Stuart Wilson

Professor Stuart Wilson holds the Roper Chair in Genetics at the School of Biosciences, University of Sheffield (2019-present). He previously served as Professor (2008-2019), Reader (2008), and Senior Lecturer (2003-2007) at the same institution.

• Education
  • PhD in Biochemistry (1987-1991), University College London
  • BSc in Cell and Molecular Biology (1984-1987), King's College London
• Research Themes
  • Gene expression regulation via RNA binding proteins
  • Nuclear mRNA processing and cytoplasmic transport
  • Disease mechanisms in motor neuron disease and hnRNPU syndrome
  • m6A RNA modification and TREX complex dynamics
  • Herpesvirus mRNA export strategies
  • Biopharmaceutical expression systems for CHO cells
• Publication Trends
  • 2023-2025 preprints focus on 3' UTR splicing in oncogene regulation, m6A modification in herpesvirus replication, and RNA binding protein evolution
  • 2019-2018 work on co-transcriptional RNA export and m6A methylase complex interactions
  • 2014-2015 studies on C9orf72 repeat expansions in neurodegeneration
• Scientific Collaborations
  • Co-founder of Sheffield Institute for Nucleic Acids (SInFoNiA)
  • Collaborations with AstraZeneca for biopharma development
  • Multi-institutional work on m6A RNA modification
• Research Group
  • Graduate students developing CHO cell expression systems and RNA binding protein-DNA damage connections
  • Postdocs investigating synthetic mRNA UTRs and hnRNPU syndrome gene therapy
  • Laboratory manager Vicky Porteous-Medley