Yue Guo

Yue Guo is an Assistant Professor in the Department of Information Sciences at the University of Illinois. Her research focuses on natural language processing (NLP), biomedical informatics, and healthcare communication. She explores how large language models (LLMs) can improve lay language summarization of complex scientific content, particularly in healthcare contexts. Her work emphasizes personalized jargon detection, factuality evaluation of summaries, and accessibility of health information for diverse audiences.

Guo has also conducted extensive studies on radiation oncology outcomes, including xerostomia (dry mouth) recovery in head and neck cancer patients and the impact of radiation dose patterns on patient-reported symptoms. Her interdisciplinary research bridges computational methods with clinical needs, aiming to enhance patient understanding and care through advanced NLP techniques.

Her recent articles (2021–2025) highlight trends in LLM-driven biomedical communication, evaluation of health summaries, and data-driven approaches to cancer treatment optimization. Notable projects include APPLS (a summarization metric framework) and personalized jargon identification systems for interdisciplinary collaboration.

Guo teaches IS 504: Sociotechnical Information Systems, integrating technical and human factors in information systems design.