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Salvador Borrós GómezView profile

Professor

• Materials Science
• Biomaterials
• Polymer Engineering
• +16 more

Salvador Borrós Gómez is a Full Professor and Director General at IQS School of Engineering, Universitat Ramon Llull, where he is affiliated with the Department of Chemical Engineering and Materials Science and the Bioengineering Department. He leads the GEMAT (Materials Engineering Group), a recognized research group in materials science and nanomedicine. His work bridges academic leadership, research innovation, and industrial collaboration. PhD in Chemical Engineering, IQS (1993) Bachelor in Materials Characterization, Universitat de Barcelona (1993) MBA, IQS (1993) Bachelor in Chemical Engineering, IQS (1987) His research focuses on functional polymeric materials , biomaterials , and nano-drug delivery systems , with applications in tissue engineering, cancer therapy, and sustainable materials. He has pioneered work in stimuli-responsive nanoparticles, smart surfaces, and 3D bioprinting of soft biomaterials. His research lines include the design of biomimetic surfaces, high-performance adhesives, and materials for fuel cells and rapid manufacturing. The most recent articles highlight a strong trend in nanomedicine , particularly in mRNA and siRNA delivery for cancer and genetic diseases, 3D printing of silicone-based soft materials , and advanced hydrogel systems for localized therapy. There is also significant work on pregnancy-safe nanotherapies and biomedical device innovation , reflecting a translational focus from lab to clinic. He has received no explicitly listed scientific awards in the provided texts, but his leadership in major research grants and high-impact publications suggests national and international recognition. Borrós has supervised multiple PhD students and research projects, including FPI fellowships and industrial collaborations. He has led or co-led major research initiatives such as 3D-CARTIBONE, RECYVAL, COVINANOVAX, and CERTERA, which involve interdisciplinary teams and significant external funding. His work emphasizes technology transfer and real-world impact. He leads the GEMAT research group, which is part of the TecnoCampus Maresme and affiliated with ACCIÓ’s Tecnio network. The group focuses on three pillars: new functional materials, surface engineering, and biomaterials. It is a fully consolidated research group (SGR) recognized by AGAUR and actively involved in both academic and industrial innovation.

Neville SanjanaView profile

Associate Professor

• Genome Engineering
• Neuroscience
• Cancer Research
• +4 more

Neville Sanjana is an Associate Professor at the Department of Neuroscience , NYU Grossman School of Medicine , with a joint affiliation at the New York Genome Center . His academic journey began with a PhD at Massachusetts Institute of Technology . Research Interests in genome engineering, CRISPR technology, and functional genomics focus on: Dissecting noncoding genomic elements across cancers Developing high-throughput CRISPR screening methods Engineering therapies for neurological and genetic diseases Understanding transcriptional regulation in neuronal differentiation Recent Articles span cancer genomics, synthetic biology, and CRISPR-based diagnostics, with a thematic emphasis on: Drug resistance mechanisms in melanoma Noncoding element function in disease Advancements in base and prime editing Applications in immunotherapy and hemoglobin disorders Scientific Honors : NIH Director's New Innovator Award Sidney Kimmel Scholars Program DARPA Young Faculty Award Simons Foundation Autism Research Initiative Melanoma Research Alliance Young Investigator Award Teaching : In Spring 2022, he taught Special Topics: Genome Engineering (BIOL-UA 920) at NYU Biology, covering CRISPR evolution, gene therapies, and ethical implications of genome editing. Lab Operations : The Sanjana Lab operates from two locations - NY Genome Center (101 Avenue of the Americas, 4th floor, New York, NY 10013) and NYU Biology (755 Brown, 100 Washington Sq East, New York, NY 10003).

