natale is an Associate Professor in the Department of Obstetrics and Gynaecology at Queen's University, with a cross-appointment in the Department of Biomedical and Molecular Sciences. His research focuses on placental development, particularly in pregnancies complicated by maternal disease (e.g., pre-eclampsia, diabetes) or exposures (e.g., cannabis). He uses mouse and rat models to study trophoblast stem cell differentiation and placental dysfunction. Education: Ph.D. in Physiology and Pharmacology (University of Western Ontario, 2003), B.Sc. (University of Western Ontario, 1996). Postdoctoral training under Dr. Jay Cross (University of Calgary) and later appointments include Assistant Professor roles at the University of Calgary (2008–2013) and University of California San Diego (2013–2019). Research interests span cell biology, regenerative medicine, and placental biology. His lab investigates how trophoblast populations and interactions are altered under compromised conditions, with recent emphasis on cannabinoid effects and maternal-fetal outcomes. Grants and funding include support from CIHR, NIH/NICHD, and UCSD/UCLA Diabetes Research Center. Current supervision includes postdoctoral fellow Samantha Benton. Labs/Teams: Queen's University placental research group, collaborations with human placenta research teams.

• Obstetrics
• Gynecology
• Placenta Diseases
• +5 more

Dr. Seth Guller is a Senior Research Scientist and Director of the Gyn/Endocrine Laboratory at the Yale School of Medicine. He specializes in reproductive sciences, focusing on placenta diseases, pre-eclampsia, and pregnancy outcomes. His research integrates biochemistry and clinical laboratory techniques to improve patient care, particularly through advanced hormone analysis using the Roche Cobas e411 analyzer. Dr. Guller holds a PhD from Mount Sinai School of Medicine (1986) and has authored over 75 peer-reviewed publications. Affiliations: Yale Fertility Center, Reproductive Endocrinology & Infertility Division, Perinatal Research Group Key Research Areas: Placental biology, maternal-fetal immune interactions, viral infections in pregnancy, and cytokine regulation in reproductive health. His laboratory has pioneered studies on mechanisms underlying preeclampsia, Zika virus vertical transmission, and the impact of maternal obesity on placental function. Collaborations with clinicians like Dr. Charles Lockwood and Dr. Harvey Kliman highlight translational research bridging basic science and clinical care. Recent publications (2020–2023) emphasize placental immunology, SARS-CoV-2 effects on pregnancy, and metabolic pathways influencing fetal development. His work has advanced understanding of Hofbauer cell functions, cytokine signaling, and viral pathogenesis in obstetrical contexts.

Orestis L. KatsamenisView profile

Lecturer

• 3D X-ray Histology
• Microfocus Computed Tomography
• Biomedical Imaging
• +6 more

Dr Orestis L. Katsamenis is a Lecturer in Biomedical Imaging at the University of Southampton , affiliated with the Faculty of Engineering and Physical Sciences (FEPS) and the Faculty of Medicine (FoM) . He leads the 3D X-ray Histology and Biomedical Imaging Theme at the μ-VIS X-ray Imaging Centre and holds a visiting position at the University Hospital Southampton NHS Foundation Trust in the Biomedical Imaging Unit of Cellular Pathology and Child Health. Education: BSc in Materials Science (University of Patras, 2007), MSc in Materials Science (University of Patras, 2009), PhD in Bioengineering (University of Southampton, 2012). His research focuses on 3D X-ray Histology (XRH) and Microfocus Computed Tomography (μCT) applied to biological and clinical imaging , pharmaceutical technology , and bone nanostructure . He has pioneered μCT protocols for clinical histology and developed advanced 3D imaging tools for applications in drug delivery , tissue engineering , and evolutionary biology . His work spans multidisciplinary collaborations with engineers, medical professionals, and paleontologists. Recent publications highlight his contributions to 3D imaging of bone , microneedle design , 4D-printed polypills , and paleontological studies . He has received awards including the EPSRC Doctoral Prize Award (2012) and multiple scientific presentation honors (2018) . Dr Katsamenis supervises PhD student Ayesha Mohiud Din and collaborates with research groups like the Engineering Materials and Surface Engineering Group and the Institute for Life Sciences . His Google Scholar profile lists over 20 recent articles, showing his prolific and diverse research output.

• Signal Regulated Transcription
• Chromatin and Gene Regulation
• Nuclear Receptors
• +7 more

