Xin Wen

Xin Wen is a Research Fellow in the Department of Physics at the University of Michigan, located in Ann Arbor. His research focuses on autophagy mechanisms across yeast and mammalian systems, with particular emphasis on cellular stress responses, metabolic regulation, and disease implications. His work explores the interplay between transcriptional regulators, organelle dynamics, and environmental adaptation.

Key research areas include autophagy regulation in response to nutrient deprivation (e.g., nitrogen starvation), bacterial pathogen interactions (e.g., Salmonella), and the role of autophagy in cancer biology. He has contributed to standardized assay protocols for autophagy monitoring and investigates evolutionary conservation of stress response pathways.

Xin Wen's publications span molecular biology, cell biology, and medical science, with notable contributions to understanding ULK1 phosphorylation, Vac8 protein localization, and the Spt4-Spt5 transcriptional complex. His work bridges fundamental biological processes with translational applications in healthcare technology, such as digital health interventions for adolescent weight management.

Contact details: Office at Randall Lab & Homer A. Neal Lab, 450 Church Street, Ann Arbor, MI 48109-1040. Email: xnwn@umich.edu.