Simbarashe Mazambani

Simbarashe Mazambani is an Assistant Professor of Instruction in the Department of Biological Sciences at the University of Texas at Dallas (UTD), affiliated with the School of Natural Sciences and Mathematics. His academic preparation includes a Ph.D. in Molecular and Cell Biology from UTD (2023), an M.S. in Biological Sciences from Texas A&M University-Commerce (2017), and a B.S. in Biological Sciences from the same institution (2014).

Dr. Mazambani's research focuses on cancer metabolism, biochemistry, and functional genomics, with a particular emphasis on metabolic vulnerabilities in squamous cell carcinomas and the role of glucose-insulin signaling pathways in tumor growth. His work integrates oxidative stress mechanisms, epigenetic regulation, and xenobiotic detoxification pathways to elucidate cancer progression and therapeutic strategies.

Notable publications include groundbreaking studies on targeting the glucose-insulin axis in head and neck squamous cell carcinoma, the role of Hedgehog signaling in lung adenocarcinoma suppression, and epigenetic control of breast cancer via xenobiotic pathways in agouti mouse models. His research spans disciplines such as oncology, cell signaling, and metabolic reprogramming, with implications for precision medicine and cancer therapy.

Dr. Mazambani currently does not accept undergraduate or graduate students, focusing instead on instructional and research activities. His work is supported by experimental models and collaborative studies, though specific grants or lab affiliations are not detailed in the provided materials.