About
Themis R. Kyriakides is a Professor of Pathology at Yale University, affiliated with the Yale School of Medicine. He holds a PhD from Washington State University (1993) and completed a postdoctoral fellowship at the University of Washington. His research focuses on cellular and molecular mechanisms governing inflammation, angiogenesis, and tissue regeneration in response to biomaterials. Key areas include thrombospondin-2 (TSP-2) regulation, extracellular matrix interactions, and development of bioengineered materials for medical applications.
Education:
- PhD in Biomedical Sciences, Washington State University, 1993
- Postdoctoral Fellowship in Pathology, University of Washington, 1998
Research Interests:
Dr. Kyriakides investigates molecular events at the interface between biomaterials and tissues, emphasizing vascular graft engineering, diabetic wound healing, and extracellular matrix remodeling. His lab develops tunable hydrogels and biomaterials to modulate immune responses and enhance tissue repair. Recent work explores TSP-2’s role in fibroblast function and neointimal hyperplasia in vascular implants.
Awards:
- Elected Fellow of the American Institute for Medical and Biological Engineering (AIMBE), 2020
Advising & Grants:
He mentors students in Biomedical Engineering and Pathology. Notable advisees include Hao Xing (PhD student) and Britta Kunkemoeller (postdoctoral researcher). His lab receives funding from the NIH and industry partnerships for projects on hydrogel design and biomaterials.
Labs/Teams:
Director of the Kyriakides Lab, focusing on translational research in vascular biology and biomaterials. Collaborations include the Yale Fibrosis Program and Diabetes Research Center.
