Xavier Rios

Xavier Rios is an Assistant Professor in the Department of Pediatrics (Hematology and Oncology) at Baylor College of Medicine in Houston, Texas. His research focuses on advancing immunotherapies, particularly CAR-T and CAR-NKT cell therapies, using CRISPR/Cas9 and pooled screening techniques to enhance efficacy against neuroblastoma and improve effector cell persistence. He also investigates nutritional iron deficiency anemia management in pediatric emergency care. Rios has contributed to gene editing tools, recombinase technologies, and synthetic biology applications.

His academic work spans over two decades, with significant publications in immunology, oncology, and molecular biology. Key research areas include metabolic reprogramming of immune cells, PRDM1 regulation in NK T-cells, and refining CAR designs through barcoded protein domain screening. He has explored CRISPR mutagenesis for next-generation therapies and pioneered improved bacterial recombineering methods.

Rios has contributed to clinical standards for pediatric anemia management and studied genetic syndromes like Xq13.1 duplication-linked T-cell lymphopenia. His lab integrates cutting-edge genomic and biotechnological approaches to address unresolved challenges in pediatric oncology and hematology.