Yeong-Renn Chen

Dr. Yeong-Renn Chen is a tenured Professor in the Department of Biomedical Sciences at Northeast Ohio Medical University (NEOMED), where he has worked since 2010. His research focuses on mitochondrial biology and redox regulation in cardiovascular diseases, particularly myocardial ischemia-reperfusion injury. He earned a B.S. in Agricultural Chemistry at National Taiwan University and a Ph.D. in Biochemistry and Molecular Biology from Oklahoma State University.

• Colleges of Medicine, Northeast Ohio Medical University
• Department of Biomedical Sciences
• Former positions at The Ohio State University (1997-2010)

Dr. Chen’s research explores mitochondrial dysfunction, oxidative post-translational modifications, and redox signaling in cardiovascular diseases. His work employs electron paramagnetic resonance (EPR) and mass spectrometry to study protein modifications in post-ischemic hearts.

Recent publications highlight his focus on mitochondrial complexes (I, II, III), diabetic vascular dysfunction, metabolic syndrome, and oxidative stress in cardiovascular pathologies. Key themes include mitochondrial electron transport chain, protein thiyl radicals, and antioxidant interventions.

He teaches medical physiology courses, including Microcirculation, Cellular Bioenergetics, and Renal Transport Physiology, integrating mitochondrial biology into clinical contexts.