Stephen Clarke

Professor Stephen Clarke is a distinguished academic and clinician at the University of Sydney, affiliated with the Medicine, Northern Clinical School and the Kolling Institute of Medical Research. He holds the title of Professor of Medicine and specializes in oncology, with a focus on cancer pharmacology, colorectal and lung cancers. His research integrates clinical trials, translational research, and the exploration of biomarkers and therapeutic strategies in oncology.

Professor Clarke’s work spans diverse areas including the use of imaging techniques (e.g., PET/CT), precision medicine, and the impact of systemic inflammation on cancer outcomes. He has contributed to advancements in targeted therapies, immunotherapy, and supportive care, including studies on cannabis-based pain management.

His research interests also extend to the gut microbiome’s role in cancer treatment response and toxicities, as well as the development of probiotic interventions to mitigate treatment side effects. He has led or collaborated on numerous clinical trials, including studies of stereotactic body radiotherapy for pancreatic cancer and immunotherapy combinations in lung cancer.

Professor Clarke has been recognized with the Order of Australia Medal (OAM) for his contributions to medicine. His publications emphasize translational research, with a focus on improving patient outcomes through evidence-based approaches in oncology.