Sriram Neelamegham

Sriram Neelamegham is the UB Distinguished Professor of Chemical & Biological Engineering, Biomedical Engineering, and Medicine at the University at Buffalo, SUNY. His research focuses on applying engineering principles to study molecular mechanisms of blood cell interactions in diseases such as inflammation, thrombosis, and cancer. He leads the Bioengineering Laboratory within the School of Engineering and Applied Sciences.

Education:

• PhD in Chemical/Biomedical Engineering, Rice University, 1996
• B.Tech in Chemical Engineering, Indian Institute of Technology Delhi, 1991

Research Interests:

• Systems Glycobiology: Investigating glycan biosynthesis and its role in disease
• Leukocyte and Platelet Adhesion Dynamics under Fluid Flow
• Von Willebrand Factor (VWF) Structure-Function Relationships
• Engineering Glycoengineered Therapeutics and Diagnostic Tools

Key Contributions:

• Developed computational models and experimental tools for glycosylation pathway analysis
• Discovered mechanisms of VWF conformational changes under shear stress
• Pioneered glycoengineering strategies for stem cell targeting

Awards & Recognition:

• NIH Independent Scientist Award (2015)
• SUNY Chancellor's Award for Excellence (2015)
• AIMBE Fellow (2012) and BMES Fellow (2019)
• 2018 Schoellkopf Medal (ACS)

Lab Activities:

• Recruitment of postdocs, full-time, and part-time research technicians
• Development of glycan-engineered technologies for drug delivery and diagnostics
• Collaborations with biomedical industries and academic institutions