Thomas Powles

Professor Thomas Powles is a renowned academic in the field of Genitourinary Oncology. He serves as the Director of the Barts Cancer Centre at St Bartholomew's Hospital, where he leads the Solid Tumour Research Group. His research focuses on advancing clinical studies for genital and urinary cancers, spanning phases I to III, with an emphasis on novel targeted and immune therapies.

His recent publications highlight groundbreaking work in immune checkpoint inhibitors like Pembrolizumab and Avelumab, particularly for renal-cell and urothelial carcinomas. Key themes include:

• Translational phase II clinical trials
• Adjuvant therapy development
• Antibody-drug conjugate research
• Metastatic cancer treatment strategies

Professor Powles contributes to major funding initiatives as Co-Lead of the Barts Experimental Cancer Medicine Centre and NIHR Biomedical Research Centre. Additional roles include:

• Editor-in-Chief of the Annals of Oncology Journal
• Co-Lead of European Guidelines for GU Cancer
• Co-Host of the Uromigos Podcast