Xavier Llor

Xavier Llor, MD, PhD is a Professor of Medicine at Yale School of Medicine and directs the GI & Pancreatic Cancer Prevention Program. He leads the Lynch Syndrome and Polyposis Clinic and Hereditary Gastric Cancer clinic, specializing in gastrointestinal cancer genetics and colorectal cancer prevention. His research focuses on hereditary cancer syndromes (e.g., Lynch syndrome), disparities in cancer outcomes, and improving genetic screening methodologies. He holds appointments in the Department of Medicine (Digestive Diseases) and serves on key committees including the NCCN Guidelines panels for Colorectal Cancer Screening and Genetic/Familial High-Risk Assessment.

Education & Training:

• MD: University of Barcelona (1986)
• PhD in Molecular Biology: University of Barcelona (1999)
• Residency: Internal Medicine, University of Chicago-Lutheran General Hospital (1994)
• Fellowship: Gastroenterology, University of Illinois at Chicago (1997)

Research Focus: Dr. Llor's work bridges clinical practice and translational research, addressing:

• Molecular mechanisms of hereditary colorectal cancers
• Health disparities in cancer outcomes among African Americans and Latinos
• Development of genetic testing criteria (e.g., NCCN/Yale CDH1 criteria)
• Implementation science for improving Lynch syndrome identification

Awards & Recognition:

• 2016: Mentor, Future Leaders Program (AGA)
• 2012: Distinguished Mentor Award (Yale School of Medicine)

Clinical Contributions: Leads initiatives to expand access to genetic counseling and screening for underserved populations. His team developed an EMR-based automated system improving Lynch syndrome detection in disadvantaged patients.

Leadership Roles:

• Chair, Practice Implementation & Professional Education (PEPI) Health Systems (NCCRT)
• Member, NCCN Colorectal Cancer Screening Panel