Alfredo BensoView profile

Professor

• Bioinformatics
• Systems Biology
• Artificial Intelligence
• +16 more

Alfredo Benso is a Full Professor in the Department of Control and Computer Science (DAUIN) at the Polytechnic University of Turin, where he is also a member of the Interdepartmental Center PolitoBIOMed Lab - Biomedical Engineering Lab. He has been continuously involved in the Doctoral College for Computer and Systems Engineering since 2008, guiding PhD education across numerous cycles. His academic roles span teaching and research leadership in bioinformatics, systems biology, and computer engineering. Research interests: Bioinformatics and computational biology Systems biology and gene regulatory networks Artificial intelligence and machine learning in biomedicine Molecular modeling and multiscale simulation Biological database systems and data integration Health informatics and public health modeling His recent publications reflect a strong trend in applying AI and machine learning to biological and medical challenges, including protein function prediction, Alzheimer’s and Multiple Sclerosis modeling, food fraud detection, and viral genome analysis. These works span journals and conferences in bioinformatics, computational biology, and biomedical engineering, demonstrating interdisciplinary innovation. Scientific Awards: BIOINFORMATICS 2014 BEST PAPER AWARD (INSTICC, United Kingdom) Advising and Grants: He supervises PhD students, including Sofia Ostellino, and leads major research initiatives such as the BIGMECH (2023–2025) and FISHUB (2016–2018) projects. He has served as Scientific Director for collaborative agreements with public administrations and as Principal Investigator on EU, national (PRIN), and regional research grants focused on bioinformatics, space systems, and reliable digital technologies. Labs and Teams: He is a key member of the SBG - System Biology Group (DAUIN) and contributes to PolitoBIOMed Lab, fostering collaborative research in biomedical engineering and computational biology.

Younbok LeeView profile

Senior Lecturer

• Gene Therapy
• Neurodegenerative Diseases
• Neuroscience
• +3 more

Dr. Younbok Lee is a Senior Lecturer in Basic and Clinical Neuroscience at King's College London. He is also Vice President and Head of Discovery at AviadoBio, a university spin-out专注于基因治疗开发 for neurodegenerative disorders. His primary research focuses on gene therapy strategies for amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), particularly targeting C9orf72 mutations and RNA-binding proteins like TDP-43. He collaborates closely with institutions like University College London and the Motor Neurone Disease Association. His work integrates molecular biology, gene therapy vectors, and preclinical studies to address challenges in neurodegenerative disease treatment. Key collaborations include projects with Professors Christopher Shaw and James Uney. Dr. Lee leads multiple funded initiatives, including AAV gene therapy trials and industry partnerships to advance therapies for debilitating neurological conditions. Notable projects include the development of AVB-101 (a gene therapy targeting frontotemporal dementia) and studies on ER-mitochondria interactions in neurodegeneration. His publications emphasize mechanisms of RNA misprocessing, dipeptide repeat proteins, and cellular stress responses in ALS/FTD progression.

John V. BrigandeView profile

Associate Professor

• Neuroscience
• Developmental Biology
• Auditory Development
• +4 more

John V. Brigande is an Associate Professor at the Oregon Hearing Research Center, Oregon Health & Science University. He began his academic career at Boston College where he earned his B.S. (1987), M.S. (1991), and Ph.D. (1997) in neuroscience and developmental neurobiology. His postdoctoral training included developmental genetics at the University of Texas at Austin (1998) and auditory development at Purdue University (2003). He joined the Oregon Hearing Research Center as an Assistant Professor in 2003 and was promoted to Associate Professor in 2009. Since 2011, he has been a key contributor to the Hearing Health Foundation's Hearing Restoration Project. Education: B.S., Boston College, 1987 M.S., Boston College, 1991 Ph.D., Boston College, 1997 Postdoctoral Fellowship, University of Texas at Austin, 1998 Postdoctoral Fellowship, Purdue University, 2003 Brigande's research focuses on mammalian inner ear development , employing experimental embryology, surgical techniques, and gene transfer methods to study developmental processes in vivo. His lab investigates cell fate decisions in otic progenitors using retroviral lineage analysis and develops fetal gene/drug therapies for congenital deafness. A major focus is translating developmental mechanisms into gene and cell therapies for hearing loss and balance disorders, with particular emphasis on hair cell regeneration strategies. His publications demonstrate a strong focus on translational approaches to hearing restoration , including gene therapy (CRISPR/Cas9, AAV vectors), antisense oligonucleotides for congenital disorders, and optimization of diagnostic techniques. Recent work explores primate models of Usher syndrome, fetal pharmacotherapy, and mitochondrial genetics, reflecting interdisciplinary collaboration across genetics, audiology, and developmental biology. Brigande leads a research laboratory within the Hearing Health Foundation's Hearing Restoration Project consortium, focused on developing mouse model systems to validate hair cell regeneration candidates. The lab utilizes techniques including transuterine microinjection, in vivo electroporation, and single-cell transcriptomics to advance therapeutic strategies for inner ear disorders.

