Thomas Ve

Dr. Thomas Ve is a structural biologist and research leader at the Institute for Biomedicine and Glycomics at Griffith University, with affiliations since 2015. He holds prestigious fellowships including NHMRC Investigator Grant and ARC Future Fellowship, and leads research on NAD+ metabolite signaling in axon degeneration and immune responses.

• PhD, University of Queensland (2011)
• MSc, University of Bergen (2006)

His research focuses on structural and biochemical analysis of protein-ligand interactions, particularly TIR domains in:

• TLR signaling pathways
• Neurodegenerative disease mechanisms
• Bacterial and plant immunity
• NAD+ signaling in cell death
• Structure-based drug discovery
• Cryo-EM/X-ray crystallography

Recent publications highlight structural characterization of:

• TIR-domain signalosomes
• Antiphage defense systems
• Enzymatic regulation in pathogens
• Therapeutic targeting of SARM1

Scientific awards include:

• Shimadzu Medal (2024)
• NHMRC Investigator Grant
• ARC Future Fellowship

Dr. Ve has supervised 12+ doctoral students in:

• Structural neuroprotection
• TIR domain inhibition
• Glycosylation in cancer
• Nucleotide analog development

He currently leads NHMRC and ARC-funded projects totaling over $3.6 million focused on:

• Neurodegenerative disorder therapies
• Plant immune signaling
• Bacterial NADase targets