Signe Meng

Signe Meng serves as a Guest Researcher in the Department of Biology at the University of Copenhagen, specializing in Cell Biology and Physiology. Her work focuses on molecular mechanisms driving cancer progression, particularly within breast cancer metastasis pathways.

Her research expertise spans Cancer Biology and Cell Biology, with concentrated investigations into invadopodia dynamics, extracellular matrix degradation, and protein interactions involving MCT4, CD147, and MMP14. Current studies examine how these molecular complexes facilitate tumor cell invasion through tissue barriers.

Recent publication trends demonstrate consistent focus on breast cancer invasion mechanisms, with her 2024 Journal of Cell Science article establishing critical links between MCT4/CD147 colocalization with MMP14 in invadopodia and their functional role in matrix degradation. This work contributes to identifying potential therapeutic targets for metastatic breast cancer.