Victoire de Lastours

Dr. Victoire de Lastours is a Permanent researcher with the rank of PU-PH (Professeur des Universités - Praticien Hospitalier) at Université Paris Cité, where she contributes to the IAME institute and the EVRest research team. As co-leader of Axis 3 focused on 'Antibiotic repurposing and phage therapy,' she plays a pivotal role in addressing one of modern medicine's greatest challenges: antimicrobial resistance.

Her research spans multiple critical domains in infectious diseases:

• Antibiotic resistance mechanisms and evolution in Escherichia coli
• Bacterial virulence factors and pathogenesis
• Gut microbiota dynamics during antibiotic treatment
• Clinical evaluation of antibiotic treatment durations
• Development of alternative therapeutic approaches including phage therapy

Dr. de Lastours employs a multidisciplinary methodology integrating laboratory research, genomic analysis, clinical trials, and epidemiological investigations. Her publications in high-impact journals demonstrate consistent contributions to understanding resistance transmission, evaluating treatment strategies, and exploring novel therapeutic approaches that bridge basic science with clinical applications.

Her recent work shows particular emphasis on:

• Mechanisms and spread of ESBL-producing E. coli
• Evolution of resistance during antibiotic treatment
• Genomic determinants of bacterial virulence
• Clinical trials optimizing antibiotic therapy duration
• Innovative approaches to combat multidrug-resistant infections

Through her leadership in the EVRest team and participation in international research groups like COLIBAFI and SEPTICOLI, Dr. de Lastours contributes significantly to the global effort against antimicrobial resistance, with implications for clinical practice, public health policy, and future therapeutic development.