Shabaz Mohammed

Shabaz Mohammed is an Associate Professor of Proteomics at the University of Oxford, holding joint appointments in the Departments of Chemistry and Biochemistry. Since 2020, he has served as Head of the Mechanistic Proteomics research programme at the Rosalind Franklin Institute. His research focuses on advancing proteomics technologies to study protein post-translational modifications and their roles in cellular processes, with applications in viral infections and disease mechanisms.

Education:

• BSc in Chemistry, UMIST (now The University of Manchester), 1999
• PhD in Biological Mass Spectrometry, University of Manchester, 2003
• Postdoctoral Research, University of Southern Denmark (with Ole Jensen), 2005-2008
• Postdoctoral Research, Utrecht University (with Albert Heck), 2008

Professor Mohammed's research centers on developing novel mass spectrometry approaches for large-scale characterization of protein post-translational modifications (PTMs). His group innovates in chromatographic techniques for single-cell proteomics, creates materials for PTM enrichment (glycosylation/phosphorylation), and applies these tools to study viral infections (SARS-CoV-2), cell cycle regulation, and signaling pathways. His work bridges chemistry, biochemistry, and cell biology to understand dynamic protein functions in health and disease.

His recent publications (2023-2025) demonstrate strong emphasis on viral proteomics, particularly virus-host RNA-binding protein interactions, and innovations in mass spectrometry fragmentation techniques and chromatography. Key themes include viral remodeling of host cells, new labeling strategies for PTMs, and advancements in single-cell proteomics, with significant implications for understanding viral pathogenesis.

Scientific Awards:

No specific awards or fellowships were detailed in the source material.

Advising and Grants:

Information regarding graduate students supervised or specific research grants was not provided in the available text. As an active research group leader, Professor Mohammed likely mentors PhD students and secures competitive funding for proteomics research.

Laboratories and Collaborations:

Professor Mohammed leads a research group at Oxford focused on proteomics technology development. He collaborates extensively with the Ben Davis group on PTM detection materials and across the university on biochemical applications. At the Rosalind Franklin Institute, he heads the Mechanistic Proteomics programme to unravel protein functions through advanced proteomic methods.