About
Sophie Deng is a Professor and Vice Chair of Ophthalmology at the University of California, Los Angeles (UCLA) School of Medicine, where she holds the Walton Li Chair in Cornea and Uveitis and previously held the Joan and Jerome Snyder Chair in Cornea Diseases (2019-2023). Her research focuses on corneal regeneration, limbal stem cell biology, and Wnt signaling pathways in ocular diseases.
- NIH R01EY028557: Co-PI for small-molecule Wnt mimetics in corneal regeneration (2018-2022)
- NIH R01EY021797: PI for stem cell therapies in limbal deficiency (2012-2024)
Her work has significantly advanced diagnostics (e.g., AS-OCT for epithelial thickness, subbasal nerve density) and therapeutic strategies (e.g., extracellular vesicles, 3D bioprinting). She collaborates extensively with researchers like Clemence Bonnet and Jin Zhang, contributing to 65+ peer-reviewed publications.
Scientific Awards:
- Walton Li Chair in Cornea and Uveitis
- Joan and Jerome Snyder Chair in Cornea Diseases (2019-2023)
Her 15 most recent articles (2025-2022) explore topics like exosome drug delivery, ANGPTL7 regulation, and machine learning in corneal imaging, emphasizing limbal stem cell deficiency, Wnt signaling, and biomedical engineering solutions.
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