• Cancer
• Cell Biology
• Genetics
• +3 more

Dr. Charles Bailey is a Senior Research Fellow at the University of Sydney's Central Clinical School, Department of Medicine, and an affiliated researcher at the Centenary Institute of Cancer Medicine & Cell Biology. His work focuses on cancer biology, epigenetics, and molecular mechanisms underlying genetic diseases. Dr. Bailey leads projects investigating CTCF protein functions in cancer, alternative splicing regulation, and therapeutic targeting of cancer-related pathways. Research Interests: Dr. Bailey's research spans cancer epigenetics (particularly CTCF and chromatin remodeling), gene therapy development, protein-protein interaction networks, and molecular mechanisms of tumor suppression. His work combines experimental models (mouse and cell cultures) with clinical data analysis to bridge basic science and translational medicine. Recent Directions: His articles from 2023 highlight clinical trials for novel cancer drug combinations (e.g., olaparib/durvalumab) and mechanisms of embryo development. Earlier work revealed critical roles for CTCF in genome regulation, while 2022 studies advanced understanding of NuRD complex interactions and lens development pathways. Grants & Awards: Recipient of multiple grants including Tour de Cure's Pioneering Research Awards (2023, 2022, 2021) and Cancer Council NSW support. Projects focus on exploiting genomic vulnerabilities in pancreatic/endometrial cancers and developing gene therapy delivery systems. Collaborations: Active collaborations across Sydney's medical research community, including work with Prof. John Rasko on gene therapy vectors and Prof. Michelle Semsarian on heart disease mechanisms.

David R. DeyleView profile

Associate Professor

• Gene Therapy
• Cell Therapy
• Genomic Editing
• +12 more

David R. Deyle, M.D., is an Associate Professor of Medical Genetics at Mayo Clinic in Rochester, Minnesota. He holds primary and joint appointments as a Consultant in the Department of Medical Genetics, Department of Molecular Medicine, Department of Cardiovascular Medicine, Department of Orthopedic Surgery, and Department of Pediatric and Adolescent Medicine. His multidisciplinary role reflects his integrative research in gene and cell therapy for genetic disorders. Dr. Deyle earned his M.D. from the University of Minnesota Medical School, completed residency in Internal Medicine and Pediatrics at the University of Minnesota, and underwent fellowship training in Medical Genetics at the University of Washington, Seattle. He is board-certified in Clinical Genetics and Genomics by the American Board of Medical Genetics and Genomics. His research focuses on developing gene and cell therapies through genomic editing in human stem cells. Key areas include treating osteogenesis imperfecta using iPSCs and AAV vectors, in vivo modeling of skeletal diseases, and oncolytic measles virus (MV-NIS) therapy for neurofibromatosis 1 (NF1) tumors. His work leverages CRISPR, TALENs, and adeno-associated virus (AAV) technologies to precisely modify the genome in mesenchymal and induced pluripotent stem cells for regenerative medicine applications. Analysis of his recent publications reveals a strong trend in clinical genomics, stem cell engineering, and translational gene therapy. His work spans rare genetic disorders such as Ehlers-Danlos syndrome, achondroplasia, and mucopolysaccharidosis, with a consistent emphasis on improving diagnostic and therapeutic pipelines through genomic innovation. Discovery Science Award, Regenerative Medicine Minnesota (2020–2022) Gene Therapy of Arthritis and Related Disorders Young Investigator Award (2008) NIH Loan Repayment Program Grant (2006) Summa Cum Laude, University of Minnesota (1993) Dr. Deyle has served as Principal Investigator on multiple NIH-funded grants, including projects on in vivo gene targeting for inherited bone disease and engineering pluripotent stem cells for osteogenesis imperfecta. He has also been a mentor and committee member in the American Society of Gene & Cell Therapy and has reviewed grants for NIH study sections (NIAMS, NINDS, NCMRR). His laboratory is part of the Center for Individualized Medicine and the Center for Regenerative Biotherapeutics at Mayo Clinic, where his team develops preclinical models and novel viral vector systems for genetic correction.

