Tom Hodgkinson

Dr. Tom Hodgkinson is a Research Lecturer in Anatomy and Regenerative Medicine at RCSI, focusing on regenerative strategies for osteochondral repair and osteoarthritis treatment. His research develops biomaterial-based nucleic acid delivery systems to control inflammation and promote tissue regeneration. Current projects explore mechanical regulation of cell behavior and epigenetic reprogramming for cartilage rejuvenation.

Research interests include biomaterial-mediated gene delivery, cellular mechanobiology, and metabolic regulation in age-related tissue degeneration. His work spans fundamental biomaterial design to translational applications for cartilage and bone repair, employing 3D bioprinting, nanovibration platforms, and siRNA-activated scaffolds.

Publication analysis shows progressive development of biomaterial systems for joint repair, from early growth factor delivery work to advanced gene-activated scaffolds. Recent innovations include albumin nanoparticles for intra-articular drug delivery and 3D printable collagen-hyaluronic acid hydrogels.

Major grants include Horizon Europe and Science Foundation Ireland funding for inflammation-responsive gene circuits and cartilage regeneration strategies. Professional memberships include Orthopaedic Research Society and Controlled Release Society.

Laboratory research focuses on developing adaptable biomaterial platforms for diverse tissue environments, with particular emphasis on overcoming inflammation-mediated regeneration barriers in osteoarthritis.