W. Lee Kraus is a Professor and Director at the Cecil H. and Ida Green Center for Reproductive Biology Sciences at UT Southwestern Medical Center, where he also holds leadership roles including Vice Chair for Basic Sciences in the Department of Obstetrics and Gynecology, Assistant Director for Basic Research at the Simmons Comprehensive Cancer Center, and Assistant Dean for Research Development. He is also a member of the Board of Directors of the Endocrine Society (2023–2026). Ph.D., University of Illinois at Urbana-Champaign (1994) Postdoctoral Research, University of California, San Diego B.S., Cornell University (1989) Dr. Kraus's research centers on signal-regulated transcription, chromatin and gene regulation, nuclear receptors, PARPs, and NAD+ metabolism and signaling. His work has elucidated the roles of ADP-ribosylation in transcriptional control, enhancer function, and cancer biology. He has published over 150 peer-reviewed articles in top journals such as Science , Cell , and Molecular Cell . His recent publications reveal a strong focus on PARP enzymes, enhancer RNAs, NAD+ compartmentalization, and the interplay between metabolism and gene regulation. Themes across his work include the functional roles of ADP-ribosylation in transcription, splicing, translation, and cancer, with implications for therapeutic development. Scientific honors include: Endocrine Society’s Richard E. Weitzman Memorial Award (2007) Endocrine Society’s Ernst Oppenheimer Award (2014) Cornell University Teaching Excellence Award (2004) Cornell University Mentoring Excellence Award (2008) Dr. Kraus has been a successful mentor, training 22 doctoral students, 26 postdocs, and 16 clinical fellows, most of whom have secured faculty or research positions in academia or industry. His research has been supported by grants from the NIH, American Cancer Society, Burroughs Wellcome Fund, CPRIT, and NSF. He is also active in biotech, having co-founded Ribon Therapeutics and ARase Therapeutics, and serves on scientific advisory boards for startup companies. He leads the Kraus Lab at UT Southwestern, which continues to pioneer research in transcriptional regulation and metabolic signaling.

Phillip D. ZamoreView profile

Professor

• RNA Interference
• Small RNA Biology
• piRNA Pathways
• +3 more

Phillip D. Zamore serves as Chair and Professor of the RNA Therapeutics Institute at the University of Massachusetts Chan Medical School School of Medicine and is an Investigator of the Howard Hughes Medical Institute. He holds the Gretchen Stone Cook Professorship in Biomedical Sciences and leads pioneering research in RNA biology. Dr. Zamore earned his A.B. (1986) and Ph.D. (1992) in Biochemistry and Molecular Biology from Harvard University, followed by postdoctoral training at The Whitehead Institute for Biomedical Research. His research focuses on small RNA silencing pathways including RNA interference (RNAi), microRNA, and PIWI-interacting RNA (piRNA) mechanisms across eukaryotic and prokaryotic systems. Key investigations explore how Argonaute proteins achieve sequence-specific regulation of transcription and translation, with emphasis on piRNA biogenesis in germ cells and bacterial Argonaute functions. Analysis of his recent publications reveals dominant themes in transposon silencing, piRNA pathway evolution, RNA therapeutic development, and molecular mechanisms of gene regulation. His work bridges fundamental biochemistry with clinical applications, particularly in RNA-based therapies for genetic disorders. Notable scientific honors include: Chancellor’s Medal for Excellence in Scholarship (2015) Dean's Award for Research Mentoring (2011) Fellow of the National Academy of Inventors (2014) Election to the American Academy of Arts & Sciences, National Academy of Sciences, and National Academy of Medicine (2023) Dr. Zamore has co-founded multiple biotechnology companies including Alnylam Pharmaceuticals (2002), which developed the FDA-approved RNAi therapeutic ONPATTRO for hereditary transthyretin-mediated amyloidosis, and Voyager Therapeutics (2014). His laboratory has trained dozens of researchers now leading institutions worldwide, with over 150 publications and 119 patents reflecting his translational impact. Current research leverages biochemical and genetic approaches to develop RNA-guided therapies for diseases like Huntington's. The Zamore Laboratory operates within the RNA Therapeutics Institute at UMass Chan Medical School, utilizing advanced genomic, biochemical, and imaging technologies to study small RNA pathways in model organisms including Drosophila, mice, and bacterial systems.

Milan K. BagchiView profile

Professor

• Endocrinology
• Reproductive Biology
• Signal Transduction
• +4 more

Milan K. Bagchi is the Deborah Paul Professor of Molecular & Cellular Biology and Director of the School of Molecular & Cellular Biology at the University of Illinois Urbana-Champaign. He also holds a joint appointment as Professor of Molecular & Integrative Physiology. His research focuses on steroid hormone signaling mechanisms in reproduction and disease, particularly estrogen and progesterone regulation of embryo implantation and cancer biology. Education: B.S. (1976), M.S. (1979) from University of Calcutta, India; Ph.D. (1984) from University of Nebraska; Postdoc (1985–89) at Baylor College of Medicine. Research interests include endocrinology, reproductive biology, and signal transduction. Key areas: hormonal regulation of implantation, gene networks in fertility, and molecular basis of hormone-dependent cancers. His lab uses mouse models and genomic approaches to study uterine function and hormonal pathways. Notable awards: Romano Professorial Scholar and University Scholar. Recent work highlights include studies on phthalate impacts on uterine physiology (2023), hypoxia-driven embryo implantation mechanisms (2025), and decidualization pathways. His publications span hormone signaling, environmental toxin effects, and cell communication in reproductive systems. Awards and honors include roles as a distinguished scholar and contributions to biomedical research. Collaborations extend to institutions like the Carle Illinois College of Medicine and the Carl R. Woese Institute of Genomic Biology.