Bruno CorreiaView profile

Associate Professor

• Protein engineering
• Computational design
• Immunoengineering
• +7 more

Bruno Correia is an Associate Professor at the Laboratory of Protein Design & Immunoengineering (LPDI) within the Institute of Bioengineering at École Polytechnique Fédérale de Lausanne (EPFL) , Switzerland. His work bridges computational protein design with experimental validation, focusing on immunoengineering applications for vaccines and cancer immunotherapy. PhD in Computational Biology (Universidade Nova de Lisboa, 2010) BSc in Chemistry (Universidade de Coimbra, 2004) Correia's research spans protein engineering , synthetic biology , and computational design , with key contributions in: Developing MaSIF for protein surface interaction analysis Designing chemically-controlled protein switches for CAR T-cell therapy Creating de novo functional proteins for vaccine development His publications highlight vaccinology , structural bioinformatics , and machine learning applications in protein science. Awards include the Protein Society Young Investigator Award (2021) and ERC Starting Grant (2016) . Scientific contributions: Protein surface fingerprinting for interaction prediction Rational immunogen design for HIV and hepatitis C Deep learning frameworks for protein structure generation

Stefano MenegattiView profile

Associate Professor

• Biomanufacturing
• Peptide-based affinity ligands
• Biopharmaceutical purification
• +5 more

Stefano Menegatti is an Associate Professor and University Faculty Scholar in the Department of Chemical and Biomolecular Engineering at North Carolina State University (NC State). His research focuses on developing peptide-based technologies for biopharmaceutical purification, drug delivery systems, and advanced biomaterials. He holds a Ph.D. in Chemical Engineering from NC State (2013), and M.Sc. and B.Sc. degrees from the Università di Bologna (Italy). Menegatti’s work emphasizes stimuli-responsive peptide ligands for purifying labile biologics like stem cells and therapeutic proteins, as well as hydrogel systems for controlled drug release. His lab also develops transdermal delivery platforms for vaccines and explores biodegradable polymers for medical devices. He leads the Ligand Design & Biomanufacturing Group within the College of Engineering. Education: Ph.D., Chemical Engineering, NC State (2013) M.Sc., Chemical Engineering, Università di Bologna (2008) B.Sc., Chemical Engineering, Università di Bologna (2006) His research interests span biomanufacturing , viral vector purification , host-cell protein removal , and biodegradable materials . Recent advancements include adaptive machine learning frameworks for viral vector production and shear-responsive nanocoatings for biomedical applications. Awards: ACS BIOT Young Investigator Award (2025) NSF CAREER Award (2017) NCSU Chancellor’s Innovation Fund (2019) Menegatti collaborates with industry partners on process analytical technologies (PAT) and has pioneered peptide ligand systems for AAV, lentivirus, and adenovirus purification. His lab actively explores sustainable biomanufacturing strategies, including engineered microbes for PET plastic degradation.

• Vision Science
• Retinal Neurons
• Synaptic Trafficking
• +5 more

Melina Agosto is an Assistant Professor in the Departments of Physiology and Biophysics and Ophthalmology & Visual Sciences at Dalhousie University, Faculty of Medicine. Her research focuses on retinal synapse biology, specifically proteins involved in synapse formation and function. She holds a BS from MIT, a PhD from Harvard, and postdoctoral training at Boston Children’s Hospital and Baylor College of Medicine. Education: BS, Massachusetts Institute of Technology PhD, Harvard University Postdoctoral Fellow, Boston Children’s Hospital Postdoctoral Fellow, Baylor College of Medicine Research interests include: Retinal neuron signaling Membrane protein trafficking Glutamate receptor function Protein-protein interactions in synapses Her work employs biochemical experiments and in vivo models to study synaptic development and dysfunction. Key research themes from recent articles include: Role of mGluR6 glycosylation in trans-synaptic interactions Cryo-EM analysis of photoreceptor ciliary structures Super-resolution microscopy of rhodopsin trafficking Vps34 kinase regulation in retinal cells Her studies bridge biochemistry, structural biology, and neurobiology to advance understanding of retinal disease mechanisms.

