Thomas Gillette

Thomas Gillette, Ph.D., is an Associate Professor in the Department of Internal Medicine at UT Southwestern Medical Center and a member of the Division of Cardiology. His academic career spans roles as Instructor of Physiology (2004), Assistant Professor of Physiology (2005), Assistant Professor of Internal Medicine (2009), and Associate Professor since 2016.

• Bachelor's in Biology, Manhattanville College
• Postdoctoral training in Biochemistry, NYU Medical Center Sackler Institute
• Postdoctoral fellowships under Drs. Errol Friedberg and Stephen Johnston at UT Southwestern

Dr. Gillette's research focuses on heart failure mechanisms, including regulation of cardiac function, ischemia/reperfusion injury, cardiac hypertrophy, and autophagy. His work explores proteasome biology, epigenetic regulation, and calcium signaling pathways in cardiomyocytes.

Key trends in his publications include proteasome function in cardiac disease (2001-2016), autophagy in heart failure (2009-2016), and epigenetic regulation in cardiovascular pathologies (2015-2016). He has co-authored studies on HDAC inhibitors, FoxO signaling, and ryanodine receptor degradation.

Dr. Gillette collaborates with Dr. Joseph Hill and is affiliated with the Hill Lab at UT Southwestern. He is a member of the American Heart Association's Council on Basic Cardiovascular Sciences.