About
Stephen Bunnell is an Associate Professor in the Department of Immunology at Tufts University School of Medicine. His research focuses on T cell signaling complexes and their dynamic regulation during activation, utilizing advanced imaging and biochemical techniques. He holds a Ph.D. from Harvard University (1998) and a B.A. from Cornell University (1990).
- Education:
- Doctor of Philosophy, Harvard University, USA, 1998
- Bachelor of Arts, Cornell University, USA, 1990
His research explores the assembly, localization, and functional implications of signaling microclusters in T cells, with a focus on proteins critical for complex stability and signal generation. Recent projects include studies on polyubiquitin scaffolds, vesicle transport, and innate immune receptors in dendritic cells and neutrophils. His work bridges imaging, biochemistry, and functional assays to elucidate mechanisms underlying T cell activation and immune dysfunction.
Key grants include NIH-funded projects on innate immunity, STING signaling, and T cell receptor dynamics. Collaborations within Tufts and beyond aim to translate mechanistic insights into therapeutic strategies for immunodeficiency, autoimmunity, and immunotherapy. Teaching responsibilities include immunology courses and journal clubs at the graduate level.
Professional activities include membership in the American Association of Immunology and the American Association for the Advancement of Science.
