V.B. S. Prasath

Dr. V.B. S. Prasath is a Professor in the Department of Biomedical Informatics at the University of Cincinnati and leads the Prasath Lab at Cincinnati Children's Hospital Medical Center (CCHMC). His research focuses on AI/ML-driven biomedical informatics, integrating genomics, imaging, and clinical data to address pediatric healthcare challenges. The lab collaborates with multiple institutions, including the Center for Pediatric Genomics (CPG) and the National Institutes of Health (NIH).

Key research areas include:

• Medical imaging analysis (histopathology, MRI, ultrasound)
• Single-cell genomics (ATAC-seq, scRNA-seq, spatial transcriptomics)
• Multimodal data integration (scTriangulate framework)
• Antimicrobial resistance prediction (MGS2AMR)

Recent work includes developing tools like maxATAC for transcription factor binding prediction and DeepImmuno for immunogenic peptide analysis. The lab has secured grants from NIH, Cystic Fibrosis Foundation, and Crohn's & Colitis Foundation.