
Yan Zhang
Assistant Professor · Polycystic Kidney Disease
Michigan Technological UniversityAbout
Yan Zhang is a Research Assistant Professor in the Department of Biological Sciences at Michigan Technological University. Their work focuses on autosomal dominant polycystic kidney disease (ADPKD), investigating the role of innate immunity in ADPKD's pathological microenvironment and the function of polycystin-1 encoded by the PKD1 gene. They are actively developing therapeutic strategies to target cyst formation and fibrosis in ADPKD.
Education:
- PhD in Pharmacology and Toxicology from the University of Missouri-Kansas City
- MS in Pharmacology from Peking Union Medical College
- BS in Pharmacy from Sichuan University
Research Trends: Recent publications highlight molecular mechanisms of cyst growth in ADPKD, including B-Raf signaling, mTOR-mediated proliferation, TGF-β1-induced fibrosis, and dietary phosphate restriction as potential therapeutic interventions. Subfields span from genetic disorder analysis to translational research in renal pathology.
Advising: No student names are listed in the available information.
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