Uffe Hasbro Mortensen

Professor Uffe Hasbro Mortensen is affiliated with the Department of Biotechnology and Biomedicine at the Technical University of Denmark (DTU), leading the Section for Synthetic Biology. His research focuses on DNA repair mechanisms and genetic instability to develop stable microbial strains for bioproduction and cancer mechanism understanding.

Key research areas include:

• CRISPR-based genome engineering in filamentous fungi
• Heterologous small molecule production in yeast
• Comparative genomics of Aspergillus species
• Optimization of protein secretion pathways
• Synthetic biology for industrial applications

He supervises multiple PhD projects, including topics on:

• Secondary metabolite gene clusters
• Fungal enzyme discovery for plastic degradation
• High-throughput genetic engineering tools
• Natural product biosynthesis

Current projects emphasize Aspergillus engineering for sustainable bioproduction and fungal systems biology.