Zhen Zhang

Zhen Zhang is a Postdoctoral Associate in Neuroscience at Yale School of Medicine. Their research focuses on developing radiolabeled compounds and molecular imaging agents for cancer diagnosis and therapy. Key areas include FAP-targeted imaging for fibrosis, GRPR-targeted probes for prostate cancer, and CXCR4 antagonists for hematologic malignancies. They have pioneered novel radiopharmaceutical designs using boronic acids, thiazolidine derivatives, and albumin-binding motifs to enhance tumor specificity and reduce off-target effects. Recent work emphasizes PSMA-targeted agents for prostate cancer imaging with improved kidney/salivary gland sparing profiles. Their preclinical studies span theranostic applications in multiple myeloma and melanoma models.