Struan F.A. Grant

Struan F.A. Grant is a distinguished Professor of Pediatrics (Human Genetics) at the University of Pennsylvania and a Professor of Genetics at the Perelman School of Medicine. He holds the Daniel B. Burke Endowed Chair for Diabetes Research and serves as Director of the Center for Spatial and Functional Genomics at Children's Hospital of Philadelphia (CHOP). His work bridges human genetics with pediatric disease genomics, focusing on obesity, diabetes, and bone disorders.

• Current affiliations: UPenn, CHOP
• Graduate group affiliations: Cell and Molecular Biology, Genomics and Computational Biology

Research Focus: With over 25 years of experience, Grant's career highlights include discovering the COL1A1 polymorphic Sp1 site linked to osteoporosis and the TCF7L2 gene's role in type 2 diabetes. His current work leverages high-throughput genomics and bioinformatics to unravel pediatric disease mechanisms, particularly in obesity and metabolic disorders where genetic factors are more discernible due to limited environmental exposure.

Scientific Awards:

• Wellcome Postdoctoral Fellowship
• Daniel B. Burke Endowed Chair for Diabetes Research

Advising & Funding: Mentored numerous trainees including Max F. Dudek and Elizabeth A. Burton. Active funding includes grants from NIH (R01 HD056465, R01 HD100406, R01 AG072705, UM1 DK126194) and co-investigator roles in R01 NS135075, R01 AI154773, and P01 HL160471.