• Gene Therapy
• Fetal Medicine
• Medical Biotechnology
• +5 more

Simon Waddington is a Professor of Gene Therapy at the University College London (UCL) within the Ega Institute for Women's Health and Faculty of Population Health Sciences . His work bridges gene therapy , maternal-fetal medicine , and genetic disorder research . Research interests focus on translational gene therapy for childhood inherited diseases , particularly neurodegenerative disorders , metabolic conditions , and lysosomal storage diseases . Key areas include viral vector engineering (AAV, lentivirus), placental-targeted therapies , and mitochondrial dysfunction interventions. His 150+ peer-reviewed publications grants exceeding £20M patent filings (x8) highlight achievements in journals like Nature , Science Translational Medicine , and Blood . Articles reveal trends in AAV-mediated gene delivery , preterm birth models , and multi-organ disease targeting . Collaborations span European Research Council , Medical Research Council , LifeArc , and institutions in Singapore, South Africa, and across Europe. He chairs UCL's Cell and Gene Therapy Therapeutic Innovation Network and co-founded Bloomsbury Genetic Therapies .

Weishan HuangView profile

Associate Professor

• Immunology
• Regulatory Immunity
• Immune Memory
• +9 more

Weishan Huang is an Associate Professor of Immunology in the Department of Pathobiological Sciences at the LSU School of Veterinary Medicine, Louisiana State University. She joined the LSU Vet Med Faculty on January 3, 2018, and leads the Huang Lab which focuses on immune system research. Dr. Huang earned her PhD from Cornell University (2014), MS from Pennsylvania State University (2010), and BS/BE from Tsinghua University in China (2008). Her research spans immunology, regulatory immunity, immune memory, vaccination, infectious diseases, and cancer immunology with a focus on T cell signal transduction in host defense and immunopathology. Her laboratory investigates regulatory T cell development and function, memory and homeostasis of CD8+ T cells, and antiviral/immune modulating drug discovery. She utilizes disease models including influenza infection, COVID-19, allergic asthma, cancer, and colitis to study immune homeostasis and develop immunotherapies like immune checkpoint blockades and CAR-T therapy. Dr. Huang serves as course coordinator and lecturer for Veterinary Immunology (VMED 5172) and Basic Immunology (PBS 7003), and lectures on virology topics related to Orthomyxoviridae and Retroviridae. Her recent publications demonstrate expertise in T cell signaling, viral immunology, and immunotherapeutic approaches to disease. AAI ASPIRE Award (2024) COBRE Rising Star Award (2024) LSU Vet Med Distinguished Scholar Award (2023) LSU Alumni Association Rising Faculty Research Award (2022) Zoetis Award for Veterinary Research Excellence (2021) Dr. Huang mentors students including Michael McGee, who received the LSU Vet Med Distinguished Dissertation Award in 2023. She has secured significant grant funding as Principal Investigator from NIH, Hevolution/AFAR, and other sources for projects on immune memory, ITK signaling, and viral infection. As a Standing Member of the NIH Study Section for Immunity and Host Defense and Associate Editor for Journal of Medical Virology and Frontiers in Immunology, she plays an active role in the scientific community. The Huang Lab, composed of biologists, statisticians, mathematicians, and artists, aims to understand how the mammalian immune system balances effector and regulatory immune responses to develop innovative strategies for disease prevention, diagnosis, and treatment.

