About
Dr. Silvia Gramolelli is an Academy Research Fellow at Åbo Akademi University's Faculty of Science and Engineering, affiliated with the Biochemistry and Cell Biology group under the InFLAMES flagship program. She has received the Academy Research Fellow award from Finland's Academy.
- Research Focus: Oncogenic viruses (Kaposi's Sarcoma-Associated Herpesvirus, Epstein-Barr virus) and their interactions with cellular transcription factors/molecular pathways.
- Key Mechanisms: Chromatin remodeling, promoter regulation, tumor microenvironment crosstalk, and viral genome amplification.
Publication Trends: Recent works (2020-2025) explore gamma-herpesvirus gene expression, melanoma-endothelial cell interactions via NOTCH/WNT axes, and viral replication mechanisms independent of cell cycle regulators. She investigates how viruses co-opt host transcription factors like SOX18/PROX1 for oncogenesis.
Scientific Recognition: Her research appears in high-impact journals like PLoS Pathogens and Cancer Research, with one article referenced in a patent and multiple receiving news/blog coverage. She leads the 2023-2027 Academy of Finland project on EBV-associated gastric cancer mechanisms.
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