Steven R. Tannenbaum

Steven R. Tannenbaum

Steven R. Tannenbaum holds the Underwood-Prescott Professorship in Biological Engineering, Chemistry, and Toxicology at MIT. His primary affiliation is with the Department of Biological Engineering. The Tannenbaum Lab focuses on nitrosation chemistry, oxidative stress mechanisms, and advanced drug metabolism analysis using cutting-edge technologies.

Research Focus

Key areas include:

• Endogenous nitrogen oxide synthesis and biological impacts
• DNA damage pathways from nitrosative stress
• Organized tissue-based in vitro toxicity sensors
• High-sensitivity mass spectrometry for ADME studies

Technical Innovations

Developed micro-tissue chips combined with mass spectrometry/optical sensors for rapid drug/toxin screening. Pioneered 'nanotracing' using accelerator mass spectrometry for molecular tracking at sub-femtomole levels.

Lab Members

Current lab includes researchers like Haitham Amal, Guanyu Gong, Xin Wang, and Pete Wishnok (seen in 2017 group photo). Administrative support provided by Darlene Ray.

Alumni information available through lab archives, though specific former student names are not listed in current materials.