About
Dr. Simon G. Royce is a Senior Lecturer and Senior Research Fellow in Pharmacology at the Victorian Heart Institute (VHI), Monash University. He holds a Ph.D. in Pathology from the University of Melbourne and has established a prominent research program focused on chronic respiratory diseases, particularly asthma, COPD, and pulmonary fibrosis.
His research explores the molecular mechanisms of airway remodeling and fibrosis, with a strong emphasis on epigenetic regulation, inflammation, and the therapeutic potential of compounds such as sulforaphane, relaxin, and serelaxin. He also investigates nanoparticle-based drug delivery systems and stem cell therapies for lung diseases.
Dr. Royce’s recent publications demonstrate a consistent focus on anti-fibrotic and anti-inflammatory strategies using both murine and large animal models. His work spans pharmacological interventions, epigenetic modulation, and translational models of lung injury, with recurring themes in precision-cut lung slices, transgenic models, and novel therapeutic delivery systems.
He is actively involved in securing research grants and leads projects funded by the NHMRC, Victoria Medical Research Accelerator Fund, and iCARE NSW. His collaborative network includes Monash University, Penn State University, and industry partners such as Cynata Therapeutics and AusBio.
Dr. Royce supervises multiple doctoral students and has contributed to several patents, including methods for using induced pluripotent stem cell-derived mesenchymal stem cells to treat asthma. His work supports UN Sustainable Development Goal 3 (Good Health and Well-being) through innovations in chronic disease treatment.
Research fields
