Sven Rottenberg

Prof. Dr. Sven Rottenberg is a Group Leader at the Institute of Animal Pathology within the University of Bern, and a member of the Neglected Diseases Cluster at the Multidisciplinary Center for Infectious Diseases (MCID). His research spans oncology and infectious diseases, focusing on DNA damage response mechanisms, PARP inhibitor resistance, and comparative oncology using canine/feline models.

• Specializes in spatial transcriptomics and CRISPR/Cas9 functional genomics
• Develops AI-driven tools for digital pathology and drug safety assessment
• Investigates tumor microenvironment dynamics and metabolic vulnerabilities

Research Trends: His recent work emphasizes

• Spatial omics technologies for tumor heterogeneity mapping
• Host-pathogen interactions in malaria and hemoparasites
• Artificial intelligence applications in veterinary and human oncology
• Genetic dropout screens for chemotherapy optimization
• Replication fork stability in BRCA-deficient cancers
• Canine tumor organoid biobanking