Sine Reker Hadrup

Professor Sine Reker Hadrup is a leading academic at the Technical University of Denmark, where she serves as Head of Section in the Department of Health Technology, Experimental & Translational Immunology. Her research focuses on T-cell immunology, cancer immunotherapy, and neoantigen discovery, with a particular emphasis on leveraging immunogenicity prediction and peptide-MHC multimer technology for advanced cancer treatments.

• Department: Experimental & Translational Immunology
• School: School of Health Technology
• Academic Rank: Professor

Her work bridges computational biology with clinical immunology, exploring cross-reactive CD8+ T-cell responses to tumor and microbiota-derived antigens, as well as allogeneic stem cell transplantation monitoring. Recent publications highlight her contributions to T-cell receptor modeling, iPSC-T cell differentiation, and GEAR-T cell therapy development.

The latest studies by Prof. Hadrup's team demonstrate innovations in neoantigen vaccine design and computational prediction of immune regulators using single-cell transcriptomics. Her group's modular protein language models and minibinder engineering are pushing the frontiers of precision immunotherapy for cancer patients.