About
Dr. Tim Triche, Jr. is an Associate Professor in the Department of Epigenetics at Van Andel Institute (VAI). He leads the Triche Laboratory, focusing on epigenetic mechanisms in pediatric acute myeloid leukemia (AML) and translational bioinformatics. His work integrates genomic profiling, clinical trial design, and statistical approaches to improve cancer therapy. Key affiliations include VAI's Bioinformatics and Biostatistics Core and collaborations with the Cancer Genome Atlas Research Network (TCGA).
Education: A.B. in Chemistry (Cornell University), M.S. in Biostatistics and Ph.D. in Statistical Genetics (USC). Postdoctoral training at USC's Norris Comprehensive Cancer Center. Active in organizations like the American Society of Hematology and AACR.
Research interests span leukemia biology, computational methods for cancer genomics, and epigenetic biomarkers. His team develops tools like BISCUIT and CelFiE-ISH for genetic/epigenetic analysis. Notable grants include Chan Zuckerberg Initiative and NCI SPORE funding. Over 120 peer-reviewed publications in high-impact journals like Nature and Cell.
Advises graduate students in VAI's Graduate School, mentoring on projects like pediatric AML genetics and clinical trial design. Lab alumni include postdocs and interns contributing to leukemia research and bioinformatics.
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