Seth J. Orlow

Seth J. Orlow, MD, PhD is Samuel Weinberg Professor of Pediatric Dermatology and Professor in Cell Biology and Pediatrics at NYU Grossman School of Medicine. He serves as Chair of the Ronald O. Perelman Department of Dermatology and Director of the Program in Cutaneous Biology.

• MD/PhD in Molecular Pharmacology, Albert Einstein College of Medicine (1986)
• Residency & Fellowship: Yale-New Haven Medical Center (1989–1990)

His research spans three major areas: 1) Developing novel cancer therapeutics including melanoma treatments and chemoresistance pathways, 2) Investigating melanin synthesis mechanisms and oculocutaneous albinism, and 3) Studying vitiligo pathogenesis through endoplasmic reticulum stress models. Clinical focus includes pediatric eczema, psoriasis, and birthmark management.

Key research trends:

• Drug repositioning for melanoma and multiple myeloma
• Tyrosinase processing in pigmentation disorders
• AI applications in dermatology

Scientific Awards:

• Lifetime Achievement Award, American Skin Association (2003)

Currently treating patients at NYU Langone Dermatologic Associates (222 East 41st Street, New York, NY 10017) with expertise in acne, birthmarks, vitiligo, and genetic skin diseases.