Takashi Angata

Takashi Angata is a Principal Investigator at the Institute of Biochemistry, Academia Sinica, with a research focus on sialic acid-Siglec interactions and their roles in mammalian physiology and human diseases. His work explores how glycan-binding proteins like Siglecs influence immune regulation and pathogenesis.

• Current research targets Siglec DNA polymorphisms and their connection to clinical disease manifestations
• Developing diagnostic and therapeutic strategies based on sialic acid biology

His recent publications highlight glycan engineering, immune-modulatory mechanisms, and Siglec ligand discovery across disciplines of immunology, biochemistry, and molecular evolution. The laboratory employs glycan analysis, structural biology, and cell interaction studies to address disease-relevant questions.

Dr. Angata's collaborations span glycobiology and oncology, with applications in infectious disease and cancer immunotherapy. His work integrates biomedical research with translational outcomes.