About
Yi David Xu is an Assistant Professor at Loma Linda University School of Medicine, Department of Medicine, focusing on biomedical research at the intersection of oncology, molecular biology, and immunotherapy. His work addresses critical challenges in cancer treatment through innovative molecular and translational approaches.
- Key research areas include acute myeloid leukemia (AML), KRAS-mutated pancreatic cancer, and mechanisms of drug resistance.
- He investigates subclonal evolution, gene fusions, chimeric RNA variants, and the tumor microenvironment.
Recent publications highlight nutrient-gene therapy to enhance CAR T cell efficacy, targeting the NFκB2-driven axis in pancreatic cancer, and characterizing prognostic biomarkers in AML. His studies integrate molecular biology with translational applications, emphasizing metabolic and genetic strategies to overcome therapeutic barriers.
Collaborations with researchers like David Baylink and H. Abdel-Azim underscore interdisciplinary efforts in regenerative medicine and cancer biology. No awards, grants, or advising details are explicitly mentioned in the provided text.
