Zhen Lei

Zhen Lei is a Research Fellow in the Department of Neuroscience at the Yale School of Medicine, affiliated with the Guo lab. His research focuses on epigenetic mechanisms regulating transposon mobilization, RNA modifications, and phase separation in plant systems. Key areas include m6A RNA methylation, stress granules, and the interplay between ribosome stalling and chromatin organization.

He received the 2025 Kavli Postdoctoral Fellowship for his contributions to understanding transposon regulation. His work bridges molecular biology, cell biology, and plant genetics, with implications for epigenetic control in response to environmental stress.

Lei’s lab is located at R225, 100 College Street, New Haven, CT. His research employs advanced techniques in RNA biology, live-cell imaging, and biochemical assays to dissect mechanisms underlying transposon silencing and phase separation dynamics.