• Telomere Biology
• Cancer Genetics
• Genomic Stability
• +3 more

Professor Hilda Pickett is Head of the Telomere Length Regulation Unit at the Children's Medical Research Institute (CMRI) and holds a conjoint professorship at the University of Sydney. Her research focuses on telomere biology, particularly the molecular mechanisms of telomere length control, genomic stability, and cellular immortality in cancer. PhD, University of Leicester, UK Postdoctoral experience: Cancer Research UK (Leeds) and CMRI, Australia Research Highlights: Mechanisms of Alternative Lengthening of Telomeres (ALT) in cancer cells Telomere replication stress and its role in disease Development of telomere-specific therapeutic strategies Investigations into RNA-binding proteins in telomerase activity Recent Publications demonstrate expertise in telomere dynamics, DNA repair pathways, and cancer genomics across multiple journals like Nature Structural and Molecular Biology and Science . Key trends include targeting ALT mechanisms for cancer therapy, telomere stress markers, and genomic instability in sarcomas. Scientific Grants include funding from the US Department of Defence, Australian Department of Health, and NHMRC for projects like "Prevention of bone marrow failure in Fanconi anemia" and "Alternative Lengthening of Telomeres (ALT): Target Discovery to Treatment." Students advised include Deborah Nazareth: Recombinant AAV vector design for hepatocellular carcinoma Jake Schwenke: Synthetic lethality with FANCM inhibition in ALT-negative cancers

Erik BlackwoodView profile

Assistant Professor

• Cardiometabolic Disease
• Heart Failure
• Cardiac Fibrosis
• +6 more

Erik Blackwood is an Assistant Professor in the Department of Nutrition & Integrative Physiology at the University of Utah, specializing in cardiometabolic diseases and proteostasis mechanisms. His research focuses on heart failure (HFpEF and HFrEF), inter-organ communication, and therapeutic development for cardiac fibrosis. Education : BS from University of Notre Dame, PhD from San Diego State University Research Themes : Cardiac proteostasis, endoplasmic reticulum stress, cardiometabolic health, inter-organ signaling His lab investigates: SGK1-PRAS40 signaling in cardiometabolic heart failure IRE1-induced mRNA degradation in cardiac fibrosis Translational applications of proteostasis modulation Current studies leverage mouse models, primary cardiomyocytes, and small molecule activators to develop novel therapies for heart failure.

D. Matthew WachowiakView profile

Professor

• Olfaction
• Neural representations of odors
• Sensory processing
• +5 more

D. Matthew Wachowiak is a Professor in the Department of Neurobiology at the University of Utah School of Medicine, where he serves as Principal Investigator of the Wachowiak Lab. His research focuses on understanding how neural circuits transform sensory representations, with particular interest in how animals actively acquire sensory information to guide behavior. He uses the mouse olfactory system as a powerful model to analyze sensory representations and investigate how the dynamics of neural circuits process incoming information to guide behavior and shape perception. Dr. Wachowiak's educational background includes: PhD from University of Florida Postdoctoral Fellowship at Yale University School of Medicine Multiple Fellowships at Marine Biological Laboratory BS from Duke University His research program centers on four interconnected areas: (1) Olfaction as an Active Sense, investigating how sniffing shapes odor representations; (2) Cracking the Olfactory Code, analyzing how odor information is represented across the olfactory bulb; (3) Organization of Inhibition in the Olfactory Bulb, studying how synaptic inhibition shapes odor processing; and (4) Top-down Modulation of Olfactory Processing, examining how neuromodulatory pathways affect early olfactory processing. His lab employs optical reporters of neural activity targeted to genetically-defined neuron populations, two-photon imaging in awake behaving animals, and custom olfactometers for precise odor delivery. Dr. Wachowiak's publication record demonstrates consistent contributions to understanding the neural basis of olfaction, with recent work focusing on how sniffing parameters affect odor representations, mitral/tufted cell processing, and olfactory bulb inhibition. His lab has developed innovative tools including high-throughput olfactometers and functional atlases of odorant responses, contributing significantly to the field's methodological toolkit. His research has received substantial funding including: NSF Neuronex Award under the BRAIN Initiative as part of the 'Odor2Action' network NSF IDEASLab funding As a mentor, Dr. Wachowiak has guided numerous students and postdoctoral fellows who have established independent research programs at institutions including Yale University, Rutgers University, University of Florida, and University of Magdeburg. His lab continues to recruit graduate students through the University of Utah's Interdepartmental Program in Neuroscience and welcomes postdoctoral researchers interested in olfactory neuroscience. The Wachowiak Lab maintains state-of-the-art facilities for in vivo imaging, including widefield and high-resolution two-photon microscopy systems, custom olfactometers, and behavioral setups combining odor presentation with locomotion tracking. They actively collaborate with researchers across the US, UK, and Canada through the 'Odor2Action' project, which addresses how high-dimensional sensory variables are represented in brain circuits and mapped to actions.