About
Staffan Rosenborg is an Adjunct Lecturer and Docent at Karolinska Institutet's Department of Laboratory Medicine, specializing in the Division of Clinical Pharmacology. His work focuses on drug interactions, pharmacokinetics, and therapeutic drug monitoring, with particular expertise in renal pharmacology and clinical laboratory medicine.
His educational background includes:
- Docent (2022) from Karolinska Institutet
- PhD in Laboratory Medicine (2010) from Karolinska Institutet
- Medical Degree (1996) from Karolinska Institutet
Dr. Rosenborg's research spans multiple areas of clinical pharmacology with a strong emphasis on drug metabolism, therapeutic drug monitoring, and pharmacokinetics. His work frequently examines drug interactions, particularly those involving cytochrome P450 enzymes, and investigates appropriate dosing strategies for patients with renal impairment. He has conducted significant research on antibiotic effects on microbiota, methylphenidate pharmacokinetics in various populations, and ketone body metabolism in older adults. His expertise bridges clinical practice with laboratory medicine, focusing on translating pharmacological research into practical clinical applications.
Analysis of his recent publications reveals a consistent focus on pharmacokinetic studies, drug safety, and therapeutic drug monitoring. His work often involves innovative sampling techniques including exhaled breath and oral fluid analysis as alternatives to traditional blood sampling. A significant portion of his research addresses challenges in renal pharmacology, including drug dosing adjustments for patients with kidney impairment. His studies frequently employ crossover trial designs and utilize advanced analytical methods such as LC-MS/MS for precise drug quantification.
Dr. Rosenborg has been involved in the development and evaluation of clinical decision support systems like Janusmed Renal Function, which aids in appropriate drug dosing for patients with renal impairment. His work demonstrates a strong commitment to improving medication safety and optimizing pharmacotherapy through evidence-based approaches.
